Definition Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome.
Accession NC_003197
Length 4,857,432

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The map label for this gene is yjeM

Identifier: 16767594

GI number: 16767594

Start: 4587298

End: 4588800

Strand: Direct

Name: yjeM

Synonym: STM4345

Alternate gene names: 16767594

Gene position: 4587298-4588800 (Clockwise)

Preceding gene: 16767593

Following gene: 16767595

Centisome position: 94.44

GC content: 48.57

Gene sequence:

>1503_bases
ATGACCCACACGATAAAAAAGATGAGCCTTATTGGGCTTATCCTGATGATTTTTACTTCTGTTTTTGGTTTTGCGAATAG
CCCGTCGGCGTTTTATTTAATGGGGTATAGCGCAATCCCATGGTATATATTTTCTGCCTTGCTGTTTTTTATTCCATTCG
CCTTAATGATGGCTGAAATGGGTTCCGCTTATCGCAAAGAAGAGGGCGGGATCTATTCGTGGATGAATAATAGCGTGGGG
CCACGTTACGCGTTTATTGGCACGTTTATGTGGTTTTCATCGTATGTCATATGGATGGTAAGTACGGCGGCAAAAATTTG
GGTACCGTTTTCTACTTTTGTTTTTGGCGCCGATATGACGCAGCACTGGCGTATTGCAGGGCTTGAGCCTACGCAGGTTG
TCGGGCTGCTCGCCGTCGGCTGGATGATTCTGGTGACGTGTGTCGCCGCCAGAGGGATCAATAAAATTGCGCGAATTACG
GCGGTCGGAGGTATTGCCGTAATGTGTCTTAATTTAGTTTTATTGTTAGTGAGTGTCGCTATTTTGTTATTAAATGGTGG
GCATTTTGCACAAGAAATTAATTTTACCTCGTCACCGAATCCGGGTTATCACTCCGGCCTGGCAATGTTGTCATTTGTGG
TATTTGCTATTTTTGCGTACGGCGGTATTGAGGCTGTCGGCGGACTGGTGGATAAAACCGAGAAACCGGAAAAGAATTTT
GCGAAAGGTATTGTTTTCGCGGCTATTGTGATTTCAATTGGTTATTCTTTGGCGATCTTTTTATGGGGCGTCAGCACTAA
CTGGCAACAGATATTAAGTAATAGCGCCGTTAACTTAGGGAATATCACCTACATTCTGATGTCGAGTTTAGGCACGACAT
TAGGTAACGCGTTAAACCTTTCTCCGGAAGCAGCGATGACGGTGGGCGTCTGGTTTGCGCGTATCACCGGCCTTTCTATG
TTTCTGGCTTATACCGGCGCGTTTTTTACGTTGAGCTATTCACCGCTGAAAGCCATTATTCAGGGGACGCCAAAAGCGTT
GTGGCCCGCGCCGATGACGACACTGAACGCTAACGGTATGCCGGCGACCGCTATGTGGCTACAGTGCGTGCTGGTGAGTC
TGTTTATTTTGCTGGTCTCTTTTGGCGGTGACACCGCATCGGCGTTTTATAACAAACTCACGCTGATGGCGAACGTCTCA
ATGACCTTGCCATACCTGTTCCTTGCGCTGGCATTTCCCTTCTTTAAAGCGCGTCAGGATCTGGAGCGGCCATTTGTTCT
CTTTAAAACCAAAGCCTCTACCCTGGTCGCGACGGGTGTTGTGGTGCTGGTGGTGACGTTTGCCAACGTCTTTACCATCA
TCCAGCCAGTGATTGAAGCTGGGGACTGGGACAGCGCCTTGTGGATGATCGGCGGCCCGATCTTCTTCTCGCTGCTGGCG
ATGGCGATTTATCAGAATTACAGTAGCCGCATGAGCGCCGATCCGGAGTGGGCGGCGGAGTAA

Upstream 100 bases:

>100_bases
CCTGTGTTGATTTTTTTATCGCTGACCTTCGTAAAAAAGAAGGCGGCGTCAATCGGTGAGCGGCGTCTGGCAAACGCGCT
CGAGCGTAAGGGATGGTTGA

Downstream 100 bases:

>100_bases
TCTTTGTCCGGATAGCGTTAGCTCATCGGCTTTATGAAAAGGATATTTATAATGAGTCCGAAAATGTTTGCGTTGTGCGC
TATCTGGATTTTACTGGCTA

Product: amino-acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTHTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIFSALLFFIPFALMMAEMGSAYRKEEGGIYSWMNNSVG
PRYAFIGTFMWFSSYVIWMVSTAAKIWVPFSTFVFGADMTQHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARIT
AVGGIAVMCLNLVLLLVSVAILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIFAYGGIEAVGGLVDKTEKPEKNF
AKGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSAVNLGNITYILMSSLGTTLGNALNLSPEAAMTVGVWFARITGLSM
FLAYTGAFFTLSYSPLKAIIQGTPKALWPAPMTTLNANGMPATAMWLQCVLVSLFILLVSFGGDTASAFYNKLTLMANVS
MTLPYLFLALAFPFFKARQDLERPFVLFKTKASTLVATGVVVLVVTFANVFTIIQPVIEAGDWDSALWMIGGPIFFSLLA
MAIYQNYSSRMSADPEWAAE

Sequences:

>Translated_500_residues
MTHTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIFSALLFFIPFALMMAEMGSAYRKEEGGIYSWMNNSVG
PRYAFIGTFMWFSSYVIWMVSTAAKIWVPFSTFVFGADMTQHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARIT
AVGGIAVMCLNLVLLLVSVAILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIFAYGGIEAVGGLVDKTEKPEKNF
AKGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSAVNLGNITYILMSSLGTTLGNALNLSPEAAMTVGVWFARITGLSM
FLAYTGAFFTLSYSPLKAIIQGTPKALWPAPMTTLNANGMPATAMWLQCVLVSLFILLVSFGGDTASAFYNKLTLMANVS
MTLPYLFLALAFPFFKARQDLERPFVLFKTKASTLVATGVVVLVVTFANVFTIIQPVIEAGDWDSALWMIGGPIFFSLLA
MAIYQNYSSRMSADPEWAAE
>Mature_499_residues
THTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIFSALLFFIPFALMMAEMGSAYRKEEGGIYSWMNNSVGP
RYAFIGTFMWFSSYVIWMVSTAAKIWVPFSTFVFGADMTQHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARITA
VGGIAVMCLNLVLLLVSVAILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIFAYGGIEAVGGLVDKTEKPEKNFA
KGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSAVNLGNITYILMSSLGTTLGNALNLSPEAAMTVGVWFARITGLSMF
LAYTGAFFTLSYSPLKAIIQGTPKALWPAPMTTLNANGMPATAMWLQCVLVSLFILLVSFGGDTASAFYNKLTLMANVSM
TLPYLFLALAFPFFKARQDLERPFVLFKTKASTLVATGVVVLVVTFANVFTIIQPVIEAGDWDSALWMIGGPIFFSLLAM
AIYQNYSSRMSADPEWAAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Escherichia coli, GI87082380, Length=500, Percent_Identity=87.4, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI87081798, Length=430, Percent_Identity=22.5581395348837, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI48994921, Length=505, Percent_Identity=23.960396039604, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787768, Length=475, Percent_Identity=25.6842105263158, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJEM_SALTI (P0A2N5)

Other databases:

- EMBL:   AL627283
- EMBL:   AE014613
- RefSeq:   NP_458784.1
- RefSeq:   NP_807988.1
- GeneID:   1068211
- GeneID:   1250906
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t4397
- KEGG:   sty:STY4705
- HOGENOM:   HBG416814
- OMA:   FANIFTI
- ProtClustDB:   PRK15238
- BioCyc:   SENT209261:T4397-MONOMER
- BioCyc:   SENT220341:STY4705-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 54461; Mature: 54330

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13ad0ff4)-; HASH(0x137190c8)-; HASH(0x13450f88)-; HASH(0x143f1898)-; HASH(0xd64d2f0)-; HASH(0x4217ad58)-; HASH(0x134236ec)-; HASH(0x1284cb34)-; HASH(0x421c1d08)-; HASH(0x137055cc)-; HASH(0x143f3508)-; HASH(0x143f176c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTHTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIFSALLFFIPFALMMAEM
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GSAYRKEEGGIYSWMNNSVGPRYAFIGTFMWFSSYVIWMVSTAAKIWVPFSTFVFGADMT
HHHHHHHCCCEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHCCCCCC
QHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARITAVGGIAVMCLNLVLLLVSVA
CCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIFAYGGIEAVGGLVDKTEKPEKNF
HHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHH
AKGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSAVNLGNITYILMSSLGTTLGNALNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCC
SPEAAMTVGVWFARITGLSMFLAYTGAFFTLSYSPLKAIIQGTPKALWPAPMTTLNANGM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCCCCCCCCCEECCCCC
PATAMWLQCVLVSLFILLVSFGGDTASAFYNKLTLMANVSMTLPYLFLALAFPFFKARQD
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LERPFVLFKTKASTLVATGVVVLVVTFANVFTIIQPVIEAGDWDSALWMIGGPIFFSLLA
HCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHH
MAIYQNYSSRMSADPEWAAE
HHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
THTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIFSALLFFIPFALMMAEM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504