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The map label for this gene is katA [H]

Identifier: 169627455

GI number: 169627455

Start: 348158

End: 349621

Strand: Direct

Name: katA [H]

Synonym: MAB_0351

Alternate gene names: 169627455

Gene position: 348158-349621 (Clockwise)

Preceding gene: 169627454

Following gene: 169627456

Centisome position: 6.87

GC content: 61.75

Gene sequence:

>1464_bases
ATGTCCAACCGCACCACAACGAATACCGGAATCGCGGTCGAGAGTGACGACGAGTCGCTGACCGCGGGTACGCAGGGCCC
GGTGTTGCTGCATGACCATTACCTGATCGAGAAGCTTGCCCAGTTCAACCGGGAGCGGGTTCCCGAGCGCATCGTGCACG
CCAAGGGCGCCGGGGCATACGGGGAGCTCGTGATCACCGCCGACGTCTCGAAGTACACCAAGGCGAAGTTGTTCCAGCCC
GGAGCAAAAACCGAATCTTTGGCTCGCTTTTCGACTGTCGCCGGGGAGCAGGGCAGCCCCGATAGCTGGCGCGATCCGCG
CGGATTCGCGGTCAAGTTCTACACCGAAGACGGCAACTACGATCTCGTCGGCAACAACACTCCGGTGTTTTTCATCCGCG
ATGCCATTAAATTCCCGGACTTCATCCGTTCGCAGAAACGGCTGCCCGGTTCCGGGTTGCGTGACCACAACATGCAGTGG
GATTTCTGGACGCTACGGCCCGAGACTGCGCATCAGGTCACCTGGCTGATGGGGGATCGCGGCATTCCGAAGACGTACCG
GCACATGAACGGCTACGGCTCGCACACCTACCAGTGGATCAATGCCGAGGGCGAGCGCTTCTGGGTCAAATACCACTTCA
AGACGGACCAGGGCCATGATTTCCTCACGCAGCAAGAAGCGGATGAGCTTGCGGGCTCGGACGCCGACGCGCATCGCCGC
GATCTGTGGAATGCGATCGAGGACGGCAACTTCCCGAGCTGGACCCTGCACGTACAGGTCATGCCGGTGGACGAAGCGGC
GGGATATCGGTTCAATCCCTTTGATCTGACCAAGGTTTGGTCAAAGAAGGACTACCCGCTGATCGAGGTCGGCAAGTGGA
CGCTCAACCGCAACCCGCGCAACTACTTCGTGGAAATTGAGCAGGCGGCGTTCGAGCCTTCGAATATCGTGCCCGGGATC
GGTTTTTCGCCGGACAAGATGCTGCTGGGCCGGGTGTTCGCCTATGCGGACGCACACCGATACCGCATCGGCACCAACTA
TGCGCAGCTGCCGCCGAATGCGCCGCGCGCCGCAACGGTGAACTCCTATTCCAAGGAGGGGCCGATGCGCTACCACTTCA
ACGATCCGGAAGTTCCCGTCTACGCGCCCAATTCCTTTGGCGGCCCGCACGCCGATCCAGAAGCTGCCGGTGACGGCGGC
GTGTGGGAGTTCGACGGTACGGCAGTGCGCGCCGGGTACATCCAGCATGCGGAGGACGGCGACTTCGTGCAGGCGGGAAC
GTTGGTGCGTGAGGTGCTCGACGACGAGCAGCGTGCGCGACTGGCGGGCAATATCGTCGGACACGTGTTGGACGGAGTCT
CCGAGCCCGTGTTGTCCAGGGTCTTCGAGTACTGGAAGAACGTGGACCCCGAGCTGGGTAAGGCGGTTGAAGAGGGAGTT
CGCGCAGGTCTGGACGCCAAGTAG

Upstream 100 bases:

>100_bases
CGTACCGGGCTTATCTGGTGGTCGACGAGGTGGAAGTCGCCTTCGGGGACGTCTGTCCCCGGTGTCAGTCCAAGTAGTCC
GCTAACGGAGAGGTTTTCTC

Downstream 100 bases:

>100_bases
TCGGAGTGCGGTGAGGTGCCGGTTCCTTCGTTGGGGGACCGGCGTCTTCCGTATGCTCGTTGCATGTCCTACGGCGTACG
TGTGCTCCTCGCGGCAGTTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSNRTTTNTGIAVESDDESLTAGTQGPVLLHDHYLIEKLAQFNRERVPERIVHAKGAGAYGELVITADVSKYTKAKLFQP
GAKTESLARFSTVAGEQGSPDSWRDPRGFAVKFYTEDGNYDLVGNNTPVFFIRDAIKFPDFIRSQKRLPGSGLRDHNMQW
DFWTLRPETAHQVTWLMGDRGIPKTYRHMNGYGSHTYQWINAEGERFWVKYHFKTDQGHDFLTQQEADELAGSDADAHRR
DLWNAIEDGNFPSWTLHVQVMPVDEAAGYRFNPFDLTKVWSKKDYPLIEVGKWTLNRNPRNYFVEIEQAAFEPSNIVPGI
GFSPDKMLLGRVFAYADAHRYRIGTNYAQLPPNAPRAATVNSYSKEGPMRYHFNDPEVPVYAPNSFGGPHADPEAAGDGG
VWEFDGTAVRAGYIQHAEDGDFVQAGTLVREVLDDEQRARLAGNIVGHVLDGVSEPVLSRVFEYWKNVDPELGKAVEEGV
RAGLDAK

Sequences:

>Translated_487_residues
MSNRTTTNTGIAVESDDESLTAGTQGPVLLHDHYLIEKLAQFNRERVPERIVHAKGAGAYGELVITADVSKYTKAKLFQP
GAKTESLARFSTVAGEQGSPDSWRDPRGFAVKFYTEDGNYDLVGNNTPVFFIRDAIKFPDFIRSQKRLPGSGLRDHNMQW
DFWTLRPETAHQVTWLMGDRGIPKTYRHMNGYGSHTYQWINAEGERFWVKYHFKTDQGHDFLTQQEADELAGSDADAHRR
DLWNAIEDGNFPSWTLHVQVMPVDEAAGYRFNPFDLTKVWSKKDYPLIEVGKWTLNRNPRNYFVEIEQAAFEPSNIVPGI
GFSPDKMLLGRVFAYADAHRYRIGTNYAQLPPNAPRAATVNSYSKEGPMRYHFNDPEVPVYAPNSFGGPHADPEAAGDGG
VWEFDGTAVRAGYIQHAEDGDFVQAGTLVREVLDDEQRARLAGNIVGHVLDGVSEPVLSRVFEYWKNVDPELGKAVEEGV
RAGLDAK
>Mature_486_residues
SNRTTTNTGIAVESDDESLTAGTQGPVLLHDHYLIEKLAQFNRERVPERIVHAKGAGAYGELVITADVSKYTKAKLFQPG
AKTESLARFSTVAGEQGSPDSWRDPRGFAVKFYTEDGNYDLVGNNTPVFFIRDAIKFPDFIRSQKRLPGSGLRDHNMQWD
FWTLRPETAHQVTWLMGDRGIPKTYRHMNGYGSHTYQWINAEGERFWVKYHFKTDQGHDFLTQQEADELAGSDADAHRRD
LWNAIEDGNFPSWTLHVQVMPVDEAAGYRFNPFDLTKVWSKKDYPLIEVGKWTLNRNPRNYFVEIEQAAFEPSNIVPGIG
FSPDKMLLGRVFAYADAHRYRIGTNYAQLPPNAPRAATVNSYSKEGPMRYHFNDPEVPVYAPNSFGGPHADPEAAGDGGV
WEFDGTAVRAGYIQHAEDGDFVQAGTLVREVLDDEQRARLAGNIVGHVLDGVSEPVLSRVFEYWKNVDPELGKAVEEGVR
AGLDAK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=51.7970401691332, Blast_Score=490, Evalue=1e-138,
Organism=Escherichia coli, GI48994891, Length=417, Percent_Identity=44.8441247002398, Blast_Score=338, Evalue=7e-94,
Organism=Caenorhabditis elegans, GI71998444, Length=480, Percent_Identity=49.1666666666667, Blast_Score=465, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25147792, Length=475, Percent_Identity=48.8421052631579, Blast_Score=454, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=48.6315789473684, Blast_Score=452, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320462, Length=487, Percent_Identity=44.9691991786448, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=506, Percent_Identity=39.9209486166008, Blast_Score=345, Evalue=1e-95,
Organism=Drosophila melanogaster, GI17981717, Length=483, Percent_Identity=49.0683229813665, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI19920968, Length=483, Percent_Identity=44.3064182194617, Blast_Score=431, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54718; Mature: 54587

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRTTTNTGIAVESDDESLTAGTQGPVLLHDHYLIEKLAQFNRERVPERIVHAKGAGAY
CCCCCCCCCCEEEECCCCCEECCCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHCCCCCCC
GELVITADVSKYTKAKLFQPGAKTESLARFSTVAGEQGSPDSWRDPRGFAVKFYTEDGNY
EEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCE
DLVGNNTPVFFIRDAIKFPDFIRSQKRLPGSGLRDHNMQWDFWTLRPETAHQVTWLMGDR
EEECCCCCEEEEECHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCC
GIPKTYRHMNGYGSHTYQWINAEGERFWVKYHFKTDQGHDFLTQQEADELAGSDADAHRR
CCCHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHH
DLWNAIEDGNFPSWTLHVQVMPVDEAAGYRFNPFDLTKVWSKKDYPLIEVGKWTLNRNPR
HHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECEEEECCCCC
NYFVEIEQAAFEPSNIVPGIGFSPDKMLLGRVFAYADAHRYRIGTNYAQLPPNAPRAATV
EEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCCCCCC
NSYSKEGPMRYHFNDPEVPVYAPNSFGGPHADPEAAGDGGVWEFDGTAVRAGYIQHAEDG
CCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCEEEECEEEECCCC
DFVQAGTLVREVLDDEQRARLAGNIVGHVLDGVSEPVLSRVFEYWKNVDPELGKAVEEGV
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RAGLDAK
HCCCCCC
>Mature Secondary Structure 
SNRTTTNTGIAVESDDESLTAGTQGPVLLHDHYLIEKLAQFNRERVPERIVHAKGAGAY
CCCCCCCCCEEEECCCCCEECCCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHCCCCCCC
GELVITADVSKYTKAKLFQPGAKTESLARFSTVAGEQGSPDSWRDPRGFAVKFYTEDGNY
EEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCE
DLVGNNTPVFFIRDAIKFPDFIRSQKRLPGSGLRDHNMQWDFWTLRPETAHQVTWLMGDR
EEECCCCCEEEEECHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCC
GIPKTYRHMNGYGSHTYQWINAEGERFWVKYHFKTDQGHDFLTQQEADELAGSDADAHRR
CCCHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHH
DLWNAIEDGNFPSWTLHVQVMPVDEAAGYRFNPFDLTKVWSKKDYPLIEVGKWTLNRNPR
HHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHCCCCCCEEEECEEEECCCCC
NYFVEIEQAAFEPSNIVPGIGFSPDKMLLGRVFAYADAHRYRIGTNYAQLPPNAPRAATV
EEEEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCCCCCC
NSYSKEGPMRYHFNDPEVPVYAPNSFGGPHADPEAAGDGGVWEFDGTAVRAGYIQHAEDG
CCCCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEEEECCCEEEECEEEECCCC
DFVQAGTLVREVLDDEQRARLAGNIVGHVLDGVSEPVLSRVFEYWKNVDPELGKAVEEGV
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RAGLDAK
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]