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The map label for this gene is yiaY [H]

Identifier: 16767310

GI number: 16767310

Start: 4253807

End: 4254955

Strand: Reverse

Name: yiaY [H]

Synonym: STM4044

Alternate gene names: 16767310

Gene position: 4254955-4253807 (Counterclockwise)

Preceding gene: 16767311

Following gene: 16767309

Centisome position: 87.6

GC content: 57.79

Gene sequence:

>1149_bases
ATGAGCTTTATGTTGGCACTGCCAAAAATTAGCCTGCATGGCGCTGGAGCGATTGCCGATATGGTGAACCTCGTGGCGAA
TAAGCAATGGGGCAAAGCGCTGATCGTTACCGATGGTCAACTGGTAAAGCTGGGCCTGCTGGATAGCCTGTTTAGCGCAC
TGGATGAACATCAAATGTCTTACCACCTGTTTGATGAGGTGTTCCCAAACCCGACAGAAGAGCTGGTGCAGAAAGGTTTT
GCGGCGTATCAGAGCGCAGAATGTGACTACATTATCGCCTTCGGCGGCGGCAGCCCGATCGATACCGCAAAAGCGGTGAA
AATCCTCACCGCCAACCCTGGCCCTTCCACCGCCTACTCCGGCGTCGGCAAAGTGAAAAACGCCGGCGTACCGCTGGTAG
CGATTAATACTACGGCAGGTACCGCGGCCGAGATGACCAGCAACGCGGTGATTATCGACTCTGCCCGTAAGGTCAAAGAG
GTGATCATCGACCCGAATATCATCCCGGATATTGCCGTGGATGACGCCAGCGTCATGCTGGAAATCCCGGCGTCTGTGAC
CGCCGCAACCGGCATGGATGCCCTGACCCATGCGGTGGAAGCCTATGTCTCCGTTGGCGCGCATCCGCTTACCGACGCTA
ACGCGCTGGAAGCGATTCGCTTAATCAATTTGTGGCTACCGAAAGCGGTTGACGATGGCCATAACCTCGAAGCCCGTGAG
CAAATGGCATTCGGCCAGTACCTGGCGGGTATGGCGTTCAACAGCGCCGGTTTGGGGCTGGTTCACGCGCTGGCGCACCA
GCCGGGCGCAACTCACAACCTGCCGCACGGCGTCTGCAACGCTATCCTGCTGCCAATTGTCGAGAACTTTAACCGTCCGA
ACGCCGTCGCGCGTTTTGCCCGTATCGCACAGGCGATGGGCGTAGAGACGCGCGGTATGTCTGACGAAGCCGCAAGTCAG
GAAGCGATTAACGCTATCCGTACGCTGAGCAAACGCGTCGGCATTCCAGAAGGTTTCAGCAAGCTGGGCGTCACAAAAGA
AGATATCGAAGGCTGGCTGGATAAAGCCCTCGCCGACCCGTGCGCGCCGTGTAACCCGCGCACCGCCAGCCGCGATGAAG
TTCGCGGGCTGTACCTGGAGGCGTTATGA

Upstream 100 bases:

>100_bases
GCTTTGCCTTATCCGGCCTACAGGACGGTGCGCATTTTACCGTAGGCCCGATAAGCGTAGCGCCATCGGGCAACAGGGAA
TTTTTTTAAGGAGAATAGTG

Downstream 100 bases:

>100_bases
TCCGCAAAGCCTTTGTGATGCAGGTAAATGCCGACGCGCACGAGGAGTATCAGCGTCGTCATAACCCAATCTGGCCGGAG
CTGGAAGCCGTATTAAAATC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKLGLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGF
AAYQSAECDYIIAFGGGSPIDTAKAVKILTANPGPSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKE
VIIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEAIRLINLWLPKAVDDGHNLEARE
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIVENFNRPNAVARFARIAQAMGVETRGMSDEAASQ
EAINAIRTLSKRVGIPEGFSKLGVTKEDIEGWLDKALADPCAPCNPRTASRDEVRGLYLEAL

Sequences:

>Translated_382_residues
MSFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKLGLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGF
AAYQSAECDYIIAFGGGSPIDTAKAVKILTANPGPSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKE
VIIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEAIRLINLWLPKAVDDGHNLEARE
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIVENFNRPNAVARFARIAQAMGVETRGMSDEAASQ
EAINAIRTLSKRVGIPEGFSKLGVTKEDIEGWLDKALADPCAPCNPRTASRDEVRGLYLEAL
>Mature_381_residues
SFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKLGLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGFA
AYQSAECDYIIAFGGGSPIDTAKAVKILTANPGPSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKEV
IIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEAIRLINLWLPKAVDDGHNLEAREQ
MAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIVENFNRPNAVARFARIAQAMGVETRGMSDEAASQE
AINAIRTLSKRVGIPEGFSKLGVTKEDIEGWLDKALADPCAPCNPRTASRDEVRGLYLEAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=405, Percent_Identity=26.4197530864197, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI48994951, Length=376, Percent_Identity=46.8085106382979, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI1789163, Length=380, Percent_Identity=42.6315789473684, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=40.053050397878, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1787493, Length=407, Percent_Identity=33.1695331695332, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1789386, Length=362, Percent_Identity=27.0718232044199, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17537053, Length=413, Percent_Identity=27.8450363196126, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321181, Length=370, Percent_Identity=42.4324324324324, Blast_Score=296, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24657991, Length=403, Percent_Identity=28.0397022332506, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40297; Mature: 40165

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKLGLLDSLFSALDEHQMS
CCCEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
YHLFDEVFPNPTEELVQKGFAAYQSAECDYIIAFGGGSPIDTAKAVKILTANPGPSTAYS
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHH
GVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKEVIIDPNIIPDIAVDDASVML
CCCCCCCCCCCEEEEECCCCCHHHHCCCEEEEECHHHHHHHHCCCCCCCCCEECCCEEEE
EIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEAIRLINLWLPKAVDDGHNLEARE
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIVENFNRPNAVARFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RIAQAMGVETRGMSDEAASQEAINAIRTLSKRVGIPEGFSKLGVTKEDIEGWLDKALADP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCC
CAPCNPRTASRDEVRGLYLEAL
CCCCCCCCCCHHHHCCEEEECC
>Mature Secondary Structure 
SFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKLGLLDSLFSALDEHQMS
CCEEECCCEEECCCHHHHHHHHHHHCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHH
YHLFDEVFPNPTEELVQKGFAAYQSAECDYIIAFGGGSPIDTAKAVKILTANPGPSTAYS
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHH
GVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKEVIIDPNIIPDIAVDDASVML
CCCCCCCCCCCEEEEECCCCCHHHHCCCEEEEECHHHHHHHHCCCCCCCCCEECCCEEEE
EIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEAIRLINLWLPKAVDDGHNLEARE
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHH
QMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPHGVCNAILLPIVENFNRPNAVARFA
HHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
RIAQAMGVETRGMSDEAASQEAINAIRTLSKRVGIPEGFSKLGVTKEDIEGWLDKALADP
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHCCC
CAPCNPRTASRDEVRGLYLEAL
CCCCCCCCCCHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]