| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is ppsA [H]
Identifier: 169627285
GI number: 169627285
Start: 178481
End: 183829
Strand: Direct
Name: ppsA [H]
Synonym: MAB_0180
Alternate gene names: 169627285
Gene position: 178481-183829 (Clockwise)
Preceding gene: 169627284
Following gene: 169627286
Centisome position: 3.52
GC content: 66.29
Gene sequence:
>5349_bases ATGACTGATACTCAACAGGATTCGACACCAGAGACCAGCCTGGAAACCCCAGCTCCGGAGGTAGCGGCACCGACCGGCGG TGCCGGGCTGACCGTGCCCGAAATGCGCGAATGGCTGCGCAATTGGATCGCCAAGGCCACCGGGGTGAGCCCGGACCGTA TCGACGACTCGGCGCCGATGGTCGAGATGGGTCTGTCCTCACGCGACGCCGTCGCGATGGCCGCCGACATCGAGGACCTC ACCGGGGTCACCCTCACGGCCACCGTGGCCTTTCAGCACCCCACCATCGAGTCGCTGGCCACCCGCATCATCGAGGGCGA GCCCGAGGTGCCGGATGCCGGCGACGAGGACTGGTCGCGCGACCCGAAGATCGCCGCGGGCGAATTCGATATCGCGGTGG TCGGCCTGTCGGCGCGTCTGCCCGGCGACGTCAACAGCCCGGCGCAGCTGTGGGAGGCGCTGCTGGAGGGCCGCGACGCC ATCACCGATCTGCCCGAGGGCCGGTGGGAAGAGTTCACCGCCGAGCCGCGTATTGCCGAGCGTGTGGCTCAGGCCGCCAC CCGCGGTGGATATCTCAAGGACATCAAGGGATTCGACGCCGAGTTCTTCACGCTGTCCAAGATGGAAGCCGACAACATGG ATCCGCAGCAGCGGATCGCGCTGGAATTGACTTGGGAGGCACTGGAAAACGCCCGTATTCCGGCATCCAGCCTCAAGGGT GAGAGCGTCGGTGTGTACATCGGTAGCTCCAACAATGACTACAGCTACTTGTCGGTGGCCGATCCCACCGTCACCCATCC GTACGCCATCACCGGTAACGCGAGTTCGATTATCGCGAACCGGGTTTCGTACTTCTATGACTTCCGTGGCCCGAGCGTCG CCGTCGACACGGCATGTTCCTCGTCGCTGGTCGCGGTGCACCAAGGGGTGAAGGCCCTGCGCTCCGGTGAGGCCGATGTC GTGGTGGCCGGTGGCGTCAACGCACTCATCACGCCTGTGGTGACGGTCGGGTTCGACGAGGTCGGCGGCGTGCTGGCGCC CGATGGCCGGATCAAGTCCTTCTCGCAGGATGCCAACGGGTACAGCCGGTCCGAGGGCGGCGGCATGCTGGTGCTGAAGC GTCTCTCGGACGCGCGCCGCGACGGCGACCCGATCATGGCGATCATCGCGGGTTCGGCCGTCAACCACGACGGACGCTCC AACGGCCTGCTGGCCCCCAACCCGGATGCCCAGGCCGAGGTGCTGCGCAAGGCCTACAAGGACGCCGGAATCGACCCCCG CAGTGTCGATGTCATCGAGGCGCACGGCACCGGCACCATCCTGGGCGACCCGATCGAGGCCGATGGGCTCGGGCGTGTGG TCGGCCGTGGCCGCGACGCCGACAAGCCCGCGCTGCTGGGCTCGGCGAAGTCGAACTTCGGACATCTGGAGTCCGCGGCC GGCGCCGCCAGCCTCTCGAAGATCGTGCTTGCCTTGCAGAACAACAAGGTTCCGCCGTCGATCAACTACACCGGCCCCAA CCCGTATATCGACTTCGACGCGATTCATCTGAAGGTTGTCGATCAGGTCTCCGAATGGCCGCGCTACAGCGGGCACGCCA TCGCGGGCGTCTCCGGCTTCGGTTTCGGTGGAGCCAACGCCCACATCGTGGTGCGCGAAGTGCTGCCGATCGACCTGGTC GAACCCAGCGAAAGCACTGAGCCGGAGTCCGACGACGCCGACACCAACGGCAAACATGCGGTGGCAGAGGCGGATACCGC TGACGGCGACGAATTCTCCGTCTCGCGCTTTGACGAGTACGGCGAGTTCACCGGCGGCTATTCCGATGAGCCGTACGAGC TGCCCGGCCTGACCGATGAGGCCAAGCGGCTCAAGGAAGAGGGGCTGGCGGCGCTCGCTGCCGAAGAGCCGGTCGCTCCG GTTGTGCCGCTGTTCATCTCGGGCTTCCTGTCCTCACGCAAGAAGGCCGCCGCGGCGGCGCTGGCGGACTGGATGGAGAC CGAAGAGGGGCAGTCTTACTCACTGGAGTCCATCGGGCGCTCGTTGTCGCGCCGCAACCATGGCCGCTCCCGCGCCGTGG TGCTGGCCCACGATCACGAGGAGGCCATCAAGGGCCTTCGTGCGGTGGCCGAGGGCAAGCAGAAGCCGTACGTGTACTCC GCGGACGGGCCGGTGAGCAATGGCCCGGTATGGGTGATGGCCGGTTTCGGAGCCCAGCACCGCAAGATGGGCAAGAGCCT GTACCTGCGCGATCCGATCTTCGCCGAGTGGATCGACAAGGTCGACTCGTACGTGCAGGAAGAGCGTGGTTACTCCGTCG TCGAGCTCATCCTCGACGATTCGCACGAGTACGGCATCGAGACCAGTAACATCGCCATCTTCGCGATCCAGATCGGGCTC GGCGAGGTGCTCAAGGCGCATGGCGCCAAGCCCACCGCGGTGATCGGACAGTCGCTGGGCGAGCCCGCGTCGGCCTATTT CGCGGGCGGGCTGTCGCTCGCCGACGCGACACGTGTCATCTGCTCGCGCGCCCATTTGATGGGTGAGGGCGAGGCGATGC TGTTCGGCGACTACATCCGGCTGATGGCGCTGGTCGAATACTCGGCCGACGAACTCAAGACGGTGTTCGCCGACTTCCCC GATCTGGAAGTGTGCGTGTATGCCGCGCCGTCGCAGACCGTCATCGGTGGTCCGCCGGCGCAGGTTGACGCGATAGTGGC CCGCTGCGAGGCGGAAGGCAAGTTCGCGCGCAAGCTGCAGACCAAGGGCGCGGGCCATACGTCGCAGATGGATCCGCTGC TCGGCGAATTCGCCGCCGAACTGCAGGGGATCGAGCCGATGTCCCCGAAGATCGGCATCTTCTCGACGGTCCACGAGGGC ACCTTCATCCGCGGCGGCGGGGAGCCGGTCCACGATGTGGACTACTGGAAGAAGGGGATGCGGCACTCGGTCTACTTCAC CCATGGCACCCGCAACGCCGTGGACGCCGGGCACACCACCTTCCTGGAGCTGGCGCCAAACCCGGTGGCGCTCATGCAGG TTGGGCTAACGACCATGGCGTCGGGGCTGCCGGACGCGCAGCTCATCGCGACCCTCGCCCGCAAGGAGGACGAGGTCGAG TCCATGGTCAAGGCCATGGCGCAGCTGTACGTGCACGGTCACGCGCTGGACCCGCGCACGCTGTTCAGCAGGGCGGCCAA GTCTTCCGACTACGCGCCGATCCCCGCCACCGAGTTCAAACGCAAGCCGCACTGGCTGCCCGCGCATTTCAGTGCCGACG GATCGACCCGCATCCCGGGTACGCATGTGTCGCTGCCCGACGGTAAGCATGTATGGGAGTGGAGTCCGCGGGAGGTCGCC GGCGTCGACTTCGCTGAACTGGTCAAAACCGCTGCGACATCGGTGCTTCCGGGCGCTCAGCTCACCGCGTTTGAGCAGCG CGCCATCCCGGGCGAAGGTTCCACGCTGGTGACCACGCTCTCCCGGCACCCGGGCGGGGCCACCGTGCAGGTGCACGCCC GCATCGGGGAATCGTTCACGCTCGTCTATGACGCGGTGGTGTCGCGTGCCGGTCAGGGTGGCGCACTGCCGTTCGCGACT GCCGCGGGGGTTGCCACCAACGGCAGCGCCGTGGTGAGTGCCTCTGCGGCGCCTTCCCATGCGGTTGCCGTCGTGGAAGA GGAAGTGCCCGAAGAGATTCACGACAACCTGCTGTCCGGAGCAGGCGCGGGCGCCGACTTCAAGAAATGGAGCAAGGAGT CCGGCGAGCCGGTCATCGACCGGTTGGCCACCATCGTGTCGATGGCCATGGGTTACGAGCCCGAGGACGTGCCACGCGAG GTGCCGTTGATCGAGCTGGGTCTGGATTCACTGATGGCCGTGCGGATCAAGAATCGCGTCGAGTTCGACTTCGACCTGCC GCCGATTCAGCTGCAGGCCGTGCGCGACGCGAACCTGCTGGACGTCGAGCGACTGGTCATCTATGCCTTGGAGAACCCGG ACGCCGTGCACGAGTTGCACGACTACCAGCAGACCGACGAGTTCAAGGCGGCCGCGCCGACCGGCGGCATGCTGTCGAAG GCCGATATCGAGGCGGCCCTGACCGCGGGTGCGGCCGAGTCGGTTCCGGCTGAGGTGCCCGCCGCGGAGCCGGCTGCCGA TAGCGCACCCCCCGCCATCGCTCAGGAAGCGACGATCTCGGCGGAGACAAGTGAATTGGCCAAGGCCGCGGCCGCCATGA ACCAGGAAGCCATTGCCGAGGCGCTCAATGCCGATGTGCCGCCGCGTGATGCGGCCGAGCGGGTGGCGTTCGCGACGTGG GCCATCGTCACCGGCGAGTCGCCGGGCAGCATCTTCAACGCACTGCCCAAGATCGACGATGCGACGGCCGAGAAGTTGGC CGAACGTCTGTCGCAGCGCGCTGACGGCGAAATTCCGGCCGAGGAGGTCAAGCTCGCGCCGACCATCGAAGCCCTTGGCG AGGTAGTCCGCAGCAGGCTCGAAGCAGGCAAGATCGACGGCTTTGTGCGGACCCTGGCACCCCGCCAGGAAGGCTCCACG GCGGTTCCCGTATTCGTGTTCCATCCCGCCGGTGGCTCGACCGTCGTCTACGAACCATTGCTGAAGCGTCTGCCCGAGGG CACGCCGATGTTCGGCTTCGAGCGGGTCGAGGGCACCATCGAGGAGCGGGCCGCCAAGTACGTACCCAAGCTGATGGAAC TGCACGACGGCCCGTTCATCCTGGCCGGGTGGTCTCTCGGTGCAGTGCTGGCGTACGCCTGTGCGGTCGGCCTCAAGGAG GCCGGCGCCGAGGTCGCATGGGTCGGCAACATCGACGGTGTACGCCCCGGGACTCCGATCTTGCAGACCAAGGAAGAGAC CCGGAAACGCTGGGACCGTTATGCGGCATTCGCCCAGAAGACGTTCAACGTCGAGATCCCGGCCATCCCGTATGAGCAGC TGGAGGAGCTCGACGACGCGGGCCAGGTGACGTTCGTGCTGGAGGCGGTCAAGGCCAGCGGTGTGCAGATTCCGGGCGGA ATCATCGAGCACCAGCGCACGTCGTATCTCGACCAGCGGGCTATTGACACGTCCACCCCGGTGAAGTTCGACGGGCACAT GACGCTCTACATGGCCGACCGCTACCACGATGACGCCATCACGTTCGAGCCCGCGTACGCGACCCGCCAGCCCGACGGCG GTTGGGGTGAGTTCGTCTCCGACCTCGAGGTCGTTCCGGTCGGCGGTGAGCACATCCAGGTCATCGACGAACCGATCATC GCTAAGGTCGGTGCTCATATGAGTCAGGCGCTGCGGACCATCAACGCCCAACAGGCCCAGCAGGCTTAG
Upstream 100 bases:
>100_bases GCCTGCGCGGCGGCTACCAGCAGACCGCATTCCCCGACGACCGGCAGTAGGCGATCCAGCATCGCCTCGCCATCCGATAC TCCGGAGATAGGCCTCGAAC
Downstream 100 bases:
>100_bases AAAGGTTCAGACACTGTGCCACCACACACAACTGCGGAGAAGCTCGCCGACCTGCGTGAGCGGATTGCGCTCACCCGCGA GCCGGGTGATGCCAAGGCCA
Product: polyketide synthase PKS13
Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 1782; Mature: 1781
Protein sequence:
>1782_residues MTDTQQDSTPETSLETPAPEVAAPTGGAGLTVPEMREWLRNWIAKATGVSPDRIDDSAPMVEMGLSSRDAVAMAADIEDL TGVTLTATVAFQHPTIESLATRIIEGEPEVPDAGDEDWSRDPKIAAGEFDIAVVGLSARLPGDVNSPAQLWEALLEGRDA ITDLPEGRWEEFTAEPRIAERVAQAATRGGYLKDIKGFDAEFFTLSKMEADNMDPQQRIALELTWEALENARIPASSLKG ESVGVYIGSSNNDYSYLSVADPTVTHPYAITGNASSIIANRVSYFYDFRGPSVAVDTACSSSLVAVHQGVKALRSGEADV VVAGGVNALITPVVTVGFDEVGGVLAPDGRIKSFSQDANGYSRSEGGGMLVLKRLSDARRDGDPIMAIIAGSAVNHDGRS NGLLAPNPDAQAEVLRKAYKDAGIDPRSVDVIEAHGTGTILGDPIEADGLGRVVGRGRDADKPALLGSAKSNFGHLESAA GAASLSKIVLALQNNKVPPSINYTGPNPYIDFDAIHLKVVDQVSEWPRYSGHAIAGVSGFGFGGANAHIVVREVLPIDLV EPSESTEPESDDADTNGKHAVAEADTADGDEFSVSRFDEYGEFTGGYSDEPYELPGLTDEAKRLKEEGLAALAAEEPVAP VVPLFISGFLSSRKKAAAAALADWMETEEGQSYSLESIGRSLSRRNHGRSRAVVLAHDHEEAIKGLRAVAEGKQKPYVYS ADGPVSNGPVWVMAGFGAQHRKMGKSLYLRDPIFAEWIDKVDSYVQEERGYSVVELILDDSHEYGIETSNIAIFAIQIGL GEVLKAHGAKPTAVIGQSLGEPASAYFAGGLSLADATRVICSRAHLMGEGEAMLFGDYIRLMALVEYSADELKTVFADFP DLEVCVYAAPSQTVIGGPPAQVDAIVARCEAEGKFARKLQTKGAGHTSQMDPLLGEFAAELQGIEPMSPKIGIFSTVHEG TFIRGGGEPVHDVDYWKKGMRHSVYFTHGTRNAVDAGHTTFLELAPNPVALMQVGLTTMASGLPDAQLIATLARKEDEVE SMVKAMAQLYVHGHALDPRTLFSRAAKSSDYAPIPATEFKRKPHWLPAHFSADGSTRIPGTHVSLPDGKHVWEWSPREVA GVDFAELVKTAATSVLPGAQLTAFEQRAIPGEGSTLVTTLSRHPGGATVQVHARIGESFTLVYDAVVSRAGQGGALPFAT AAGVATNGSAVVSASAAPSHAVAVVEEEVPEEIHDNLLSGAGAGADFKKWSKESGEPVIDRLATIVSMAMGYEPEDVPRE VPLIELGLDSLMAVRIKNRVEFDFDLPPIQLQAVRDANLLDVERLVIYALENPDAVHELHDYQQTDEFKAAAPTGGMLSK ADIEAALTAGAAESVPAEVPAAEPAADSAPPAIAQEATISAETSELAKAAAAMNQEAIAEALNADVPPRDAAERVAFATW AIVTGESPGSIFNALPKIDDATAEKLAERLSQRADGEIPAEEVKLAPTIEALGEVVRSRLEAGKIDGFVRTLAPRQEGST AVPVFVFHPAGGSTVVYEPLLKRLPEGTPMFGFERVEGTIEERAAKYVPKLMELHDGPFILAGWSLGAVLAYACAVGLKE AGAEVAWVGNIDGVRPGTPILQTKEETRKRWDRYAAFAQKTFNVEIPAIPYEQLEELDDAGQVTFVLEAVKASGVQIPGG IIEHQRTSYLDQRAIDTSTPVKFDGHMTLYMADRYHDDAITFEPAYATRQPDGGWGEFVSDLEVVPVGGEHIQVIDEPII AKVGAHMSQALRTINAQQAQQA
Sequences:
>Translated_1782_residues MTDTQQDSTPETSLETPAPEVAAPTGGAGLTVPEMREWLRNWIAKATGVSPDRIDDSAPMVEMGLSSRDAVAMAADIEDL TGVTLTATVAFQHPTIESLATRIIEGEPEVPDAGDEDWSRDPKIAAGEFDIAVVGLSARLPGDVNSPAQLWEALLEGRDA ITDLPEGRWEEFTAEPRIAERVAQAATRGGYLKDIKGFDAEFFTLSKMEADNMDPQQRIALELTWEALENARIPASSLKG ESVGVYIGSSNNDYSYLSVADPTVTHPYAITGNASSIIANRVSYFYDFRGPSVAVDTACSSSLVAVHQGVKALRSGEADV VVAGGVNALITPVVTVGFDEVGGVLAPDGRIKSFSQDANGYSRSEGGGMLVLKRLSDARRDGDPIMAIIAGSAVNHDGRS NGLLAPNPDAQAEVLRKAYKDAGIDPRSVDVIEAHGTGTILGDPIEADGLGRVVGRGRDADKPALLGSAKSNFGHLESAA GAASLSKIVLALQNNKVPPSINYTGPNPYIDFDAIHLKVVDQVSEWPRYSGHAIAGVSGFGFGGANAHIVVREVLPIDLV EPSESTEPESDDADTNGKHAVAEADTADGDEFSVSRFDEYGEFTGGYSDEPYELPGLTDEAKRLKEEGLAALAAEEPVAP VVPLFISGFLSSRKKAAAAALADWMETEEGQSYSLESIGRSLSRRNHGRSRAVVLAHDHEEAIKGLRAVAEGKQKPYVYS ADGPVSNGPVWVMAGFGAQHRKMGKSLYLRDPIFAEWIDKVDSYVQEERGYSVVELILDDSHEYGIETSNIAIFAIQIGL GEVLKAHGAKPTAVIGQSLGEPASAYFAGGLSLADATRVICSRAHLMGEGEAMLFGDYIRLMALVEYSADELKTVFADFP DLEVCVYAAPSQTVIGGPPAQVDAIVARCEAEGKFARKLQTKGAGHTSQMDPLLGEFAAELQGIEPMSPKIGIFSTVHEG TFIRGGGEPVHDVDYWKKGMRHSVYFTHGTRNAVDAGHTTFLELAPNPVALMQVGLTTMASGLPDAQLIATLARKEDEVE SMVKAMAQLYVHGHALDPRTLFSRAAKSSDYAPIPATEFKRKPHWLPAHFSADGSTRIPGTHVSLPDGKHVWEWSPREVA GVDFAELVKTAATSVLPGAQLTAFEQRAIPGEGSTLVTTLSRHPGGATVQVHARIGESFTLVYDAVVSRAGQGGALPFAT AAGVATNGSAVVSASAAPSHAVAVVEEEVPEEIHDNLLSGAGAGADFKKWSKESGEPVIDRLATIVSMAMGYEPEDVPRE VPLIELGLDSLMAVRIKNRVEFDFDLPPIQLQAVRDANLLDVERLVIYALENPDAVHELHDYQQTDEFKAAAPTGGMLSK ADIEAALTAGAAESVPAEVPAAEPAADSAPPAIAQEATISAETSELAKAAAAMNQEAIAEALNADVPPRDAAERVAFATW AIVTGESPGSIFNALPKIDDATAEKLAERLSQRADGEIPAEEVKLAPTIEALGEVVRSRLEAGKIDGFVRTLAPRQEGST AVPVFVFHPAGGSTVVYEPLLKRLPEGTPMFGFERVEGTIEERAAKYVPKLMELHDGPFILAGWSLGAVLAYACAVGLKE AGAEVAWVGNIDGVRPGTPILQTKEETRKRWDRYAAFAQKTFNVEIPAIPYEQLEELDDAGQVTFVLEAVKASGVQIPGG IIEHQRTSYLDQRAIDTSTPVKFDGHMTLYMADRYHDDAITFEPAYATRQPDGGWGEFVSDLEVVPVGGEHIQVIDEPII AKVGAHMSQALRTINAQQAQQA >Mature_1781_residues TDTQQDSTPETSLETPAPEVAAPTGGAGLTVPEMREWLRNWIAKATGVSPDRIDDSAPMVEMGLSSRDAVAMAADIEDLT GVTLTATVAFQHPTIESLATRIIEGEPEVPDAGDEDWSRDPKIAAGEFDIAVVGLSARLPGDVNSPAQLWEALLEGRDAI TDLPEGRWEEFTAEPRIAERVAQAATRGGYLKDIKGFDAEFFTLSKMEADNMDPQQRIALELTWEALENARIPASSLKGE SVGVYIGSSNNDYSYLSVADPTVTHPYAITGNASSIIANRVSYFYDFRGPSVAVDTACSSSLVAVHQGVKALRSGEADVV VAGGVNALITPVVTVGFDEVGGVLAPDGRIKSFSQDANGYSRSEGGGMLVLKRLSDARRDGDPIMAIIAGSAVNHDGRSN GLLAPNPDAQAEVLRKAYKDAGIDPRSVDVIEAHGTGTILGDPIEADGLGRVVGRGRDADKPALLGSAKSNFGHLESAAG AASLSKIVLALQNNKVPPSINYTGPNPYIDFDAIHLKVVDQVSEWPRYSGHAIAGVSGFGFGGANAHIVVREVLPIDLVE PSESTEPESDDADTNGKHAVAEADTADGDEFSVSRFDEYGEFTGGYSDEPYELPGLTDEAKRLKEEGLAALAAEEPVAPV VPLFISGFLSSRKKAAAAALADWMETEEGQSYSLESIGRSLSRRNHGRSRAVVLAHDHEEAIKGLRAVAEGKQKPYVYSA DGPVSNGPVWVMAGFGAQHRKMGKSLYLRDPIFAEWIDKVDSYVQEERGYSVVELILDDSHEYGIETSNIAIFAIQIGLG EVLKAHGAKPTAVIGQSLGEPASAYFAGGLSLADATRVICSRAHLMGEGEAMLFGDYIRLMALVEYSADELKTVFADFPD LEVCVYAAPSQTVIGGPPAQVDAIVARCEAEGKFARKLQTKGAGHTSQMDPLLGEFAAELQGIEPMSPKIGIFSTVHEGT FIRGGGEPVHDVDYWKKGMRHSVYFTHGTRNAVDAGHTTFLELAPNPVALMQVGLTTMASGLPDAQLIATLARKEDEVES MVKAMAQLYVHGHALDPRTLFSRAAKSSDYAPIPATEFKRKPHWLPAHFSADGSTRIPGTHVSLPDGKHVWEWSPREVAG VDFAELVKTAATSVLPGAQLTAFEQRAIPGEGSTLVTTLSRHPGGATVQVHARIGESFTLVYDAVVSRAGQGGALPFATA AGVATNGSAVVSASAAPSHAVAVVEEEVPEEIHDNLLSGAGAGADFKKWSKESGEPVIDRLATIVSMAMGYEPEDVPREV PLIELGLDSLMAVRIKNRVEFDFDLPPIQLQAVRDANLLDVERLVIYALENPDAVHELHDYQQTDEFKAAAPTGGMLSKA DIEAALTAGAAESVPAEVPAAEPAADSAPPAIAQEATISAETSELAKAAAAMNQEAIAEALNADVPPRDAAERVAFATWA IVTGESPGSIFNALPKIDDATAEKLAERLSQRADGEIPAEEVKLAPTIEALGEVVRSRLEAGKIDGFVRTLAPRQEGSTA VPVFVFHPAGGSTVVYEPLLKRLPEGTPMFGFERVEGTIEERAAKYVPKLMELHDGPFILAGWSLGAVLAYACAVGLKEA GAEVAWVGNIDGVRPGTPILQTKEETRKRWDRYAAFAQKTFNVEIPAIPYEQLEELDDAGQVTFVLEAVKASGVQIPGGI IEHQRTSYLDQRAIDTSTPVKFDGHMTLYMADRYHDDAITFEPAYATRQPDGGWGEFVSDLEVVPVGGEHIQVIDEPIIA KVGAHMSQALRTINAQQAQQA
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: COG3321
COG function: function code Q; Polyketide synthase modules and related proteins
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 acyl carrier domains [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=427, Percent_Identity=39.344262295082, Blast_Score=296, Evalue=2e-79, Organism=Homo sapiens, GI8923559, Length=290, Percent_Identity=30, Blast_Score=122, Evalue=4e-27, Organism=Homo sapiens, GI223972627, Length=156, Percent_Identity=31.4102564102564, Blast_Score=74, Evalue=2e-12, Organism=Escherichia coli, GI1787337, Length=435, Percent_Identity=25.9770114942529, Blast_Score=124, Evalue=4e-29, Organism=Escherichia coli, GI1788663, Length=293, Percent_Identity=26.2798634812287, Blast_Score=88, Evalue=4e-18, Organism=Escherichia coli, GI1786801, Length=312, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI212642053, Length=426, Percent_Identity=36.6197183098592, Blast_Score=280, Evalue=6e-75, Organism=Caenorhabditis elegans, GI17550940, Length=504, Percent_Identity=33.1349206349206, Blast_Score=228, Evalue=3e-59, Organism=Caenorhabditis elegans, GI71983541, Length=354, Percent_Identity=24.5762711864407, Blast_Score=108, Evalue=4e-23, Organism=Caenorhabditis elegans, GI71983535, Length=272, Percent_Identity=25.7352941176471, Blast_Score=99, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=24.8322147651007, Blast_Score=118, Evalue=9e-27, Organism=Drosophila melanogaster, GI221330659, Length=430, Percent_Identity=37.4418604651163, Blast_Score=278, Evalue=3e-74, Organism=Drosophila melanogaster, GI19920632, Length=430, Percent_Identity=37.4418604651163, Blast_Score=278, Evalue=3e-74, Organism=Drosophila melanogaster, GI24581345, Length=432, Percent_Identity=37.5, Blast_Score=269, Evalue=1e-71, Organism=Drosophila melanogaster, GI24644341, Length=451, Percent_Identity=29.0465631929047, Blast_Score=145, Evalue=3e-34,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR002198 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020842 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR020806 - InterPro: IPR006162 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 189792; Mature: 189661
Theoretical pI: Translated: 4.47; Mature: 4.47
Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDTQQDSTPETSLETPAPEVAAPTGGAGLTVPEMREWLRNWIAKATGVSPDRIDDSAPM CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCH VEMGLSSRDAVAMAADIEDLTGVTLTATVAFQHPTIESLATRIIEGEPEVPDAGDEDWSR HHHCCCCCCCEEEEECHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC DPKIAAGEFDIAVVGLSARLPGDVNSPAQLWEALLEGRDAITDLPEGRWEEFTAEPRIAE CCCEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCHHHH RVAQAATRGGYLKDIKGFDAEFFTLSKMEADNMDPQQRIALELTWEALENARIPASSLKG HHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHEEEEEEHHHHHCCCCCHHHCCC ESVGVYIGSSNNDYSYLSVADPTVTHPYAITGNASSIIANRVSYFYDFRGPSVAVDTACS CEEEEEECCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHEECCCCCEEEEHHCC SSLVAVHQGVKALRSGEADVVVAGGVNALITPVVTVGFDEVGGVLAPDGRIKSFSQDANG CHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHCCEECCCCCCCCCCCCCCC YSRSEGGGMLVLKRLSDARRDGDPIMAIIAGSAVNHDGRSNGLLAPNPDAQAEVLRKAYK CCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH DAGIDPRSVDVIEAHGTGTILGDPIEADGLGRVVGRGRDADKPALLGSAKSNFGHLESAA HCCCCCCCEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCCCCCEECCCCCCCCHHHHHH GAASLSKIVLALQNNKVPPSINYTGPNPYIDFDAIHLKVVDQVSEWPRYSGHAIAGVSGF HHHHHHHHHHHEECCCCCCCCCCCCCCCCEECCCEEHHHHHHHHHCCCCCCCEEECCCCC GFGGANAHIVVREVLPIDLVEPSESTEPESDDADTNGKHAVAEADTADGDEFSVSRFDEY CCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH GEFTGGYSDEPYELPGLTDEAKRLKEEGLAALAAEEPVAPVVPLFISGFLSSRKKAAAAA HCCCCCCCCCCEECCCCCHHHHHHHHHCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH LADWMETEEGQSYSLESIGRSLSRRNHGRSRAVVLAHDHEEAIKGLRAVAEGKQKPYVYS HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEE ADGPVSNGPVWVMAGFGAQHRKMGKSLYLRDPIFAEWIDKVDSYVQEERGYSVVELILDD CCCCCCCCCEEEEECCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECC SHEYGIETSNIAIFAIQIGLGEVLKAHGAKPTAVIGQSLGEPASAYFAGGLSLADATRVI CHHCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHCCCCHHHHHHCCCHHHHHHHHH CSRAHLMGEGEAMLFGDYIRLMALVEYSADELKTVFADFPDLEVCVYAAPSQTVIGGPPA HHHHHHCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCEECCCCH QVDAIVARCEAEGKFARKLQTKGAGHTSQMDPLLGEFAAELQGIEPMSPKIGIFSTVHEG HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCC TFIRGGGEPVHDVDYWKKGMRHSVYFTHGTRNAVDAGHTTFLELAPNPVALMQVGLTTMA EEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH SGLPDAQLIATLARKEDEVESMVKAMAQLYVHGHALDPRTLFSRAAKSSDYAPIPATEFK CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHC RKPHWLPAHFSADGSTRIPGTHVSLPDGKHVWEWSPREVAGVDFAELVKTAATSVLPGAQ CCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH LTAFEQRAIPGEGSTLVTTLSRHPGGATVQVHARIGESFTLVYDAVVSRAGQGGALPFAT HHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHH AAGVATNGSAVVSASAAPSHAVAVVEEEVPEEIHDNLLSGAGAGADFKKWSKESGEPVID HCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH RLATIVSMAMGYEPEDVPREVPLIELGLDSLMAVRIKNRVEFDFDLPPIQLQAVRDANLL HHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCC DVERLVIYALENPDAVHELHDYQQTDEFKAAAPTGGMLSKADIEAALTAGAAESVPAEVP EEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC AAEPAADSAPPAIAQEATISAETSELAKAAAAMNQEAIAEALNADVPPRDAAERVAFATW CCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHEEEEE AIVTGESPGSIFNALPKIDDATAEKLAERLSQRADGEIPAEEVKLAPTIEALGEVVRSRL EEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHEECCHHHHHHHHHHHHHH EAGKIDGFVRTLAPRQEGSTAVPVFVFHPAGGSTVVYEPLLKRLPEGTPMFGFERVEGTI HHCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHH EERAAKYVPKLMELHDGPFILAGWSLGAVLAYACAVGLKEAGAEVAWVGNIDGVRPGTPI HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC LQTKEETRKRWDRYAAFAQKTFNVEIPAIPYEQLEELDDAGQVTFVLEAVKASGVQIPGG CCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEHEEEHHHHCCEECCCH IIEHQRTSYLDQRAIDTSTPVKFDGHMTLYMADRYHDDAITFEPAYATRQPDGGWGEFVS HHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHC DLEVVPVGGEHIQVIDEPIIAKVGAHMSQALRTINAQQAQQA CCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure TDTQQDSTPETSLETPAPEVAAPTGGAGLTVPEMREWLRNWIAKATGVSPDRIDDSAPM CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCH VEMGLSSRDAVAMAADIEDLTGVTLTATVAFQHPTIESLATRIIEGEPEVPDAGDEDWSR HHHCCCCCCCEEEEECHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCC DPKIAAGEFDIAVVGLSARLPGDVNSPAQLWEALLEGRDAITDLPEGRWEEFTAEPRIAE CCCEECCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCHHHH RVAQAATRGGYLKDIKGFDAEFFTLSKMEADNMDPQQRIALELTWEALENARIPASSLKG HHHHHHHCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHEEEEEEHHHHHCCCCCHHHCCC ESVGVYIGSSNNDYSYLSVADPTVTHPYAITGNASSIIANRVSYFYDFRGPSVAVDTACS CEEEEEECCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHEECCCCCEEEEHHCC SSLVAVHQGVKALRSGEADVVVAGGVNALITPVVTVGFDEVGGVLAPDGRIKSFSQDANG CHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHCCEECCCCCCCCCCCCCCC YSRSEGGGMLVLKRLSDARRDGDPIMAIIAGSAVNHDGRSNGLLAPNPDAQAEVLRKAYK CCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH DAGIDPRSVDVIEAHGTGTILGDPIEADGLGRVVGRGRDADKPALLGSAKSNFGHLESAA HCCCCCCCEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCCCCCEECCCCCCCCHHHHHH GAASLSKIVLALQNNKVPPSINYTGPNPYIDFDAIHLKVVDQVSEWPRYSGHAIAGVSGF HHHHHHHHHHHEECCCCCCCCCCCCCCCCEECCCEEHHHHHHHHHCCCCCCCEEECCCCC GFGGANAHIVVREVLPIDLVEPSESTEPESDDADTNGKHAVAEADTADGDEFSVSRFDEY CCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHH GEFTGGYSDEPYELPGLTDEAKRLKEEGLAALAAEEPVAPVVPLFISGFLSSRKKAAAAA HCCCCCCCCCCEECCCCCHHHHHHHHHCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHH LADWMETEEGQSYSLESIGRSLSRRNHGRSRAVVLAHDHEEAIKGLRAVAEGKQKPYVYS HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCEEEE ADGPVSNGPVWVMAGFGAQHRKMGKSLYLRDPIFAEWIDKVDSYVQEERGYSVVELILDD CCCCCCCCCEEEEECCCHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECC SHEYGIETSNIAIFAIQIGLGEVLKAHGAKPTAVIGQSLGEPASAYFAGGLSLADATRVI CHHCCCCCCCEEEEEEECCHHHHHHHCCCCCHHHHHHHCCCCHHHHHHCCCHHHHHHHHH CSRAHLMGEGEAMLFGDYIRLMALVEYSADELKTVFADFPDLEVCVYAAPSQTVIGGPPA HHHHHHCCCCCEEEHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCEECCCCH QVDAIVARCEAEGKFARKLQTKGAGHTSQMDPLLGEFAAELQGIEPMSPKIGIFSTVHEG HHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCC TFIRGGGEPVHDVDYWKKGMRHSVYFTHGTRNAVDAGHTTFLELAPNPVALMQVGLTTMA EEEECCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHH SGLPDAQLIATLARKEDEVESMVKAMAQLYVHGHALDPRTLFSRAAKSSDYAPIPATEFK CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHC RKPHWLPAHFSADGSTRIPGTHVSLPDGKHVWEWSPREVAGVDFAELVKTAATSVLPGAQ CCCCCCCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH LTAFEQRAIPGEGSTLVTTLSRHPGGATVQVHARIGESFTLVYDAVVSRAGQGGALPFAT HHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHH AAGVATNGSAVVSASAAPSHAVAVVEEEVPEEIHDNLLSGAGAGADFKKWSKESGEPVID HCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHH RLATIVSMAMGYEPEDVPREVPLIELGLDSLMAVRIKNRVEFDFDLPPIQLQAVRDANLL HHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCC DVERLVIYALENPDAVHELHDYQQTDEFKAAAPTGGMLSKADIEAALTAGAAESVPAEVP EEEEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC AAEPAADSAPPAIAQEATISAETSELAKAAAAMNQEAIAEALNADVPPRDAAERVAFATW CCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHEEEEE AIVTGESPGSIFNALPKIDDATAEKLAERLSQRADGEIPAEEVKLAPTIEALGEVVRSRL EEEECCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHEECCHHHHHHHHHHHHHH EAGKIDGFVRTLAPRQEGSTAVPVFVFHPAGGSTVVYEPLLKRLPEGTPMFGFERVEGTI HHCCHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHH EERAAKYVPKLMELHDGPFILAGWSLGAVLAYACAVGLKEAGAEVAWVGNIDGVRPGTPI HHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC LQTKEETRKRWDRYAAFAQKTFNVEIPAIPYEQLEELDDAGQVTFVLEAVKASGVQIPGG CCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCCCEEHEEEHHHHCCEECCCH IIEHQRTSYLDQRAIDTSTPVKFDGHMTLYMADRYHDDAITFEPAYATRQPDGGWGEFVS HHHHHHHHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHC DLEVVPVGGEHIQVIDEPIIAKVGAHMSQALRTINAQQAQQA CCEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: None [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]
Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]