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The map label for this gene is espR [H]

Identifier: 169627220

GI number: 169627220

Start: 115623

End: 116021

Strand: Reverse

Name: espR [H]

Synonym: MAB_0115c

Alternate gene names: 169627220

Gene position: 116021-115623 (Counterclockwise)

Preceding gene: 169627222

Following gene: 169627216

Centisome position: 2.29

GC content: 63.41

Gene sequence:

>399_bases
ATGAGCACCACGTTCACCGCACGTTTGAATCGGTTGTTCGACACCGTGTATCCGCCCGGGCGTGGCCCCCACACCTCTGC
CGAGGTGATCGCGGCCCTGCGGTCCGAGGGCATCACGATGTCCGCCCCGTACCTGTCGCAGCTGCGGTCGGGTAACCGCA
CCAACCCGTCGTCGGCGACCATGAAGGCTCTCGCGAACTTTTTCCGCATCAAGCCGGCGTACTTCACCGATGACGAGTAC
TACGAGAAGCTCGATCAGGAGCTGACCTGGCTCGCGAACATGCGCGACGAGGGCGTTCGCCGGATCGCGGCCCGCACCGT
CGGTCTGTCCGTCGAGGCGCAGGATCGTATTACCCAAACCGTCGACGAATACCGTCGCAAAGAGGGTCTCGACAGCTAG

Upstream 100 bases:

>100_bases
TTGGTGGTTGCGCTTGGCTACAGGCAAAACTAAGGTTACGATGGGCAGCAAATACGTCCCCCGAATTAGCAACTTTATCT
GTTTGTGGAGGTAAGGCTCG

Downstream 100 bases:

>100_bases
TCCACCGCTTGTCTGGCCGGTCCACTCGGGGAAGGACCGGCCAGTTTGGCGTTCACCGCTCGTCGAGCCGGCGGGGGACG
CACAGCGGGACGGGACTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MSTTFTARLNRLFDTVYPPGRGPHTSAEVIAALRSEGITMSAPYLSQLRSGNRTNPSSATMKALANFFRIKPAYFTDDEY
YEKLDQELTWLANMRDEGVRRIAARTVGLSVEAQDRITQTVDEYRRKEGLDS

Sequences:

>Translated_132_residues
MSTTFTARLNRLFDTVYPPGRGPHTSAEVIAALRSEGITMSAPYLSQLRSGNRTNPSSATMKALANFFRIKPAYFTDDEY
YEKLDQELTWLANMRDEGVRRIAARTVGLSVEAQDRITQTVDEYRRKEGLDS
>Mature_131_residues
STTFTARLNRLFDTVYPPGRGPHTSAEVIAALRSEGITMSAPYLSQLRSGNRTNPSSATMKALANFFRIKPAYFTDDEYY
EKLDQELTWLANMRDEGVRRIAARTVGLSVEAQDRITQTVDEYRRKEGLDS

Specific function: Required for secretion and virulence in mice. Activates transcription of an operon that includes espA, espC and espD genes, which are ESX-1 components. Acts by binding directly to the promoter region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Probably secreted via the ESX-1 / type VII secretion system (T7SS) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 14943; Mature: 14812

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTFTARLNRLFDTVYPPGRGPHTSAEVIAALRSEGITMSAPYLSQLRSGNRTNPSSAT
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHCCCCCCCHHHH
MKALANFFRIKPAYFTDDEYYEKLDQELTWLANMRDEGVRRIAARTVGLSVEAQDRITQT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VDEYRRKEGLDS
HHHHHHHCCCCC
>Mature Secondary Structure 
STTFTARLNRLFDTVYPPGRGPHTSAEVIAALRSEGITMSAPYLSQLRSGNRTNPSSAT
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCHHHHHHHCCCCCCCHHHH
MKALANFFRIKPAYFTDDEYYEKLDQELTWLANMRDEGVRRIAARTVGLSVEAQDRITQT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VDEYRRKEGLDS
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]