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The map label for this gene is dcuB [H]

Identifier: 16766885

GI number: 16766885

Start: 3771094

End: 3772413

Strand: Reverse

Name: dcuB [H]

Synonym: STM3599

Alternate gene names: 16766885

Gene position: 3772413-3771094 (Counterclockwise)

Preceding gene: 16766886

Following gene: 16766884

Centisome position: 77.66

GC content: 50.68

Gene sequence:

>1320_bases
ATGTTTTGGACGGAATTATGTTTTATCCTTGTGGCCCTGATGATAGGCGCCAGGATCGGCGGCGTATTTTTAGGGATGGT
CGGCGGGTTAGGCGTCGGCGTGATGGTTTTTATTTTTGGCCTGACGCCTTCTACGCCACCGATTGATGTTATTCTGATTA
TTCTTTCTGTTGTCCTGGCGGCCGCTTCTTTACAGGCCTCCGGCGGGCTGGATTTACTGGTCAAACTGGCGGAAAAAATT
CTGCGTCGCCACCCGCGTTACATTACGTTATTAGCGCCGTTTATCTGTTATATCTTCACTTTTATGTCAGGAACGGGGCA
TGTCGTTTATAGCTTGCTACCGGTTATTTCTGAAGTCGCACGGGATTCAGGTATTCGACCGGAACGTCCTTTATCTATTT
CCGTTATCGCATCGCAACAGGCGATCACCGCCAGTCCTATATCTGCCGCCATGGCGGCGATGATTGGTTTAATGGCGCCG
TTGGGCGTCTCTATTTCAACCATTATGATGATTTGCGTGCCCGCCACGTTAATCGGCGTAGCGATGGGGGCAATAGCGAC
CTTTAATAAAGGAAAAGAGTTAAAAGACGATCCGGAATATCAACGTCGGCTTGCTGAAGGGTTAATTAAACCTGCGCAGA
AAGAAAGTAAAAATACGGTGGTCACTTCGCGCGCCAAATTGTCGGTGGCGTTATTTCTGACCAGTGCGATCGTTATCGTT
CTGTTAGGACTGATTCCGGCGCTGCGGCCCATGGTGGAAACAGCGAAAGGGCTACAACCGCTTTCGATGTCCGCCGCTAT
CCAGATTACGATGCTCTCTTTTGCCTGCCTGATTGTGTTGTTATGCCGACCGCAGGTCGATCAAATTATCAGCGGTACGG
TATTTCGGGCGGGCGCGCTGGCGATTGTCTGCGCCTTCGGCCTGGCCTGGATGAGTGAGACGTTCGTGAATGGTCATATC
GCGTTGATTAAGGCAGAAGTGCAAACTCTATTGCAACAGCATACCTGGCTTATCGCCATTATGATGTTTTTTGTGTCCGC
TATGGTCAGCAGCCAGGCGGCAACGACGTTAATTCTGTTGCCGCTGGGGCTGGCGTTAGGGTTGCCCGCTTATGCATTAA
TCGGCTCCTGGCCTGCCGTTAACGGCTATTTCTTTATTCCGGTGGCGGGGCAGTGTCTGGCGGCGCTGGCGTTTGACGAT
ACCGGTACGACGCGTATTGGCAAATATGTGCTTAACCATAGTTTTATGCGTCCGGGATTAGTTAACGTGATTGTCTCGGT
CATTGTCGGGCTGTTAATAGGAAAAATGGTTCTGGCCTGA

Upstream 100 bases:

>100_bases
TATCTCATTACGGCGCATTTGGTTTTGGTAAACCGTTTGCACAATAGGTTACGTCCCTCAATGTAAAGCGACACTCACTC
CAGATAACCCAGGAGGAAGT

Downstream 100 bases:

>100_bases
TTGTTATTCATGTTTTTATAGCACACGCCACTTATTATTTTTAATTCAGAGGAAGAAAATGAAAATTAGAGTTTTCATGG
CCACCGTGTTGCTGCTCATC

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLAAASLQASGGLDLLVKLAEKI
LRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVARDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAP
LGVSISTIMMICVPATLIGVAMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVIV
LLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGALAIVCAFGLAWMSETFVNGHI
ALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLILLPLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDD
TGTTRIGKYVLNHSFMRPGLVNVIVSVIVGLLIGKMVLA

Sequences:

>Translated_439_residues
MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLAAASLQASGGLDLLVKLAEKI
LRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVARDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAP
LGVSISTIMMICVPATLIGVAMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVIV
LLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGALAIVCAFGLAWMSETFVNGHI
ALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLILLPLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDD
TGTTRIGKYVLNHSFMRPGLVNVIVSVIVGLLIGKMVLA
>Mature_439_residues
MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLAAASLQASGGLDLLVKLAEKI
LRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVARDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAP
LGVSISTIMMICVPATLIGVAMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVIV
LLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGALAIVCAFGLAWMSETFVNGHI
ALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLILLPLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDD
TGTTRIGKYVLNHSFMRPGLVNVIVSVIVGLLIGKMVLA

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=445, Percent_Identity=41.3483146067416, Blast_Score=312, Evalue=3e-86,
Organism=Escherichia coli, GI1790565, Length=414, Percent_Identity=38.8888888888889, Blast_Score=281, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46510; Mature: 46510

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AASLQASGGLDLLVKLAEKILRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVA
HHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAPLGVSISTIMMICVPATLIGV
HCCCCCCCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVIV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
LLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
AIVCAFGLAWMSETFVNGHIALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLILL
HHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDDTGTTRIGKYVLNHSFMRPGL
HHHHHHCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCH
VNVIVSVIVGLLIGKMVLA
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFWTELCFILVALMIGARIGGVFLGMVGGLGVGVMVFIFGLTPSTPPIDVILIILSVVLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AASLQASGGLDLLVKLAEKILRRHPRYITLLAPFICYIFTFMSGTGHVVYSLLPVISEVA
HHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RDSGIRPERPLSISVIASQQAITASPISAAMAAMIGLMAPLGVSISTIMMICVPATLIGV
HCCCCCCCCCCEEEEEECCCHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AMGAIATFNKGKELKDDPEYQRRLAEGLIKPAQKESKNTVVTSRAKLSVALFLTSAIVIV
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHH
LLGLIPALRPMVETAKGLQPLSMSAAIQITMLSFACLIVLLCRPQVDQIISGTVFRAGAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHH
AIVCAFGLAWMSETFVNGHIALIKAEVQTLLQQHTWLIAIMMFFVSAMVSSQAATTLILL
HHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLGLALGLPAYALIGSWPAVNGYFFIPVAGQCLAALAFDDTGTTRIGKYVLNHSFMRPGL
HHHHHHCCHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCH
VNVIVSVIVGLLIGKMVLA
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]