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The map label for this gene is sun [H]

Identifier: 16766697

GI number: 16766697

Start: 3578460

End: 3579749

Strand: Direct

Name: sun [H]

Synonym: STM3408

Alternate gene names: 16766697

Gene position: 3578460-3579749 (Clockwise)

Preceding gene: 16766696

Following gene: 16766698

Centisome position: 73.67

GC content: 53.64

Gene sequence:

>1290_bases
ATGAAAAAACAAAACAATTTACGTAGTCTGGCAGCACAGGCCGTTGAACAGGTCGTCGAGCAGGGACAATCATTAAGTAA
TGTGCTCCCGCCGCTGCAACAAAAAGTCGCCGATAAAGACAAAGCGCTACTTCAGGAGCTGTGCTTTGGCGTACTGCGCA
CCCTTTCACAGCTGGAATGGCTGATCAATAAGCTGATGTCTCGTCCAATGACCGGCAAGCAGCGTACAGTGCATTACTTA
ATTATGGTCGGCTTTTATCAGTTGCTGTACACCCGCGTTCCTCCCCATGCGGCGCTGGCTGAAACCGTTGAAGGCGCGGT
CTCCATCAAACGTCCGCAGTTGAAAGGGTTAATTAACGGCGTCCTGCGCCAGTTCCAGCGCCAGCAGGAAACGTTGCTTA
ATGAGTTTGCGACCAGCGATGCGCGCTTTTTACATCCAGGTTGGCTGGTAAAGCGTTTGCAAAATGCTTACCCCACACAG
TGGCAACACATTATTGAAGCGAATAACCAGCGTCCACCGATGTGGCTACGTGTAAATCGTACACACCACACCCGCGACGG
TTGGCTTGGCTTACTTGAAGACGCAGGCATGAAGGGATATCCCCATCCCGATTATCCCGACGCTGTACGTCTGGAAACGC
CAGCTCCGGTACATGCTTTACCCGGTTTTGCTGAGGGTTGGGTAACTGTCCAGGATGCCTCTGCGCAGGGATGTGCGGTT
TTTCTCGCTCCTCAGAACGGTGAGCACATTTTAGACTTGTGCGCCGCGCCCGGCGGTAAAACCACGCATATTCTCGAAGT
GGCCCCCGAAGCAGACGTGTTGGCAGTTGATATTGATGAACAACGACTCTCCCGCGTTTACGACAACCTAAAGCGTCTTG
GGATGAAAGCGACAGTTAAACAAGGGGATGGACGTTATCCCTCCCAATGGTGCGGCGAGCAGCAGTTTGACCGTATTCTG
CTGGATGCGCCCTGCTCCGCAACCGGCGTCATTCGCCGTCATCCAGATATCAAATGGCTGCGTCGCGATCGCGATATCGC
GGAACTGGCGCAATTACAGGCGGAAATTCTTGATGCCGTCTGGCCGCGCCTGAAGCCCGGCGGGACGCTGGTTTACGCCA
CCTGTTCCGTACTGCCGGAAGAAAACCGCGATCAGATCAAAACCTTTTTACAACGCACTCCCGATGCCGCGCTCAGCGAA
ACGGGAACACCTGATCAGCCAGGACAACAGAATCTGCCGGGCGGCGAAGAAGGTGATGGGTTCTTTTACGCTAAGCTAAT
CAAGAAGTGA

Upstream 100 bases:

>100_bases
GTTAAATTCACGCCGGGAATGGTTTATTCCTGGTAACCGTCTTGCCTGACGGTCACGTCTTTATAAGCCCGGTGTTACCG
GGCATTTTTATTTTATACAT

Downstream 100 bases:

>100_bases
TGAGATAACGGGCCACGACTGATGAAAATTATCATACTGGGCGCAGGGCAAGTTGGCGGAACACTGGCGGAAAACCTGGT
CGGCGAAAACAACGACATCA

Product: 16S rRNA methyltransferase B

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYL
IMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQ
WQHIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAV
FLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRIL
LDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSE
TGTPDQPGQQNLPGGEEGDGFFYAKLIKK

Sequences:

>Translated_429_residues
MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYL
IMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQ
WQHIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAV
FLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRIL
LDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSE
TGTPDQPGQQNLPGGEEGDGFFYAKLIKK
>Mature_429_residues
MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYL
IMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQ
WQHIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAV
FLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRIL
LDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSE
TGTPDQPGQQNLPGGEEGDGFFYAKLIKK

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=282, Percent_Identity=36.5248226950355, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI76150623, Length=282, Percent_Identity=36.5248226950355, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI32698918, Length=198, Percent_Identity=32.8282828282828, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI270288816, Length=249, Percent_Identity=29.3172690763052, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI23199998, Length=249, Percent_Identity=29.3172690763052, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI8922322, Length=249, Percent_Identity=29.3172690763052, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI270288818, Length=249, Percent_Identity=29.3172690763052, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI11545785, Length=289, Percent_Identity=26.643598615917, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI301336155, Length=207, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI39995082, Length=207, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40316918, Length=162, Percent_Identity=32.0987654320988, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367212, Length=429, Percent_Identity=88.3449883449883, Blast_Score=798, Evalue=0.0,
Organism=Escherichia coli, GI87081985, Length=222, Percent_Identity=32.8828828828829, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536757, Length=261, Percent_Identity=32.5670498084291, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25143471, Length=285, Percent_Identity=29.4736842105263, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=270, Percent_Identity=33.7037037037037, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319447, Length=191, Percent_Identity=30.3664921465969, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI22024126, Length=250, Percent_Identity=33.6, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920494, Length=175, Percent_Identity=31.4285714285714, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24668781, Length=234, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356513, Length=226, Percent_Identity=31.4159292035398, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355201, Length=207, Percent_Identity=30.9178743961353, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: =2.1.1.176 [H]

Molecular weight: Translated: 48112; Mature: 48112

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEW
CCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLING
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQHIIEANNQRPPMWLRVNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECC
THHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAV
CCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCEEEEECCCCCCCEE
FLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVK
EEECCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCHHEEC
QGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAV
CCCCCCCHHHCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHH
WPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDG
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC
FFYAKLIKK
EEHHHHHCC
>Mature Secondary Structure
MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEW
CCCCHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLING
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
VLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQHIIEANNQRPPMWLRVNR
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEECC
THHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAV
CCCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHCCCCCCCEEEEECCCCCCCEE
FLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVK
EEECCCCCHHHHHHCCCCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCHHEEC
QGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAV
CCCCCCCHHHCCHHHHHHHHHCCCCCCCCHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHH
WPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDG
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCC
FFYAKLIKK
EEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA