| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is dnaX [H]
Identifier: 169627595
GI number: 169627595
Start: 489621
End: 490826
Strand: Direct
Name: dnaX [H]
Synonym: MAB_0491
Alternate gene names: 169627595
Gene position: 489621-490826 (Clockwise)
Preceding gene: 169627593
Following gene: 169627596
Centisome position: 9.66
GC content: 67.91
Gene sequence:
>1206_bases ATGAGCGGGGTTTTCGGGCGCCTGGTGGATCAGGGAGCGGTGGTTTCCACGCTCTCGTCCTCGGCATTGGCTGCACGCGG TGACGATGCGGGGCGAATGACGCACGCATGGTTGTTTACCGGTCCGCCCGGTTCGGGCAGGTCGGTGGCGGCTTTGTGTT TTGCCGCCGCACTTCAGTGCGAATCGGAGGACGTCGCCGGCTGCGGTGCGTGCCGTCCATGCACGACCACGATGGCGGGC ACCCATGCTGACGTGCGCAGAGTGGTGCCGGAGGGGCTCTCGATCGGTGTGGACGAGATGCGTGCCATCGTGCAGGCGGC GTGGCGCAGACCGAGCACGGGACGTTGGTTGGTGGTGCTCATCGAGGACGCCGACCGGTTGACCGAGGGCGCCGGCAATG TGCTGCTGAAGGTCGTCGAGGAGCCGCCGCCTCGGACGGTGTTCCTGTTGTGCGCACCGTCGGTGGACCCCGAGGACATC TCGATTACCCTGCGGTCGCGCTGCCGTCATGTGGCACTCGTCACTCCTTCGGTCGCGGCCATCGCGCAGGTGTTGGTGGA CCGCGATGGCATCGATGCCGAGCAGGCCCAGTGGGCGGCCTCGGTCAGTGGTGGCCACGTGGGCCGGGCCCGCAGACTCG CCACCGATGAGCAGGCGCGTGCGCGTCGGCTTAAGGCGTTGGGGCTGGCGCGGGAGGCAGCCACTCCGAGCCGGGCCTAC GCGGCCGCCGAAGAGCTGGTCACCAGTGCCGATGCCGAGGCCAAGGAGCTGACGGCCGCGCGTAACGAGGCCGAAGAGGA AGAGCTGAAAACCGCGCTGGGGGCGGGCGGCACCGGGAAGGGCGCGGCGACGGCGCTGCGCGGATCCGCCGGCGTCTTGA AAGATCTTGAGCGGAAGCAAAAATCTCGCCAGACCCGGGCCTCACGAGACGCGCTGGACCGTACGCTCATCGATCTGGCG ACCTACTTCCGGGACGCCTTGGTGTTGTCTTTCGGCGCCGCAGGCCAGGGTCGGGTGGCCCTGCATCATCCCGATATGGC CGACAGGCTCGGTCCGATGGTGGACAGAGTGCCGCCCGAGCAGCTGCTGAAGTGCATCGAGGCGGTCCTGGAATGCCGAG AAGCGCTGGCCGTCAATGTGAAGCCCAAGTTCGCGATCGACGCACTGGTCGCGACGGCAGGTCAGGCGTTGCGGCCTTCG GAGTAG
Upstream 100 bases:
>100_bases CAGTCACCCGTTAACCGTAGCTGTCGGCGGTGACGGAGGCGTTTCACACGCCTGTGTGGAGGCGGTTGGAGTCGGTGCCG GCGACTAGGGTTGGTAGGCG
Downstream 100 bases:
>100_bases GTAACGCGATTGGGTCTGCCAGGGTGTCTGCCGTAGACTCTCGGGCGCCGGGTTCGCCCGGCGCGCCACCCTAGCTCAGT CGGTAGAGCAATTCACTCGT
Product: DNA polymerase III subunit delta'
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 401; Mature: 400
Protein sequence:
>401_residues MSGVFGRLVDQGAVVSTLSSSALAARGDDAGRMTHAWLFTGPPGSGRSVAALCFAAALQCESEDVAGCGACRPCTTTMAG THADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVLIEDADRLTEGAGNVLLKVVEEPPPRTVFLLCAPSVDPEDI SITLRSRCRHVALVTPSVAAIAQVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLAREAATPSRAY AAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGAATALRGSAGVLKDLERKQKSRQTRASRDALDRTLIDLA TYFRDALVLSFGAAGQGRVALHHPDMADRLGPMVDRVPPEQLLKCIEAVLECREALAVNVKPKFAIDALVATAGQALRPS E
Sequences:
>Translated_401_residues MSGVFGRLVDQGAVVSTLSSSALAARGDDAGRMTHAWLFTGPPGSGRSVAALCFAAALQCESEDVAGCGACRPCTTTMAG THADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVLIEDADRLTEGAGNVLLKVVEEPPPRTVFLLCAPSVDPEDI SITLRSRCRHVALVTPSVAAIAQVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLAREAATPSRAY AAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGAATALRGSAGVLKDLERKQKSRQTRASRDALDRTLIDLA TYFRDALVLSFGAAGQGRVALHHPDMADRLGPMVDRVPPEQLLKCIEAVLECREALAVNVKPKFAIDALVATAGQALRPS E >Mature_400_residues SGVFGRLVDQGAVVSTLSSSALAARGDDAGRMTHAWLFTGPPGSGRSVAALCFAAALQCESEDVAGCGACRPCTTTMAGT HADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVLIEDADRLTEGAGNVLLKVVEEPPPRTVFLLCAPSVDPEDIS ITLRSRCRHVALVTPSVAAIAQVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLAREAATPSRAYA AAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGAATALRGSAGVLKDLERKQKSRQTRASRDALDRTLIDLAT YFRDALVLSFGAAGQGRVALHHPDMADRLGPMVDRVPPEQLLKCIEAVLECREALAVNVKPKFAIDALVATAGQALRPSE
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]
COG id: COG0470
COG function: function code L; ATPase involved in DNA replication
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786676, Length=182, Percent_Identity=31.8681318681319, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787341, Length=151, Percent_Identity=37.7483443708609, Blast_Score=68, Evalue=9e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR001270 - InterPro: IPR008921 - InterPro: IPR022754 - InterPro: IPR012763 [H]
Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 42235; Mature: 42104
Theoretical pI: Translated: 6.77; Mature: 6.77
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGVFGRLVDQGAVVSTLSSSALAARGDDAGRMTHAWLFTGPPGSGRSVAALCFAAALQC CCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHC ESEDVAGCGACRPCTTTMAGTHADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVL CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE IEDADRLTEGAGNVLLKVVEEPPPRTVFLLCAPSVDPEDISITLRSRCRHVALVTPSVAA ECCCHHHHHCCCHHEEHEECCCCCCEEEEEECCCCCCCCEEEEEHHHCCEEEEECCHHHH IAQVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLAREAATPSRAY HHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH AAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGAATALRGSAGVLKDLERKQ HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHH KSRQTRASRDALDRTLIDLATYFRDALVLSFGAAGQGRVALHHPDMADRLGPMVDRVPPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCHH QLLKCIEAVLECREALAVNVKPKFAIDALVATAGQALRPSE HHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCC >Mature Secondary Structure SGVFGRLVDQGAVVSTLSSSALAARGDDAGRMTHAWLFTGPPGSGRSVAALCFAAALQC CCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHC ESEDVAGCGACRPCTTTMAGTHADVRRVVPEGLSIGVDEMRAIVQAAWRRPSTGRWLVVL CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEE IEDADRLTEGAGNVLLKVVEEPPPRTVFLLCAPSVDPEDISITLRSRCRHVALVTPSVAA ECCCHHHHHCCCHHEEHEECCCCCCEEEEEECCCCCCCCEEEEEHHHCCEEEEECCHHHH IAQVLVDRDGIDAEQAQWAASVSGGHVGRARRLATDEQARARRLKALGLAREAATPSRAY HHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHH AAAEELVTSADAEAKELTAARNEAEEEELKTALGAGGTGKGAATALRGSAGVLKDLERKQ HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHH KSRQTRASRDALDRTLIDLATYFRDALVLSFGAAGQGRVALHHPDMADRLGPMVDRVPPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHCCCHH QLLKCIEAVLECREALAVNVKPKFAIDALVATAGQALRPSE HHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]