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The map label for this gene is xerC [H]

Identifier: 16767219

GI number: 16767219

Start: 4153787

End: 4154689

Strand: Direct

Name: xerC [H]

Synonym: STM3949

Alternate gene names: 16767219

Gene position: 4153787-4154689 (Clockwise)

Preceding gene: 16767218

Following gene: 16767220

Centisome position: 85.51

GC content: 56.26

Gene sequence:

>903_bases
ATGACGGATGTCGCGCTTTCTCAGGATGTCTCGCGGTTCCTGCGCTATTTAGGCGTGGAGCGCCAGCTTAGCCCCATTAC
CCTGCTGAACTACCAGCGTCAGCTTGATGCCATTATCGCTTTAGCCGGAGAAACCGGGCTGAAAAGCTGGCAACAATGTG
ACGCTGCGATTGTGCGCAGTTTTGCGGTGCGCAGTCGGCGCAAAGGGCTTGGCCCTGCCAGTCTGGCGCTACGTCTCTCG
GCATTGCGAAGCTTTTTTGACTGGTTAGTCAGTCAGGGCGAATTGAAAGCTAACCCGGCAAAGGGTGTCTCCGCACCGAA
AGCGCCGCGTCATCTGCCGAAAAATATTGATGTCGACGACGTTAACCGCCTGCTGGACATCGATCTTAACGATCCGCTCG
CCGTACGTGATCGGGCGATGCTGGAGGTCATGTACGGCGCGGGGCTGCGTTTATCCGAACTGGTTGGCCTGGATATAAAG
CACCTCGATCTCGATACCGGAGAAGTGTGGGTAATGGGTAAAGGCAGCAAAGAGCGACGCCTGCCGATTGGCCGTAACGC
GGTGACGTGGATTGAGCACTGGTTGGATCTGCGCGGCCTGTTCGCCAGCGATGAAGAGGCGTTATTCCTGTCGAAGCTCG
GCAAGCGTATCTCCGCGCGCAATGTCCAAAAACGGTTCGCCGAATGGGGCATAAAGCAGGGGCTAAACAGCCACGTGCAT
CCACATAAGCTGCGCCATTCGTTCGCGACCCATATGCTGGAATCGAGCGGCGATCTGCGCGGCGTGCAAGAGCTGCTGGG
TCATGCCAACCTTTCCACCACCCAAATTTATACTCATCTTGATTTTCAACATCTTGCTTCAGTGTACGACGCGGCGCATC
CGCGCGCTAAACGGGGGAAATAA

Upstream 100 bases:

>100_bases
GCCGTGACCCGCATCACTATCAGCCGGGACAGGGGACGCAGCTTTTACAGGAGATCGCGCTGATGCTGCCGGAACTGCTG
GAACGCTGGATTAAACGCGT

Downstream 100 bases:

>100_bases
TGCGTTTTTACCGGCCTTTGGGGCGTATTGCCGCGCTCACCTTTGACCTGGATGATACCCTTTATGATAACCGTCCGGTG
ATTTTGCGTACTGAGCAGGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTDVALSQDVSRFLRYLGVERQLSPITLLNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLS
ALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Sequences:

>Translated_300_residues
MTDVALSQDVSRFLRYLGVERQLSPITLLNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLS
ALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
>Mature_299_residues
TDVALSQDVSRFLRYLGVERQLSPITLLNYQRQLDAIIALAGETGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLSA
LRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKH
LDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVHP
HKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=300, Percent_Identity=90, Blast_Score=553, Evalue=1e-159,
Organism=Escherichia coli, GI1789261, Length=302, Percent_Identity=37.7483443708609, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1790768, Length=167, Percent_Identity=29.3413173652695, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790767, Length=182, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33600; Mature: 33469

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVALSQDVSRFLRYLGVERQLSPITLLNYQRQLDAIIALAGETGLKSWQQCDAAIVRS
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLDTGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEECCCCCCC
LPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDVALSQDVSRFLRYLGVERQLSPITLLNYQRQLDAIIALAGETGLKSWQQCDAAIVRS
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKGVSAPKAPRHLPKNIDVDD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLDTGEVWVMGKGSKERR
HHHEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCEEEEECCCCCCC
LPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRISARNVQKRFAEWGIKQGLNSHVH
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]