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The map label for this gene is arcB [H]

Identifier: 16767710

GI number: 16767710

Start: 4707266

End: 4708270

Strand: Reverse

Name: arcB [H]

Synonym: STM4465

Alternate gene names: 16767710

Gene position: 4708270-4707266 (Counterclockwise)

Preceding gene: 16767711

Following gene: 16767709

Centisome position: 96.93

GC content: 55.52

Gene sequence:

>1005_bases
ATGGTTATTTCACTGAAAAATCGTAACTTTTTGAAGCTGCTTGACTACACCCCGGCGGAAATCCAACACCTCATCGATCT
GGCTATTGAGCTGAAAGCCGCAAAAAAAGCCGGATGCGAAAAGCAAACACTGATCGGCAAAAACATCGCGCTGATTTTTG
AAAAAACCTCTACTCGCACCCGATGCGCGTTTGAAGTCGCCGCGTTCGACCAGGGCGCGCAGGTGACTTATCTCGGCCCA
AGCGGCTCGCAGATCGGCCATAAAGAGTCCATGAAAGATACTGCTCGCGTCCTGGGGCGGATGTATGACGGCATCGAATA
TCGCGGATTTGGTCAACACATTGTGGAAGAGCTGGGGGAATACGCGGGCGTTCCCGTCTGGAACGGCCTGACCGATGAAT
TTCACCCCACACAGATCCTGGCCGATCTGATGACCATGCTGGAACATGCGCCGGGCAAAACGCTGCCGGAACTGAGCTTC
GCCTACCTGGGCGACGCGCGCAACAACATGGGCAATTCGCTGATGGTGGGCGCGGCGAAGATGGGCATGGATATCCGTCT
GATAGCGCCAAAGTCCTTCTGGCCTGATGCCGCGCTGGTCGCGCAGTGCCGAGAAATCGCCAGCGTTACCGGCGCTCGTA
TCACCTTAACGGAGAGCGTTGAAGACGGCGTTCACGGTGTGGATTTCCTCTATACCGACGTCTGGGTCTCGATGGGAGAA
CCCAAAGAAGCCTGGGCGGAGCGCGTCAGTCTGATGACGCCATATCAGGTCAACCAGCAGGTGGTAAACGCTACCGGTAA
TCCTGATGTGAAGTTTATGCACTGCCTGCCCGCCTTCCATAACGAGCACACCAAAGTGGGACGCGAAATCGAAATGGCTT
ACGGCCTGAAAGGACTGGAGGTCACGGAAGAGGTGTTCGAGTCCGCAGGCTCGATAGTCTTCGATGAAGCGGAAAACCGG
ATGCACACCATCAAAGCAGTCATGGTGGCGACGCTCGGCGACTAA

Upstream 100 bases:

>100_bases
GGATGGCGGCTTCCGCCTTATTCGGCCTACAGAGCGCGCATAACCGTGGGCCGGATAAGCGCAGCGCCATCAGGCAATTC
ATTTTAACAAGGATATTGTA

Downstream 100 bases:

>100_bases
TCCCACAGGATATGCGCCCTCGCGGCGCATATCCGTGATATCAGGAGAGAACATCATGGGTAAATTTAAATTTCCCACCG
CTTATACCATCCTGTTTATT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGEYAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSF
AYLGDARNNMGNSLMVGAAKMGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGE
PKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLEVTEEVFESAGSIVFDEAENR
MHTIKAVMVATLGD

Sequences:

>Translated_334_residues
MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGEYAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSF
AYLGDARNNMGNSLMVGAAKMGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGE
PKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLEVTEEVFESAGSIVFDEAENR
MHTIKAVMVATLGD
>Mature_334_residues
MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGP
SGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGEYAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSF
AYLGDARNNMGNSLMVGAAKMGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGE
PKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLEVTEEVFESAGSIVFDEAENR
MHTIKAVMVATLGD

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=333, Percent_Identity=37.2372372372372, Blast_Score=201, Evalue=5e-52,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=68.5015290519878, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=67.6737160120846, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI48994908, Length=378, Percent_Identity=24.8677248677249, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI2367364, Length=297, Percent_Identity=28.6195286195286, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=329, Percent_Identity=32.8267477203647, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322331, Length=293, Percent_Identity=25.2559726962457, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 36817; Mature: 36817

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRT
CEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCC
RCAFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGE
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHCCCCCEEEEEHHH
MGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGE
HCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHHHHHHHHHHCCCC
PKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLE
CHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHCCEEHHHHCCCCCH
VTEEVFESAGSIVFDEAENRMHTIKAVMVATLGD
HHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTLIGKNIALIFEKTSTRT
CEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEEECCCCCC
RCAFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMYDGIEYRGFGQHIVEELGE
EEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSFAYLGDARNNMGNSLMVGAAK
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHCCCCCEEEEEHHH
MGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTESVEDGVHGVDFLYTDVWVSMGE
HCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHHHHHHHHHHCCCC
PKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCLPAFHNEHTKVGREIEMAYGLKGLE
CHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEHHHHCCCHHHHCCEEHHHHCCCCCH
VTEEVFESAGSIVFDEAENRMHTIKAVMVATLGD
HHHHHHHCCCCEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]