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The map label for this gene is yprA [H]

Identifier: 169627590

GI number: 169627590

Start: 481394

End: 483703

Strand: Reverse

Name: yprA [H]

Synonym: MAB_0486c

Alternate gene names: 169627590

Gene position: 483703-481394 (Counterclockwise)

Preceding gene: 169627594

Following gene: 169627587

Centisome position: 9.55

GC content: 65.24

Gene sequence:

>2310_bases
GTGACCGTTGGTTACGGCCGTGAACTGCTGGATCTTATTGTCGCCGGCACGCCGAGCGGCGAGACTCCGGTGCGGCATAT
TTGCGATATCCCTGCCCGAAACGCCGAGGTGACCAGCTGGCCGCAGTGGGCACATCCCGACGCGATAGCCGCATTCGCGG
CTCAAGGTGTGACGGCGCCGTGGTCACACCAGGTCGCCGCCGCCACCCTGGCCTTCGCGGGTCGCCACGTGGTGGTGGCC
ACCGGAACCGCATCTGGCAAGTCGGTCGCGTACCAACTACCGATCCTCACCGCCCTGGCCTCAGAACCGCGCGCACGGGC
GCTGTATCTGGCGCCCACCAAGGCTCTCGGTCACGACCAGTTGCGCGCAGTGCGCGAATTAATCACGGGGGTTGACAATT
TCGAGCGAGTACAGCCGTGCACGTACGACGGCGATAGCTCCAACGAGTTGCGACGGTTCGCCCGGGAAAGCTCCCGCTGG
ATTTTCACCAATCCCGACATGATCCATGTCTCGTTACTGCACAACCACACCCGCTGGTCGGCCTTCCTACGCGGCCTGCG
CTATCTCGTGGTGGACGAATGCCATTACTACCGTGGCGTTTTCGGGTCAAACGTAGCACTGATACTGCAACGTCTGCTAC
GCCTATGCGAGCGCTACGGTTCACATCCGACGGTGGTGTTCGCCAGTGCCACGACTGCCAATCCTGGTGCGGCGGCGCAG
GCCTTGATCGGTCAGCCCGTTGAAGAGGTAGTCGCGGATGGATCACCGCACGGGATGCGCACGGTCGCCCTGTGGGAGCC
ACCCCTGCTGCCGATTACCGGCGAGAACGGGGCACCGGTGCGCCGCCCAGTCAGTACCGAGACGTCGCGGCTGTTGGCCG
ACCTTGTCCAGGAGGGCGCGCGCACGCTTGCCTTCGTCAGGTCGCGGCGTGGCGCGGAGATGACAGCACTAGGCGCCGCG
CATCGGCTGTCCGAGGTCGATCCGGGCCTCGTATCGCAGGTGGCGGCGTACCGGGCCGGTTACCTACCGGAGGACCGGCG
TGCGCTGGAGCAGGCGCTGTCGAGCGGCACGTTGACCGGTGCGGCGACGACGAATGCCCTTGAGCTGGGCGTCGATATCG
CCGGGCTTGATGCCGTGGTGGTGGCGGGGTTCCCGGGTACCGTGGCGTCATTCTGGCAGCAGGCCGGGCGCTCCGGGCGT
CGTGGACAGGGCTCGTTGGTGGTGCTGGTGGCACGCGACGATCCACTGGACACCTACCTGGTGCACCATCCAGAAGCCCT
GCTGGACAAACCGATCGAAGCGGTGGTGATCGACCCTACCAATCCACATGTGCTGCGTCCTCATCTGCTTTGTGCGGCAA
CAGAACTCCCACTCACCGAGGATGATGTACGCTCTCTCGACGCCGGGCAGGTGGTATCCGATCTGGTCGACGACGGGCTG
CTCCGCAAGCGGCCCGGCGGGTATTTCGCAGCACCGGGCCTCAACCCATATGCCGCGGTGGACATCCGAGGGTCGATCGG
CGGGCAGGTCATGATCCTCGAAGCCGACACCGGACGGGTGCTGGGCACGGTCGACACCGGACGCGCTCCGGCGACAGTGC
ATCCGGGTGCGGTCTACCTGCATTCCGGCGAGACATACGTCGTCGATTCACTGGACTTCGGCGACGGAATCGCCCTGGTG
CACAACGACCGGCCCGACTATTCGACGTTCGCGCGCTCCACCATCGATATTGCCATCACCGGCGAGGGCGAGCGGATCGA
CCTGGGTGACATACAGATTGGGCTGGTTCCCGTGGACGTCACCCATCAGGTGATCGGCTATCTACGCACGCTGACAACCG
GGGAGATCCTCGACTTCGTCGAGCTCGACATGCCCTCGTCGACGCTGAGCACCAAGGCGGTGATGTACACCGTCACGCCG
GAAGCATTGGCGGGCATCGATATCGATCCGCTCTCGACCCCCGGCGCCCTACACGCTGCTGAGCACGCCGCGATCGGACT
GCTGCCGTTGGTAGCTAGCTGCGACCGCGGCGATATCGGCGGTGTGTCTACCGCGCTTCAACCGGAGACCGGTCTGCCGA
CGGTATTCGTGTACGACGGCCACCCCGGCGGTGCGGGCTTCGCCGCGCGGGGATACCACAAACTCGCGACCTGGCTGGGC
GCCACGGCCGACGCCATCGACGCCTGCGAATGCGATGCGGGATGCCCATCATGTGTGCAATCACCCAAGTGCGGCAACGG
AAATTCCCCGTTGGACAAGCGCGCTGCCGTCAAGGTACTACGGCTGGTGCTCTCGCGACTGCCGGGCTAG

Upstream 100 bases:

>100_bases
GGCCCCCTTCAGCCCTGCCTTACCCTGGCATTATGGCCATTTACGGTAGCGGGATCGACACCGTTTTGGCACAAGTGTGC
AGGTCACAAGGGGTTTTGCG

Downstream 100 bases:

>100_bases
AACGCCCGCGCGTACTGCTTGGGCACCGCGGGGCTCAGATCCGCACCCAGCTCGCGCGCCGCCCGCCGCGGCCAGTACGG
ATCGCGCAATAGTTCACGGC

Product: DEAD-box ATP dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MTVGYGRELLDLIVAGTPSGETPVRHICDIPARNAEVTSWPQWAHPDAIAAFAAQGVTAPWSHQVAAATLAFAGRHVVVA
TGTASGKSVAYQLPILTALASEPRARALYLAPTKALGHDQLRAVRELITGVDNFERVQPCTYDGDSSNELRRFARESSRW
IFTNPDMIHVSLLHNHTRWSAFLRGLRYLVVDECHYYRGVFGSNVALILQRLLRLCERYGSHPTVVFASATTANPGAAAQ
ALIGQPVEEVVADGSPHGMRTVALWEPPLLPITGENGAPVRRPVSTETSRLLADLVQEGARTLAFVRSRRGAEMTALGAA
HRLSEVDPGLVSQVAAYRAGYLPEDRRALEQALSSGTLTGAATTNALELGVDIAGLDAVVVAGFPGTVASFWQQAGRSGR
RGQGSLVVLVARDDPLDTYLVHHPEALLDKPIEAVVIDPTNPHVLRPHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGL
LRKRPGGYFAAPGLNPYAAVDIRGSIGGQVMILEADTGRVLGTVDTGRAPATVHPGAVYLHSGETYVVDSLDFGDGIALV
HNDRPDYSTFARSTIDIAITGEGERIDLGDIQIGLVPVDVTHQVIGYLRTLTTGEILDFVELDMPSSTLSTKAVMYTVTP
EALAGIDIDPLSTPGALHAAEHAAIGLLPLVASCDRGDIGGVSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLATWLG
ATADAIDACECDAGCPSCVQSPKCGNGNSPLDKRAAVKVLRLVLSRLPG

Sequences:

>Translated_769_residues
MTVGYGRELLDLIVAGTPSGETPVRHICDIPARNAEVTSWPQWAHPDAIAAFAAQGVTAPWSHQVAAATLAFAGRHVVVA
TGTASGKSVAYQLPILTALASEPRARALYLAPTKALGHDQLRAVRELITGVDNFERVQPCTYDGDSSNELRRFARESSRW
IFTNPDMIHVSLLHNHTRWSAFLRGLRYLVVDECHYYRGVFGSNVALILQRLLRLCERYGSHPTVVFASATTANPGAAAQ
ALIGQPVEEVVADGSPHGMRTVALWEPPLLPITGENGAPVRRPVSTETSRLLADLVQEGARTLAFVRSRRGAEMTALGAA
HRLSEVDPGLVSQVAAYRAGYLPEDRRALEQALSSGTLTGAATTNALELGVDIAGLDAVVVAGFPGTVASFWQQAGRSGR
RGQGSLVVLVARDDPLDTYLVHHPEALLDKPIEAVVIDPTNPHVLRPHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGL
LRKRPGGYFAAPGLNPYAAVDIRGSIGGQVMILEADTGRVLGTVDTGRAPATVHPGAVYLHSGETYVVDSLDFGDGIALV
HNDRPDYSTFARSTIDIAITGEGERIDLGDIQIGLVPVDVTHQVIGYLRTLTTGEILDFVELDMPSSTLSTKAVMYTVTP
EALAGIDIDPLSTPGALHAAEHAAIGLLPLVASCDRGDIGGVSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLATWLG
ATADAIDACECDAGCPSCVQSPKCGNGNSPLDKRAAVKVLRLVLSRLPG
>Mature_768_residues
TVGYGRELLDLIVAGTPSGETPVRHICDIPARNAEVTSWPQWAHPDAIAAFAAQGVTAPWSHQVAAATLAFAGRHVVVAT
GTASGKSVAYQLPILTALASEPRARALYLAPTKALGHDQLRAVRELITGVDNFERVQPCTYDGDSSNELRRFARESSRWI
FTNPDMIHVSLLHNHTRWSAFLRGLRYLVVDECHYYRGVFGSNVALILQRLLRLCERYGSHPTVVFASATTANPGAAAQA
LIGQPVEEVVADGSPHGMRTVALWEPPLLPITGENGAPVRRPVSTETSRLLADLVQEGARTLAFVRSRRGAEMTALGAAH
RLSEVDPGLVSQVAAYRAGYLPEDRRALEQALSSGTLTGAATTNALELGVDIAGLDAVVVAGFPGTVASFWQQAGRSGRR
GQGSLVVLVARDDPLDTYLVHHPEALLDKPIEAVVIDPTNPHVLRPHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGLL
RKRPGGYFAAPGLNPYAAVDIRGSIGGQVMILEADTGRVLGTVDTGRAPATVHPGAVYLHSGETYVVDSLDFGDGIALVH
NDRPDYSTFARSTIDIAITGEGERIDLGDIQIGLVPVDVTHQVIGYLRTLTTGEILDFVELDMPSSTLSTKAVMYTVTPE
ALAGIDIDPLSTPGALHAAEHAAIGLLPLVASCDRGDIGGVSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLATWLGA
TADAIDACECDAGCPSCVQSPKCGNGNSPLDKRAAVKVLRLVLSRLPG

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=510, Percent_Identity=27.6470588235294, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320497, Length=779, Percent_Identity=31.5789473684211, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 81400; Mature: 81269

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGYGRELLDLIVAGTPSGETPVRHICDIPARNAEVTSWPQWAHPDAIAAFAAQGVTAP
CCCCCHHHHHHHHEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
WSHQVAAATLAFAGRHVVVATGTASGKSVAYQLPILTALASEPRARALYLAPTKALGHDQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHHCCCCCEEEEEECCHHCCHHH
LRAVRELITGVDNFERVQPCTYDGDSSNELRRFARESSRWIFTNPDMIHVSLLHNHTRWS
HHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEHHCCHHHH
AFLRGLRYLVVDECHYYRGVFGSNVALILQRLLRLCERYGSHPTVVFASATTANPGAAAQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
ALIGQPVEEVVADGSPHGMRTVALWEPPLLPITGENGAPVRRPVSTETSRLLADLVQEGA
HHHCCCHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
RTLAFVRSRRGAEMTALGAAHRLSEVDPGLVSQVAAYRAGYLPEDRRALEQALSSGTLTG
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEC
AATTNALELGVDIAGLDAVVVAGFPGTVASFWQQAGRSGRRGQGSLVVLVARDDPLDTYL
CCCCCEEEECCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE
VHHPEALLDKPIEAVVIDPTNPHVLRPHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGL
EECCHHHHCCCCEEEEECCCCCCEECCHHEEEECCCCCCHHHHHHCCHHHHHHHHHCCCH
LRKRPGGYFAAPGLNPYAAVDIRGSIGGQVMILEADTGRVLGTVDTGRAPATVHPGAVYL
HHCCCCCEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCEECCCEEEE
HSGETYVVDSLDFGDGIALVHNDRPDYSTFARSTIDIAITGEGERIDLGDIQIGLVPVDV
ECCCEEEEECCCCCCCEEEEECCCCCHHHHHCCEEEEEEECCCCEEEECCEEEEEEECCH
THQVIGYLRTLTTGEILDFVELDMPSSTLSTKAVMYTVTPEALAGIDIDPLSTPGALHAA
HHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHH
EHAAIGLLPLVASCDRGDIGGVSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLATWLG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
ATADAIDACECDAGCPSCVQSPKCGNGNSPLDKRAAVKVLRLVLSRLPG
CCHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVGYGRELLDLIVAGTPSGETPVRHICDIPARNAEVTSWPQWAHPDAIAAFAAQGVTAP
CCCCHHHHHHHHEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
WSHQVAAATLAFAGRHVVVATGTASGKSVAYQLPILTALASEPRARALYLAPTKALGHDQ
CCHHHHHHHHHHCCCEEEEEECCCCCCEEEEECHHHHHHHCCCCCEEEEEECCHHCCHHH
LRAVRELITGVDNFERVQPCTYDGDSSNELRRFARESSRWIFTNPDMIHVSLLHNHTRWS
HHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEHHCCHHHH
AFLRGLRYLVVDECHYYRGVFGSNVALILQRLLRLCERYGSHPTVVFASATTANPGAAAQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
ALIGQPVEEVVADGSPHGMRTVALWEPPLLPITGENGAPVRRPVSTETSRLLADLVQEGA
HHHCCCHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
RTLAFVRSRRGAEMTALGAAHRLSEVDPGLVSQVAAYRAGYLPEDRRALEQALSSGTLTG
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEC
AATTNALELGVDIAGLDAVVVAGFPGTVASFWQQAGRSGRRGQGSLVVLVARDDPLDTYL
CCCCCEEEECCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE
VHHPEALLDKPIEAVVIDPTNPHVLRPHLLCAATELPLTEDDVRSLDAGQVVSDLVDDGL
EECCHHHHCCCCEEEEECCCCCCEECCHHEEEECCCCCCHHHHHHCCHHHHHHHHHCCCH
LRKRPGGYFAAPGLNPYAAVDIRGSIGGQVMILEADTGRVLGTVDTGRAPATVHPGAVYL
HHCCCCCEEECCCCCCEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCEECCCEEEE
HSGETYVVDSLDFGDGIALVHNDRPDYSTFARSTIDIAITGEGERIDLGDIQIGLVPVDV
ECCCEEEEECCCCCCCEEEEECCCCCHHHHHCCEEEEEEECCCCEEEECCEEEEEEECCH
THQVIGYLRTLTTGEILDFVELDMPSSTLSTKAVMYTVTPEALAGIDIDPLSTPGALHAA
HHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHH
EHAAIGLLPLVASCDRGDIGGVSTALQPETGLPTVFVYDGHPGGAGFAARGYHKLATWLG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHC
ATADAIDACECDAGCPSCVQSPKCGNGNSPLDKRAAVKVLRLVLSRLPG
CCHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]