Click here to switch to the map view.

The map label for this gene is dinF [H]

Identifier: 16767488

GI number: 16767488

Start: 4460035

End: 4461360

Strand: Direct

Name: dinF [H]

Synonym: STM4238

Alternate gene names: 16767488

Gene position: 4460035-4461360 (Clockwise)

Preceding gene: 16767487

Following gene: 16767489

Centisome position: 91.82

GC content: 57.01

Gene sequence:

>1326_bases
ATGCCGCTTTTTACCTCCTCTGATAAAGCTCTCTGGCGTCTTGCGTTGCCGATGATTTTTTCTAACATCACCGTCCCCTT
ACTGGGGCTGGTCGATACGGCGGTGATTGGTCATCTGGACAGCCCTGTTTTCCTGGGCGGCGTGGCGGTGGGCGCGACTG
CCACCAGCTTTCTTTTCATGCTGCTGCTATTTCTACGTATGAGCACCACCGGCCTAACGGCGCAGGCATTTGGCGCCAAA
AATCCGCAGGCGTTAGCCCGGGCGCTCATTCAACCGTTATTGCTGGCGCTGGGCGCAGGCGTGATGATTGTGCTATTTCG
CACGCCGCTTATCGAGCTGGCTTTACATATTGTCGGCGGGAACGACGCTGTCCTGGTGCAGGCGAGACGCTTCCTTGAAA
TTCGTTGGCTAAGCGCTCCCGCGTCACTGGCGAATCTGGTGCTGCTCGGTTGGCTGTTAGGCGTTCAGTATGCGCGGGCG
CCGGTTATCTTGTTGGTCGTGGGCAATATCCTCAATATCGCGCTCGACCTGTGGCTGGTGATGGGGCTTCATATGAACGT
GCAGGGTGCTGCCCTGGCGACGGTCATCGCAGAATATGTCACGTTACTGATCGGCCTCATGATGGTACGTAAAGTTCTCC
ATCTCCGCGGTGTGTCGCTGGATATGCTAAAACAGGCCTGGCGCGGCAACGTGCGCCGCCTTTTGGCGCTCAATCGCGAT
ATCATGCTGCGCTCATTGCTCCTTCAGCTTTGTTTTGGCGCAATCACGGTGTCAGGCGCGCGGCTGGGCAGCGATATTAT
CGCGGTAAATGCAGTCCTGATGACCTTACTCACCTTTACGGCCTATGCGCTGGACGGTTTTGCTTATGCGGTGGAGGCGC
ACTCCGGTCAGGCTTACGGCGCGCGTGACGGTAGCAAGCTACTGGACGTCTGGCGAGCGGCGTGTCGTCAGTCAGGAATT
GTGGCCTTGTTGTTTTCCACAGTCTATGCCCTGGCAGGCGAACATATTGTCGCGTTACTGACCTCATTGCCGCAAATACA
GCTACTGGCGGATCGGTATCTTATCTGGCAGGTGGTATTACCGCTGGTGGGCGTATGGTGCTATCTGCTCGACGGTATGT
TTATTGGCGCGACGCGCGCTGCCGAAATGCGCAATAGCATGGCAGTCGCCGCGGGAGGATTCGCGCTGACGCTCTTCGCC
CTGCCGGTATTAGGAAATCATGGTTTATGGCTGGCATTAACCGTGTTCCTGGCGCTTCGCGGTCTGTCGTTGAGCCTTAT
CTGGCGTCGTCACTGGCGCGAGGGTACATGGTTTGCCAGATCGTGA

Upstream 100 bases:

>100_bases
AATGCAGTTCCTGAGATGATTAATTTGTAGGCCGGATAAGGCGTTACGTCGCATCCGGCAATGCGCTCGTTTCGTTTAAC
TCCTTGTCAGGCTTTTCTCC

Downstream 100 bases:

>100_bases
CGGTTAAAAATTCTGAATATAAAACCGAAGGCCGAATTCCTGCCTACAATTATTATCACGTCCAGCAGAAATTGCAGAGC
ATTTGGGCGAATAACACCTG

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK
NPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI
VALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFA
LPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS

Sequences:

>Translated_441_residues
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAK
NPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGI
VALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFA
LPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS
>Mature_440_residues
PLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKN
PQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP
VILLVVGNILNIALDLWLVMGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRDI
MLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIV
ALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFAL
PVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=439, Percent_Identity=89.5216400911162, Blast_Score=711, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47766; Mature: 47635

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
LLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGG
HHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
NDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALDLWLV
CCEEEHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSKLLDVWRAACRQSGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFALPVLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLSLSLIWRRHWREGTWFARS
CCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVFLGGVAVGATATSFLFM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHH
LLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVMIVLFRTPLIELALHIVGG
HHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
NDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIALDLWLV
CCEEEHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
MGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGVSLDMLKQAWRGNVRRLLALNRD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSKLLDVWRAACRQSGIVALLFSTVYALAGEHIVALLTSLPQIQLLADRYLIWQVVL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAGGFALTLFALPVLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHCHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLSLSLIWRRHWREGTWFARS
CCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]