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The map label for this gene is trpS2 [H]

Identifier: 16767752

GI number: 16767752

Start: 4761826

End: 4762839

Strand: Reverse

Name: trpS2 [H]

Synonym: STM4508

Alternate gene names: 16767752

Gene position: 4762839-4761826 (Counterclockwise)

Preceding gene: 16767755

Following gene: 16767750

Centisome position: 98.05

GC content: 52.96

Gene sequence:

>1014_bases
ATGAACACCCTTCCTATCATTCTGACTGGCGATCGCCCCACCGGCTCGCTGCACCTCGGCCATTATGTCGGTTCACTGCG
CCAGCGCGTCGCGCTACAGCAGGATCACCAACAGTATGTCCTGATTGCCGACCTGCAGGGACTCACCGATAACGGCAGTA
ATCCGCAAAAAATCCGCGATAATATTCCGCAAGTGTTAGCTGACTATCTGGCCGTCGGCATCGATCCCACGCTGACGACG
ATCTGCCTGCAATCCGCGTTACCCGCCCTCGCCGAATTAACGGTGCTGTATATGAATATTGTTACCGTCGCCCGAGTGGA
GCGTAATCCTACGGTAAAAAATGAGATTGCCCAAAAAGGCTTTACCCGTTCCCTGCCGGTCGGGTTCATGGCGTATCCCA
TTAGCCAGGCGGCAGATATCACCGCCTTTAAGGCCGAAATGGTACCGGTTGGCGACGACCAATTGCCCATGATTGAGCAA
ACGAATGAGATCGTTCATAAGATGAATAGTCTTTTCTCCTCGCCGGTATTGCGACCCTGTCAGGCGCTCCTGAGCGATAC
GGGTCGTCTGCCCGGCATTGACGGCAGCGCCAAGATGTCGAAATCGCTCGGCAATACCCTGCTTCTTTCCGCCAGCGAAG
AGACCATCCACCGTGCGGTCAGCGCGATGTACACCGATCCCAATCATTTAAAAATTAGCGATCCGGGAAAAATAGAAGGT
AACGTCGTCTTTACGTGGCTGGATGCGTTTCATCCGGATAAAGCCAAAGTCGCGGCGATGAAAGCACATTATCAACAAGG
CGGATTAGGCGACCGTGTCTGTAAAAATGAGCTGGAGACCTGCCTGCAAGAACTGATCGCGCCCATACGCGAACGACGGG
CAACCTTTATTGCAGATAAGGGAATGCTAATGGAATTACTGAAAAAAGGTAGCGAGCGGGCCCATGAGGTCACTCAAAAG
ACGCTACAGGAAGTAAAACGTGGACTGGGTCTGCCCACGCTATTCCAGGTATAA

Upstream 100 bases:

>100_bases
GGCGGCACGGATCACTATCCCTCTTTAAGTAGCCGCCGAAAGGCGGCTACTGCGTTTCGGGACGTCTTTCGGCTTTACAG
TAAGCATAAAGGAGTCCTTA

Downstream 100 bases:

>100_bases
TCAGGCATCAACGTTGTCCAGCGGCCATGACTCAAACAGATAGCCATCAAAGTAGATGTCATCAACATTGGAAAACTCCA
GCAGACGCTGCTTCACGTTT

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPTLTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV

Sequences:

>Translated_337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPTLTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV
>Mature_337_residues
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPTLTT
ICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQK
TLQEVKRGLGLPTLFQV

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=27.6276276276276, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI41352700, Length=167, Percent_Identity=29.940119760479, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789786, Length=340, Percent_Identity=26.1764705882353, Blast_Score=119, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=26.099706744868, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=26.099706744868, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=25.3561253561254, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24666151, Length=338, Percent_Identity=32.2485207100592, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36956; Mature: 36956

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRD
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
NIPQVLADYLAVGIDPTLTTICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
FTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQTNEIVHKMNSLFSSPVLRPC
CCCCCCCCHHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
QALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
HHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADK
CEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTLFQV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIADLQGLTDNGSNPQKIRD
CCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHH
NIPQVLADYLAVGIDPTLTTICLQSALPALAELTVLYMNIVTVARVERNPTVKNEIAQKG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
FTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQTNEIVHKMNSLFSSPVLRPC
CCCCCCCCHHHHCCHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
QALLSDTGRLPGIDGSAKMSKSLGNTLLLSASEETIHRAVSAMYTDPNHLKISDPGKIEG
HHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCC
NVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKNELETCLQELIAPIRERRATFIADK
CEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTLFQV
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA