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The map label for this gene is gudP [H]

Identifier: 16767117

GI number: 16767117

Start: 4035356

End: 4036618

Strand: Direct

Name: gudP [H]

Synonym: STM3832

Alternate gene names: 16767117

Gene position: 4035356-4036618 (Clockwise)

Preceding gene: 16767111

Following gene: 16767118

Centisome position: 83.08

GC content: 47.51

Gene sequence:

>1263_bases
ATGTCGATGGCCCTTACCGCCCCCCCAACCAGGAAAAGATTTTTAATCGTTGCCTGTCTGTTTATTGGAATATTTATTGC
TTATCTCGATCGCGTTAATGTTTCGGTATTAGCCGCGAATGAACCCTTCTTAGCCTATATGGGTATTGAAGGCATGCCCT
TGCAAATCGGCATGATGATGACCGTCTTTCTGGCCGCTTATGGTATCGCTAACGTTGTATTATCACCGCTTGGTGATTAT
CTCGGCCCCAGAAAAGCGATGATGCTTTGTATTCTGATCTGGACTATCGCTTTAATGATTGGCGGAGTCGCTACATCATT
CGCTCTAATTATTATTTGCCGTATATTACTGGGCATCGGAGAGGGATTTTATTATCCACTGCAAAGCGTATTTATTAAAA
ACTGGTTCCCGAAGCAGGAACGCGGCAGAGCAAACGCGGCGTGGATCGTCGGCCAGTCAGTCGCTCCCGCCATTGCGATG
CCTTTTTTCACCTGGTGGATAGGCACCCACGGCTGGCGCTCCAACTTCTTTTTATGCGCCGCTCTTGGGTTAATCCCACT
CTGGCTACTTTGGCGATATGTTGCTGATAAACCAGAACAACATAAAAGTATCAGCGAGCAGGAACTGGCTTATATCAAAG
CCGGGCAGGAAACGGAAAGCGCAGGCAGCAGCGAAAGTTTTATGTTGCGGGTCAAACCGGTGATTACCAACTACAGCTAT
TGGCTGCTGGTGCTGTGGTATCTGTGTCTGCAATGTTTATATTGGGGAATGATTACCTGGCTGCCGACCTATCTAAAATC
AGCCAGAGGGTTCAGTTGGGCGGAAATGGGCTGGCTGGCGTCGCTTCCCTTTGTCCTGTCGATATTTGCCAAAGCGGCCG
CAGGCGTCTTCGTCGATAAAATAGGACGCAGCGCCCCCATATTAATGGTATTAATGTTTTTCGCTGGCGTCAGTATCTAT
TTCGGCACCATAACCGAACATAAATATATGTCGGCGGTACTCCTCTCCTTTGCTGTTGCTTTCTGTACGATGGGTACGCC
CGTTGCCTGGACGTTATTACAGGGAATGATACCAGGAAAATCCATATCCGCCGCCAGCGGCGTAATGAACGGCGTCGCCA
ACGGACTCTCTTCATTATCTCCTGTATTTATCGGCTTATTTATTTCTATCACTGGAACTTATACCGGCGGCTTACTATGC
CTGGTTTTTATCAGCGCTATCGCCGTGGTATCGGCATTAATCTTAACGATTAAAAAATATTAA

Upstream 100 bases:

>100_bases
CATCATCACTTAGAGCCTAATGGGATTGGTTCTTAATCAGTAAAAATCAACAAAAACTTATATTTTAAAATAACCTTATC
CGATGAGAAGGAGATCGCTA

Downstream 100 bases:

>100_bases
TTACGAGGAGTAAATGATGAAAATTACCAGCGTTGATATTATTGATGTGGCGAACGATTTTGCGTCCGCCACCAGCAAAT
GGCGTCCGGTGGTGGTAAAA

Product: permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALMIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGSSESFMLRVKPVITNYSY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFAKAAAGVFVDKIGRSAPILMVLMFFAGVSIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSALILTIKKY

Sequences:

>Translated_420_residues
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDY
LGPRKAMMLCILIWTIALMIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGSSESFMLRVKPVITNYSY
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFAKAAAGVFVDKIGRSAPILMVLMFFAGVSIY
FGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLC
LVFISAIAVVSALILTIKKY
>Mature_419_residues
SMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDYL
GPRKAMMLCILIWTIALMIGGVATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMP
FFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGSSESFMLRVKPVITNYSYW
LLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFAKAAAGVFVDKIGRSAPILMVLMFFAGVSIYF
GTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGKSISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCL
VFISAIAVVSALILTIKKY

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=262, Percent_Identity=24.8091603053435, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI6912666, Length=318, Percent_Identity=24.2138364779874, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI9945322, Length=197, Percent_Identity=25.3807106598985, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=26.5116279069767, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI2367379, Length=407, Percent_Identity=26.7813267813268, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87082320, Length=429, Percent_Identity=26.5734265734266, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1789515, Length=413, Percent_Identity=23.2445520581114, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082071, Length=428, Percent_Identity=23.1308411214953, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI2367193, Length=276, Percent_Identity=24.6376811594203, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082404, Length=154, Percent_Identity=26.6233766233766, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790550, Length=260, Percent_Identity=25.3846153846154, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17569727, Length=305, Percent_Identity=26.8852459016393, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86561091, Length=241, Percent_Identity=25.7261410788382, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141318, Length=241, Percent_Identity=25.7261410788382, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=241, Percent_Identity=25.7261410788382, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI25141341, Length=261, Percent_Identity=26.0536398467433, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17561498, Length=210, Percent_Identity=26.1904761904762, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32567120, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534558, Length=210, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561502, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=199, Percent_Identity=25.6281407035176, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=199, Percent_Identity=25.6281407035176, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17552542, Length=346, Percent_Identity=23.121387283237, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17560966, Length=233, Percent_Identity=27.0386266094421, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71991448, Length=256, Percent_Identity=24.609375, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=258, Percent_Identity=25.1937984496124, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=388, Percent_Identity=25.2577319587629, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=267, Percent_Identity=21.3483146067416, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17554148, Length=241, Percent_Identity=24.0663900414938, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115534562, Length=232, Percent_Identity=25.4310344827586, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561500, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=203, Percent_Identity=23.1527093596059, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=203, Percent_Identity=23.1527093596059, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193208223, Length=209, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641682, Length=269, Percent_Identity=25.6505576208178, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24654215, Length=319, Percent_Identity=23.1974921630094, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19922400, Length=304, Percent_Identity=23.3552631578947, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550460, Length=429, Percent_Identity=22.8438228438228, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130167, Length=416, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24580790, Length=269, Percent_Identity=23.4200743494424, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583789, Length=247, Percent_Identity=24.2914979757085, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648416, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356189, Length=304, Percent_Identity=23.0263157894737, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655255, Length=321, Percent_Identity=22.7414330218069, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655271, Length=409, Percent_Identity=21.5158924205379, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20130135, Length=409, Percent_Identity=21.5158924205379, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28573299, Length=402, Percent_Identity=23.134328358209, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46138; Mature: 46007

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMM
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALMIGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGSSESFMLRVKPVITNYSY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFAKAAAGVFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGVSIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSALILTIKKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SMALTAPPTRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFLAYMGIEGMPLQIGMMM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCCHHHHHHH
TVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALMIGGVATSFALIIICRILLGIG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAMPFFTWWIGTHGWRSNFFLCA
CCHHHHHHHHHHHHCCCCHHCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHH
ALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQETESAGSSESFMLRVKPVITNYSY
HHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHCHHH
WLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEMGWLASLPFVLSIFAKAAAGVFVDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGRSAPILMVLMFFAGVSIYFGTITEHKYMSAVLLSFAVAFCTMGTPVAWTLLQGMIPGK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
SISAASGVMNGVANGLSSLSPVFIGLFISITGTYTGGLLCLVFISAIAVVSALILTIKKY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]