Click here to switch to the map view.

The map label for this gene is pheA

Identifier: 169627237

GI number: 169627237

Start: 129546

End: 130472

Strand: Direct

Name: pheA

Synonym: MAB_0132

Alternate gene names: 169627237

Gene position: 129546-130472 (Clockwise)

Preceding gene: 169627235

Following gene: 169627238

Centisome position: 2.56

GC content: 68.28

Gene sequence:

>927_bases
GTGCAGCGCATCACTTATCTGGGTCCGGAAGGCACGTTTTCGGAGGCCGCAATGATCACGCTGCGTACGACGGGGCGCAT
TCCCGGTTCATCGGAGGTGGAGCCGGTTTCGGTGGCCAGTGCCCGCGAGGCGTTGGTGCAGGTCCAGGCCGGTGACGCCG
ACTATGCGTGCGTCCCGATCGAGAGTTCGCTGGAGGGGCCGGTGGTCCCCACGCTGGACACTCTGGCGGTAGGTGCGCCG
TTGCAAATTTTCGCCGAGACGGTGCTGCCGGTGTCCTTCACCATCGCGGTGCGCCCGGGCACCGCGGCCGGGGATGTAAA
GACCGTCGCAGGGTTCCCGATTGCCGCCGCGCAGGTTCGCGAGTGGCTGGCCACCAATCTGCCGGACGCGGAGCTGGTCG
CCGCGAACTCGAACGCGGCGGCCGCCGAGGATGTGAAGGCCGAGCGGGCCGATGCCGGTGTGTGCACGGAATGGGCCGCA
CAGCGTCTGGGGTTACACGCCCTGGCCAGCGGAGTGGTGGACGAAGCTCATGCGCACACGCGCTTTGTGCTGGTGGGGCG
GCCGGGGCCACCGCCGGCGGCCACCGGGGCGGACCGCACCTCGGTGGTACTGGGGCTGGGAAACGTGCCCGGTGCCCTTG
CCGCCGCCATGAATGAGTTCGCGATCAGAGATATCGACCTGACGCGGATTGAGTCCCGGCCCACCCGCACCGGGCTCGGC
ACGTACCGGTTCTTCCTGGACTGCGTGGGCCATATCGACGACATCGCCGTCGGCGAGGCACTCAAGGGCCTGCATCGGCG
TTGTGAGGATGTGCGGTATTTGGGATCGTGGCCACGAGGGACCACAGCACCTACCGGCGCCAACCCGCCGGTACTGGACG
AAGCGTCGGGATGGCTCGCCGAGACGCGGGAAGGGAGGCTGCGATGA

Upstream 100 bases:

>100_bases
AAGCCTAAGTTAACAACGGACTGTGGAGAGTGCAAGGGACAGCTGTGCCGCAGCCTGTGTCGGGGGTTCGCCCGGCGATC
GAGCGCCTAAGGTTTGAAGT

Downstream 100 bases:

>100_bases
GCGGTCGCCTTGTCTTGGTCAGGCATGGACAGTCCTACGGAAATGTGGAACGCCGGCTGGACACCAAACCACCGGGTGCG
GCGCTGACCGAACTGGGGTT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQRITYLGPEGTFSEAAMITLRTTGRIPGSSEVEPVSVASAREALVQVQAGDADYACVPIESSLEGPVVPTLDTLAVGAP
LQIFAETVLPVSFTIAVRPGTAAGDVKTVAGFPIAAAQVREWLATNLPDAELVAANSNAAAAEDVKAERADAGVCTEWAA
QRLGLHALASGVVDEAHAHTRFVLVGRPGPPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGLG
TYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANPPVLDEASGWLAETREGRLR

Sequences:

>Translated_308_residues
MQRITYLGPEGTFSEAAMITLRTTGRIPGSSEVEPVSVASAREALVQVQAGDADYACVPIESSLEGPVVPTLDTLAVGAP
LQIFAETVLPVSFTIAVRPGTAAGDVKTVAGFPIAAAQVREWLATNLPDAELVAANSNAAAAEDVKAERADAGVCTEWAA
QRLGLHALASGVVDEAHAHTRFVLVGRPGPPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGLG
TYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANPPVLDEASGWLAETREGRLR
>Mature_308_residues
MQRITYLGPEGTFSEAAMITLRTTGRIPGSSEVEPVSVASAREALVQVQAGDADYACVPIESSLEGPVVPTLDTLAVGAP
LQIFAETVLPVSFTIAVRPGTAAGDVKTVAGFPIAAAQVREWLATNLPDAELVAANSNAAAAEDVKAERADAGVCTEWAA
QRLGLHALASGVVDEAHAHTRFVLVGRPGPPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGLG
TYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANPPVLDEASGWLAETREGRLR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain

Homologues:

Organism=Escherichia coli, GI1788951, Length=287, Percent_Identity=26.1324041811847, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHEA_MYCA9 (B1MEG8)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001700886.1
- ProteinModelPortal:   B1MEG8
- SMR:   B1MEG8
- EnsemblBacteria:   EBMYCT00000005938
- GeneID:   5962675
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_0132
- GeneTree:   EBGT00050000015705
- HOGENOM:   HBG693866
- OMA:   CRKWLDA
- ProtClustDB:   PRK11898
- BioCyc:   MABS561007:MAB_0132-MONOMER
- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528

Pfam domain/function: PF01842 ACT; PF00800 PDT

EC number: =4.2.1.51

Molecular weight: Translated: 32179; Mature: 32179

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00857 PREPHENATE_DEHYDR_1; PS00858 PREPHENATE_DEHYDR_2; PS51171 PREPHENATE_DEHYDR_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRITYLGPEGTFSEAAMITLRTTGRIPGSSEVEPVSVASAREALVQVQAGDADYACVPI
CCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHEEEECCCCCEEEEEC
ESSLEGPVVPTLDTLAVGAPLQIFAETVLPVSFTIAVRPGTAAGDVKTVAGFPIAAAQVR
CCCCCCCCCCCHHHHHCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCHHCCCCHHHHHHH
EWLATNLPDAELVAANSNAAAAEDVKAERADAGVCTEWAAQRLGLHALASGVVDEAHAHT
HHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
RFVLVGRPGPPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGLG
EEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCH
TYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANPPVLDEASGWLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
ETREGRLR
HCCCCCCC
>Mature Secondary Structure
MQRITYLGPEGTFSEAAMITLRTTGRIPGSSEVEPVSVASAREALVQVQAGDADYACVPI
CCCEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHEEEECCCCCEEEEEC
ESSLEGPVVPTLDTLAVGAPLQIFAETVLPVSFTIAVRPGTAAGDVKTVAGFPIAAAQVR
CCCCCCCCCCCHHHHHCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCHHCCCCHHHHHHH
EWLATNLPDAELVAANSNAAAAEDVKAERADAGVCTEWAAQRLGLHALASGVVDEAHAHT
HHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
RFVLVGRPGPPPAATGADRTSVVLGLGNVPGALAAAMNEFAIRDIDLTRIESRPTRTGLG
EEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCH
TYRFFLDCVGHIDDIAVGEALKGLHRRCEDVRYLGSWPRGTTAPTGANPPVLDEASGWLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
ETREGRLR
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA