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The map label for this gene is gudP [H]

Identifier: 16766983

GI number: 16766983

Start: 3892725

End: 3894035

Strand: Direct

Name: gudP [H]

Synonym: STM3698

Alternate gene names: 16766983

Gene position: 3892725-3894035 (Clockwise)

Preceding gene: 16766982

Following gene: 16766989

Centisome position: 80.14

GC content: 47.83

Gene sequence:

>1311_bases
ATGAACACAATAATAAAGCGCACAAAAGTGCGTCATACCATTCTTATATTTTTATTTCTTGCTACCGTATTTAATTATGC
GGATCGCGCAACTCTATCCGTAGTTGCCCCAATAATGAGTAAAGAATTAGGTTTTGATCCGGAAGCGATGGGCCTGGCCT
TCTCCTCATTTGGTATTGCCTATGTCATTATGCAACTACCCGGCGGTTGGCTATTAGACCGCTACGGTTCACGACTGGTT
TACGGTTGCGCATTGATTGGCTGGTCGTTAGTAACCATGTTTCAGGGAACGATCTATCTGTATGGCAGCCCATTAATTGT
ACTGGTTATTCTACGTCTGCTGATGGGCGCGATTGAAGCGCCTGCCTTTCCGGCGAACAGTCGTTTAAGCGTACAATGGT
TTCCCAATAATGAAAGAGGCTTCGTTACTTCAGTTTATCAGGCTGCGCAATATATCTCGCTGGGCATTATCACCCCGCTA
ATGACGATCATTCTGCATAATTTAAGCTGGCATTTTGTCTTCTATTATATTGGCGCTATTGGCGTGATGCTCGGTATATT
CTGGTTAATGAAAGTCAAAGATCCGATGCACCATCCAAAAGTTAATCAAGCGGAAATTGACTATATTCGTAGCGGTGGTG
GCGAGCCCTCTCTGGGCTGTAAAAAGGAGCCGCAGAAAATAACGTTCGCGCAGATTAAAACCGTCTGTGTTAACCGGATG
ATGATCGGTGTTTATATCGGGCAATTCTGCGTCACCTCTATCACCTGGTTCTTCCTGACCTGGTTCCCGACCTATCTGTA
CCAGGCGAAAGGCATGTCGATTCTGAAAGTCGGTTTTGTGGCCAGTATTCCAGCCATTGCCGGTTTTATTGGCGGCCTGC
TCGGCGGCGTGTTCTCCGACTGGCTACTCAAACGCGGCTATAGCCTTACCGTCGCGCGGAAATTGCCTGTTATCTGCGGT
ATGTTGCTCTCTTGCGTAATTGTGATCGCCAACTACACCTCTTCAGAATTTGTGGTCATTGCGGCGATGAGTCTGGCCTT
TTTTGCCAAAGGGTTTGGTAACCTGGGCTGGTGCGTACTCAGCGACACCTCGCCGAAGGAAGTTCTGGGTATTGCTGGCG
GCGTATTTAACATGTGCGGCAATATGGCAAGCATCGTTACGCCACTGGTCATCGGCGTGATTCTTGCCAATACTCAGTCG
TTCGACTTTGCCATTTTATACGTTGGCTCGATGGGACTTATTGGTCTCATTTCATATCTGTTTATCGTCGGCCCGCTGGA
TCGCATCACGCTGACATCATCCGCAGCCTGA

Upstream 100 bases:

>100_bases
ACATGTGAATTTGGCAAACGCCCTTAACCCGACTGGCGGGAATCCGTCCCGCCTCTCTTACCTTACAGGATGCATTCTGC
CCTTATCTGAGGAGTAGATA

Downstream 100 bases:

>100_bases
TTGTCCACATTGCGAATTCTTCGCTCCGCTGTTCCGGGATTGCACTCCATCGGAACAGCGTTTTTTAGTTGTACCGCGCA
ATTCAGATGCCGTCGCCATA

Product: permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIAYVIMQLPGGWLLDRYGSRLV
YGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEAPAFPANSRLSVQWFPNNERGFVTSVYQAAQYISLGIITPL
MTIILHNLSWHFVFYYIGAIGVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCVNRM
MIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGVFSDWLLKRGYSLTVARKLPVICG
MLLSCVIVIANYTSSEFVVIAAMSLAFFAKGFGNLGWCVLSDTSPKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQS
FDFAILYVGSMGLIGLISYLFIVGPLDRITLTSSAA

Sequences:

>Translated_436_residues
MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIAYVIMQLPGGWLLDRYGSRLV
YGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEAPAFPANSRLSVQWFPNNERGFVTSVYQAAQYISLGIITPL
MTIILHNLSWHFVFYYIGAIGVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCVNRM
MIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGVFSDWLLKRGYSLTVARKLPVICG
MLLSCVIVIANYTSSEFVVIAAMSLAFFAKGFGNLGWCVLSDTSPKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQS
FDFAILYVGSMGLIGLISYLFIVGPLDRITLTSSAA
>Mature_436_residues
MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIAYVIMQLPGGWLLDRYGSRLV
YGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEAPAFPANSRLSVQWFPNNERGFVTSVYQAAQYISLGIITPL
MTIILHNLSWHFVFYYIGAIGVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCVNRM
MIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGVFSDWLLKRGYSLTVARKLPVICG
MLLSCVIVIANYTSSEFVVIAAMSLAFFAKGFGNLGWCVLSDTSPKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQS
FDFAILYVGSMGLIGLISYLFIVGPLDRITLTSSAA

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI21322234, Length=367, Percent_Identity=25.8855585831063, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI9945322, Length=383, Percent_Identity=25.065274151436, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI9966811, Length=379, Percent_Identity=26.1213720316623, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI6912666, Length=380, Percent_Identity=26.5789473684211, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI148743791, Length=404, Percent_Identity=24.2574257425743, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI5031955, Length=274, Percent_Identity=27.7372262773723, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI154350196, Length=418, Percent_Identity=25.3588516746411, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI4885441, Length=389, Percent_Identity=22.879177377892, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI223718438, Length=181, Percent_Identity=28.7292817679558, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI148728191, Length=309, Percent_Identity=25.5663430420712, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI154800443, Length=433, Percent_Identity=23.3256351039261, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI256219598, Length=290, Percent_Identity=23.448275862069, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4503847, Length=290, Percent_Identity=23.448275862069, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI256219483, Length=290, Percent_Identity=23.448275862069, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI256219543, Length=290, Percent_Identity=23.448275862069, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=48.2993197278912, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1789515, Length=442, Percent_Identity=47.5113122171946, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=41.3145539906103, Blast_Score=354, Evalue=5e-99,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=29.7169811320755, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI2367193, Length=418, Percent_Identity=26.555023923445, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1788573, Length=299, Percent_Identity=25.4180602006689, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082071, Length=337, Percent_Identity=22.2551928783383, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533556, Length=415, Percent_Identity=23.1325301204819, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115533554, Length=415, Percent_Identity=23.1325301204819, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17552542, Length=388, Percent_Identity=24.4845360824742, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17535049, Length=419, Percent_Identity=21.2410501193317, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71997452, Length=366, Percent_Identity=23.7704918032787, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17532009, Length=367, Percent_Identity=23.7057220708447, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25151055, Length=240, Percent_Identity=24.1666666666667, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17570335, Length=296, Percent_Identity=23.3108108108108, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=341, Percent_Identity=21.7008797653959, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573299, Length=407, Percent_Identity=26.7813267813268, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583789, Length=397, Percent_Identity=23.9294710327456, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24653727, Length=371, Percent_Identity=26.6846361185984, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI20130167, Length=419, Percent_Identity=24.1050119331742, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24648416, Length=437, Percent_Identity=23.3409610983982, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356189, Length=437, Percent_Identity=23.3409610983982, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573708, Length=432, Percent_Identity=25.6944444444444, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573707, Length=432, Percent_Identity=25.6944444444444, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24584153, Length=382, Percent_Identity=24.3455497382199, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI45550460, Length=421, Percent_Identity=28.7410926365796, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24641682, Length=432, Percent_Identity=24.0740740740741, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24639764, Length=431, Percent_Identity=25.754060324826, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655271, Length=411, Percent_Identity=24.0875912408759, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20130135, Length=411, Percent_Identity=24.0875912408759, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI221474708, Length=296, Percent_Identity=26.0135135135135, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI62484226, Length=356, Percent_Identity=24.7191011235955, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655255, Length=380, Percent_Identity=27.6315789473684, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19922400, Length=372, Percent_Identity=26.3440860215054, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24654215, Length=372, Percent_Identity=26.3440860215054, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19920686, Length=422, Percent_Identity=24.4075829383886, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24658658, Length=433, Percent_Identity=23.094688221709, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129235, Length=379, Percent_Identity=24.5382585751979, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281361682, Length=364, Percent_Identity=24.7252747252747, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47708; Mature: 47708

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YVIMQLPGGWLLDRYGSRLVYGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEA
HHEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCC
PAFPANSRLSVQWFPNNERGFVTSVYQAAQYISLGIITPLMTIILHNLSWHFVFYYIGAI
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
GVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCVNRM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGVFSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
WLLKRGYSLTVARKLPVICGMLLSCVIVIANYTSSEFVVIAAMSLAFFAKGFGNLGWCVL
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
SDTSPKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQSFDFAILYVGSMGLIGLISYL
CCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
FIVGPLDRITLTSSAA
HHHCCCHHEEECCCCC
>Mature Secondary Structure
MNTIIKRTKVRHTILIFLFLATVFNYADRATLSVVAPIMSKELGFDPEAMGLAFSSFGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YVIMQLPGGWLLDRYGSRLVYGCALIGWSLVTMFQGTIYLYGSPLIVLVILRLLMGAIEA
HHEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCC
PAFPANSRLSVQWFPNNERGFVTSVYQAAQYISLGIITPLMTIILHNLSWHFVFYYIGAI
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
GVMLGIFWLMKVKDPMHHPKVNQAEIDYIRSGGGEPSLGCKKEPQKITFAQIKTVCVNRM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
MIGVYIGQFCVTSITWFFLTWFPTYLYQAKGMSILKVGFVASIPAIAGFIGGLLGGVFSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
WLLKRGYSLTVARKLPVICGMLLSCVIVIANYTSSEFVVIAAMSLAFFAKGFGNLGWCVL
HHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEE
SDTSPKEVLGIAGGVFNMCGNMASIVTPLVIGVILANTQSFDFAILYVGSMGLIGLISYL
CCCCHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
FIVGPLDRITLTSSAA
HHHCCCHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]