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The map label for this gene is asd [H]

Identifier: 169627448

GI number: 169627448

Start: 341371

End: 342408

Strand: Direct

Name: asd [H]

Synonym: MAB_0344

Alternate gene names: 169627448

Gene position: 341371-342408 (Clockwise)

Preceding gene: 169627447

Following gene: 169627449

Centisome position: 6.74

GC content: 64.45

Gene sequence:

>1038_bases
ATGACCTCCATTGGTGTAGTCGGTGCCACCGGGCAGGTGGGTGCCGTCATGCGGAAGCTTCTGGAAGAGCGTGAGTTCCC
GGCTTCGTCGGTGCGCTTCTTCGCCTCGGCTCGGTCCGAGGGCAAGAAGCTGGCATTCCGCGGCCAGGAGATCGAGGTCG
AGAACACCGAGACGGCCGATCCGTCCGGGCTGGACATCGCGCTGTTCTCCGCCGGGGCCACCATGTCCCGGGTGCAGGCC
CCGCGGTTCGCGCAGGCCGGGGTCACGGTCATCGACAACTCGTCGGCCTGGCGCAAGGATCCGGACGTGCCGTTGGTGGT
CTCGGAGGTCAACTTCGACCGCGACGTGCGCGGGGTGAAACTGCCCAAGGGCATCATCGCCAACCCGAATTGCACGACCA
TGGCCGCGATGCCGGTTTTGAAGGTACTGCACGACGCGGCCGGGCTTACCCGGCTGATCGTGTCGACGTATCAGGCGGTG
TCGGGTAGCGGTTTGGCCGGCGTCGAAGAATTGGCGACCCAGGTGCGGGCCGGTATCGACGGCGGTGAGCAACTGGTACA
TGACGGCACTGCGGTCACCTTCCCCGCTCCCGTGAAATACGTTGCGCCCATTGCTTTTAACGTGATCCCGCTGGCCGGTT
CGTTGGTTGACGACGGCTCCGGTGAAACTGATGAAGACCAGAAGCTGCGCAACGAGAGCCGCAAGATCTTGGGCATTCCG
GAACTTTTGGTGAGCGGGACGTGCGTGCGAGTGCCGGTCTTCACCGGACATTCGCTGTCGATCAATGCCGAGTTCGAACG
TGAGTTGACCCCGGCCCGGGCCACTGAGCTGCTGAGTGCCGCGGCTGGTGTCACGCTCGCCGACGTTCCCACTCCTTTGG
CGGCCGCTGGTGCGGACGACTCTCTGGTCGGCCGGATCCGCCAGGATCCGGGCGTTCCGGGTAATCGTGGTCTGGCGCTG
TTCATTTCCGGAGATAATCTCCGGAAGGGCGCGGCGCTCAACACGATTCAGATCGCGGAACTGCTCGTCGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCAGGCGATCCACAACGCCTTCGATCTCGGGAGCGAAGAGGAAGCCACCGTGTACGCGGGGACCGGGCGCTAGGGCGAG
CGAAGCGACGGGAGATAGAT

Downstream 100 bases:

>100_bases
CTCACGGCAAGTTCACAGGATTTTCGGCGGCGAGCCCAGGCTTACCGGGTCATCCTCGGAGCATGACCAATCCAGAAAAA
TCCGAAAACCCGACCGAACC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTSIGVVGATGQVGAVMRKLLEEREFPASSVRFFASARSEGKKLAFRGQEIEVENTETADPSGLDIALFSAGATMSRVQA
PRFAQAGVTVIDNSSAWRKDPDVPLVVSEVNFDRDVRGVKLPKGIIANPNCTTMAAMPVLKVLHDAAGLTRLIVSTYQAV
SGSGLAGVEELATQVRAGIDGGEQLVHDGTAVTFPAPVKYVAPIAFNVIPLAGSLVDDGSGETDEDQKLRNESRKILGIP
ELLVSGTCVRVPVFTGHSLSINAEFERELTPARATELLSAAAGVTLADVPTPLAAAGADDSLVGRIRQDPGVPGNRGLAL
FISGDNLRKGAALNTIQIAELLVAG

Sequences:

>Translated_345_residues
MTSIGVVGATGQVGAVMRKLLEEREFPASSVRFFASARSEGKKLAFRGQEIEVENTETADPSGLDIALFSAGATMSRVQA
PRFAQAGVTVIDNSSAWRKDPDVPLVVSEVNFDRDVRGVKLPKGIIANPNCTTMAAMPVLKVLHDAAGLTRLIVSTYQAV
SGSGLAGVEELATQVRAGIDGGEQLVHDGTAVTFPAPVKYVAPIAFNVIPLAGSLVDDGSGETDEDQKLRNESRKILGIP
ELLVSGTCVRVPVFTGHSLSINAEFERELTPARATELLSAAAGVTLADVPTPLAAAGADDSLVGRIRQDPGVPGNRGLAL
FISGDNLRKGAALNTIQIAELLVAG
>Mature_344_residues
TSIGVVGATGQVGAVMRKLLEEREFPASSVRFFASARSEGKKLAFRGQEIEVENTETADPSGLDIALFSAGATMSRVQAP
RFAQAGVTVIDNSSAWRKDPDVPLVVSEVNFDRDVRGVKLPKGIIANPNCTTMAAMPVLKVLHDAAGLTRLIVSTYQAVS
GSGLAGVEELATQVRAGIDGGEQLVHDGTAVTFPAPVKYVAPIAFNVIPLAGSLVDDGSGETDEDQKLRNESRKILGIPE
LLVSGTCVRVPVFTGHSLSINAEFERELTPARATELLSAAAGVTLADVPTPLAAAGADDSLVGRIRQDPGVPGNRGLALF
ISGDNLRKGAALNTIQIAELLVAG

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=347, Percent_Identity=31.700288184438, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=26.158038147139, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320362, Length=393, Percent_Identity=26.972010178117, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 35960; Mature: 35829

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIGVVGATGQVGAVMRKLLEEREFPASSVRFFASARSEGKKLAFRGQEIEVENTETAD
CCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCC
PSGLDIALFSAGATMSRVQAPRFAQAGVTVIDNSSAWRKDPDVPLVVSEVNFDRDVRGVK
CCCCEEEEEECCCHHHHHCCCCHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LPKGIIANPNCTTMAAMPVLKVLHDAAGLTRLIVSTYQAVSGSGLAGVEELATQVRAGID
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GGEQLVHDGTAVTFPAPVKYVAPIAFNVIPLAGSLVDDGSGETDEDQKLRNESRKILGIP
CCHHHHHCCCEEECCCCHHHHHHHHHEEEECCCCEECCCCCCCCHHHHHHHHCCEEECCH
ELLVSGTCVRVPVFTGHSLSINAEFERELTPARATELLSAAAGVTLADVPTPLAAAGADD
HHHHCCCEEEEEEEECCEEEECCHHHCCCCHHHHHHHHHHHCCCEEECCCCCHHHCCCCH
SLVGRIRQDPGVPGNRGLALFISGDNLRKGAALNTIQIAELLVAG
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TSIGVVGATGQVGAVMRKLLEEREFPASSVRFFASARSEGKKLAFRGQEIEVENTETAD
CCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCC
PSGLDIALFSAGATMSRVQAPRFAQAGVTVIDNSSAWRKDPDVPLVVSEVNFDRDVRGVK
CCCCEEEEEECCCHHHHHCCCCHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEE
LPKGIIANPNCTTMAAMPVLKVLHDAAGLTRLIVSTYQAVSGSGLAGVEELATQVRAGID
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
GGEQLVHDGTAVTFPAPVKYVAPIAFNVIPLAGSLVDDGSGETDEDQKLRNESRKILGIP
CCHHHHHCCCEEECCCCHHHHHHHHHEEEECCCCEECCCCCCCCHHHHHHHHCCEEECCH
ELLVSGTCVRVPVFTGHSLSINAEFERELTPARATELLSAAAGVTLADVPTPLAAAGADD
HHHHCCCEEEEEEEECCEEEECCHHHCCCCHHHHHHHHHHHCCCEEECCCCCHHHCCCCH
SLVGRIRQDPGVPGNRGLALFISGDNLRKGAALNTIQIAELLVAG
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7910936 [H]