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The map label for this gene is ppa [H]

Identifier: 169627622

GI number: 169627622

Start: 519150

End: 519638

Strand: Reverse

Name: ppa [H]

Synonym: MAB_0518c

Alternate gene names: 169627622

Gene position: 519638-519150 (Counterclockwise)

Preceding gene: 169627626

Following gene: 169627620

Centisome position: 10.25

GC content: 62.99

Gene sequence:

>489_bases
GTGGAGTTCGACGTCACCATCGAGATCCCCAAGGGTCAGCGCAACAAGTATGAGGTCGATCACGAGACCGGACGAGTGCG
TCTGGACCGCTTCCTCTACACCCCTATGGCGTACCCCACCGATTACGGCTTCATCGAAAACACGCTGGGCGAGGACGGCG
ATCCGCTGGACGCACTGGTGCTGCTGCCCGAGTCCGTCTTCCCGGGTGTGATCGTCGAGGCGCGGCCCGTCGGCATGTTC
AAGATGGTCGACGACGGCGGCGGCGACGACAAGGTGTTGTGCGTGCCCGCGGGCGACCCACGCTGGGACCACATCCAGGA
CATCGGCGATGTATCCAGCTTCGAGCTGGATTCGATCAAGCACTTCTTCGTGCACTACAAGGATCTGGAACCCGGCAAAT
TCGTCGAGGCCGCCGACTGGGTGGGCCGCGCCGAGGCCGAGGCCGAGGTACTCGCGTCATTCGAGCGTCTCAAGACACAG
GGGCACTAA

Upstream 100 bases:

>100_bases
CGGTGACCATGCTCTGCAGGGTATCGCTATCCTGGTGCGCGCTGGATGAGCGCTTGCGCGAAGACGACTGCCAAGTACCA
CCGACATTCAAGGAGCGGGT

Downstream 100 bases:

>100_bases
CCCGGCATCGGCGCCTGACACACGACGGCGAACACATCGGTGCTTTCCGTCACGGTCACTCCGTCGACGGTGATCGAACA
GCTGATCGTCCCCTCGCCCA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLGEDGDPLDALVLLPESVFPGVIVEARPVGMF
KMVDDGGGDDKVLCVPAGDPRWDHIQDIGDVSSFELDSIKHFFVHYKDLEPGKFVEAADWVGRAEAEAEVLASFERLKTQ
GH

Sequences:

>Translated_162_residues
MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLGEDGDPLDALVLLPESVFPGVIVEARPVGMF
KMVDDGGGDDKVLCVPAGDPRWDHIQDIGDVSSFELDSIKHFFVHYKDLEPGKFVEAADWVGRAEAEAEVLASFERLKTQ
GH
>Mature_162_residues
MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLGEDGDPLDALVLLPESVFPGVIVEARPVGMF
KMVDDGGGDDKVLCVPAGDPRWDHIQDIGDVSSFELDSIKHFFVHYKDLEPGKFVEAADWVGRAEAEAEVLASFERLKTQ
GH

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=159, Percent_Identity=45.9119496855346, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 18204; Mature: 18204

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLGEDGDPLDALV
CCEEEEEECCCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEE
LLPESVFPGVIVEARPVGMFKMVDDGGGDDKVLCVPAGDPRWDHIQDIGDVSSFELDSIK
ECCCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHH
HFFVHYKDLEPGKFVEAADWVGRAEAEAEVLASFERLKTQGH
EEEEEEECCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFDVTIEIPKGQRNKYEVDHETGRVRLDRFLYTPMAYPTDYGFIENTLGEDGDPLDALV
CCEEEEEECCCCCCCCEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEE
LLPESVFPGVIVEARPVGMFKMVDDGGGDDKVLCVPAGDPRWDHIQDIGDVSSFELDSIK
ECCCCCCCCEEEECCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHCCCCCCCHHHHH
HFFVHYKDLEPGKFVEAADWVGRAEAEAEVLASFERLKTQGH
EEEEEEECCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]