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The map label for this gene is argD [H]

Identifier: 16766756

GI number: 16766756

Start: 3618456

End: 3619673

Strand: Reverse

Name: argD [H]

Synonym: STM3468

Alternate gene names: 16766756

Gene position: 3619673-3618456 (Counterclockwise)

Preceding gene: 16766757

Following gene: 16766753

Centisome position: 74.52

GC content: 55.91

Gene sequence:

>1218_bases
ATGGCAACTGAACAAACGGCTATTACGCGCGCAACTTTTGATGAGGTGATTCTGCCTGTTTATGCACCGGCGGACTTTAT
TCCGGTCAAAGGTAAAGGCAGCCGAGTATGGGATCAGCAGGGCAAAGAGTATATTGATTTCGCCGGCGGGATTGCAGTGA
CTGCGCTGGGCCATTGCCATCCGGCGCTGGTCGAGGCGCTGAAATCCCAGGGGGAAACCTTGTGGCATACCAGTAACGTT
TTTACCAATGAACCAGCGTTGCGTCTGGGACGTAAACTGATCGACGCCACGTTTGCCGAGCGCGTGCTGTTTATGAATTC
CGGCACCGAAGCGAACGAAACCGCTTTTAAACTGGCGCGTCATTATGCCTGCGTGCGCCATAGCCCGTTCAAAACGAAAA
TCATTGCCTTCCATAACGCTTTTCATGGCCGTTCCTTGTTTACCGTCTCTGTAGGCGGGCAGCCGAAATATTCCGACGGC
TTTGGGCCGAAACCCGCCGATATTATTCACGTTCCCTTCAACGATCTTCATGCGGTGAAAGCGGTAATGGATGACCACAC
CTGCGCGGTGGTGGTCGAGCCGATTCAGGGTGAAGGCGGCGTGCAGGCGGCTACACCGGAATTCCTCAAAGGGTTACGCG
ACCTGTGTGACGAGCATCAGGCGTTGCTGGTGTTTGATGAAGTGCAGTGTGGGATGGGGCGCACCGGAGACCTGTTTGCC
TATATGCACTACGGCGTCACGCCGGATATCCTCACCAGCGCCAAAGCGTTAGGCGGCGGTTTTCCGGTGAGCGCCATGCT
GACCACGCAGGAAATAGCCTCGGCCTTCCATGTAGGTTCGCATGGTTCAACCTATGGCGGCAATCCGCTGGCCTGTGCGG
TGGCTGGCGCGGCATTCGATATTATTAATACGCCAGAGGTACTACAAGGCATTCACACTAAGCGGCAACAGTTTGTGCAA
CATTTGCAGGCGATTGACGAGCAATTTGACATTTTCAGCGATATTCGCGGCATGGGGCTGCTGATTGGCGCGGAACTGAA
GCCGAAGTACAAAGGTCGGGCGCGCGATTTTCTGTACGCAGGCGCGGAGGCCGGCGTGATGGTGCTCAATGCCGGAGCCG
ACGTGATGCGTTTTGCCCCGTCGCTGGTGGTGGAAGAGGCGGATATCCATGAAGGAATGCAGCGCTTTGCGCAGGCGGTA
GGGAAGGTGGTGGCCTGA

Upstream 100 bases:

>100_bases
TTCCTCCGGCGTTGATTTGTGGTTGCTATTGAGTGATTTTTTATTCATATTTTGTGATTATAATTTCACTGGCATTTCTA
CTTAACCGGGTGGTAATGAT

Downstream 100 bases:

>100_bases
TGGCGGATTGCCGGATAAGCGTAGCGCATCCGGCGGTCGGTCTTAACCTTTTGTATCCCGTAGCCGCTTACTCAGCCAGA
TACCGTGATGCGGACGCTGA

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNV
FTNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQ
HLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAV
GKVVA

Sequences:

>Translated_405_residues
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNV
FTNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQ
HLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAV
GKVVA
>Mature_404_residues
ATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVF
TNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGF
GPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFAY
MHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQH
LQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAVG
KVVA

Specific function: Involved in both the arginine and lysine biosynthetic pathways [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=36.1979166666667, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=36.6666666666667, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=28.8416075650118, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI37574042, Length=401, Percent_Identity=30.1745635910224, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI226442709, Length=374, Percent_Identity=30.7486631016043, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=394, Percent_Identity=28.1725888324873, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI226442705, Length=401, Percent_Identity=28.927680798005, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=430, Percent_Identity=22.7906976744186, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI38679950, Length=430, Percent_Identity=22.7906976744186, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI38679946, Length=430, Percent_Identity=22.7906976744186, Blast_Score=85, Evalue=9e-17,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=91.8316831683168, Blast_Score=779, Evalue=0.0,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=61.3065326633166, Blast_Score=519, Evalue=1e-148,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=35.8910891089109, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1787560, Length=403, Percent_Identity=33.0024813895782, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI145693181, Length=393, Percent_Identity=34.0966921119593, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786991, Length=414, Percent_Identity=30.9178743961353, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786349, Length=311, Percent_Identity=32.1543408360129, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=375, Percent_Identity=37.8666666666667, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=28.4722222222222, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=37.546468401487, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.9044289044289, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=418, Percent_Identity=25.1196172248804, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=34.1463414634146, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=38.5964912280702, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.2431761786601, Blast_Score=224, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=334, Percent_Identity=28.7425149700599, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=451, Percent_Identity=25.2771618625277, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=35.978835978836, Blast_Score=228, Evalue=8e-60,
Organism=Drosophila melanogaster, GI28574759, Length=421, Percent_Identity=28.7410926365796, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI161085790, Length=416, Percent_Identity=28.6057692307692, Blast_Score=175, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356575, Length=360, Percent_Identity=30.8333333333333, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI281366494, Length=434, Percent_Identity=22.8110599078341, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24667139, Length=434, Percent_Identity=22.8110599078341, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24667143, Length=434, Percent_Identity=22.8110599078341, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11; =2.6.1.17 [H]

Molecular weight: Translated: 43670; Mature: 43539

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCCHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHCCC
PALVEALKSQGETLWHTSNVFTNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAVGKVVA
CCCCCEEEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEYIDFAGGIAVTALGHCH
CCCHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHCCC
PALVEALKSQGETLWHTSNVFTNEPALRLGRKLIDATFAERVLFMNSGTEANETAFKLAR
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
HYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVK
HHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCEEECCCHHHHHHH
AVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDEHQALLVFDEVQCGMGRTGDLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCEEE
YMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAFHVGSHGSTYGGNPLACAVAGAAFD
EEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHC
IINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSDIRGMGLLIGAELKPKYKGRARDFLYA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHEEE
GAEAGVMVLNAGADVMRFAPSLVVEEADIHEGMQRFAQAVGKVVA
CCCCCEEEEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]