| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
Click here to switch to the map view.
The map label for this gene is pnp [H]
Identifier: 16766580
GI number: 16766580
Start: 3449247
End: 3451382
Strand: Reverse
Name: pnp [H]
Synonym: STM3282
Alternate gene names: 16766580
Gene position: 3451382-3449247 (Counterclockwise)
Preceding gene: 16766581
Following gene: 16766579
Centisome position: 71.05
GC content: 56.27
Gene sequence:
>2136_bases TTGCTTAATCCGATCGTTCGTAAATTCCAGTACGGTCAGCATACCGTTACGCTGGAAACTGGCATGATGGCGCGTCAGGC CACTGCCGCTGTTATGGTAAGCATGGATGACACCGCCGTATTCGTTACCGTTGTCGGCCAGAAAAAAGCCAAGCCAGGCC AGGACTTCTTCCCACTGACCGTTAACTATCAGGAGCGTACCTACGCTGCTGGTCGTATCCCGGGCAGCTTCTTCCGTCGT GAAGGCCGTCCAAGCGAAGGCGAAACCCTGATCGCGCGTCTGATTGACCGCCCGGTTCGTCCGCTGTTCCCGGAAGGCTT CGTTAACGAAGTGCAGGTTATCGCGACCGTCGTTTCCGTTAACCCGCAGGTTAACCCGGATATCGTGGCGATGATCGGCG CATCCGCTGCGCTGTCGCTGTCCGGCATTCCGTTCAACGGCCCAATCGGCGCGGCGCGCGTAGGTTACATCAATGACCAG TACGTGCTGAACCCGACCCAGGACGAGCTGAAAGAAAGCAAGCTGGACCTGGTGGTTGCCGGTACCGAAGCGGCTGTGCT GATGGTGGAATCCGAAGCTGAACTGCTGAGCGAAGACACTATGCTGGGCGCGGTGGTATTCGGTCACGAGCAGCAGCAGG TTGTTATCCAGGCGATCAACGATCTGGTGAAAGAAGCCGGTAAACCGCGTTGGGACTGGCAGCCGGAAGCCGTCAACGAC GCGTTGAACGCGCGTGTTGCTGCGCTGGCTGAATCTCGTCTGAGCGACGCGTACCGCATCACCGATAAACAAGAGCGCTA TGCTCAGGTTGACGTAATCAAATCCGAAACCATCGAGCAGCTTATTGCAGAAGATGAAACTCTGGATGCTAACGAGCTGG GCGAAATCCTGCACGCTATCGAGAAAAACGTGGTGCGTAGCCGCGTACTGGCAGGCGAGCCGCGTATTGATGGCCGTGAA AAAGACATGATCCGTGGTCTGGACGTGCGCACTGGCGTACTGCCGCGTACTCACGGTTCCGCTCTGTTTACCCGTGGTGA AACGCAGGCGCTGGTTACCGCAACTCTGGGTACTGCCCGTGACGCGCAGGTGCTTGATGAACTGATGGGCGAGCGTACTG ACAGCTTCCTGTTCCACTACAACTTCCCTCCGTACTCCGTAGGCGAAACCGGCATGGTCGGTTCTCCGAAGCGTCGTGAA ATTGGTCACGGTCGTCTGGCGAAGCGCGGCGTGCTGGCAGTGATGCCGGACATGGATAAATTCCCGTACACCGTTCGCGT GGTGTCTGAAATCACCGAATCCAACGGTTCTTCTTCTATGGCTTCCGTGTGCGGCGCTTCTCTGGCGCTGATGGACGCTG GCGTGCCAATTAAAGCCGCCGTAGCAGGTATCGCTATGGGTCTGGTGAAAGAAGGCGACAACTACGTTGTACTGTCTGAC ATTCTGGGCGACGAAGATCACCTGGGCGATATGGACTTCAAAGTGGCGGGTTCCCGCGACGGTATCTCTGCGCTGCAGAT GGATATCAAAATTGAAGGTATCACCAAAGAGATCATGCAGGTTGCGTTGAACCAGGCTAAAGGTGCGCGTCTGCACATCC TGGGCGTGATGGAACAGGCGATCAACGCGCCGCGCGGCGATATCTCTGAATTTGCGCCGCGTATCCATACCATCAAGATC AGCACGGACAAGATCAAAGACGTGATCGGTAAAGGCGGTTCTGTGATCCGCGCGCTGACTGAAGAGACCGGCACCACCAT CGAAATCGAAGATGACGGTACTGTGAAGATCGCGGCGACCGACGGTGAAAAAGCGAAATACGCTATCCGTCGTATCGAAG AGATCACCGCAGAGATCGAAGTCGGCCGTATCTACAATGGTAAAGTGACCCGTATCGTTGACTTTGGCGCGTTTGTTGCC ATCGGCGGCGGGAAAGAAGGTCTGGTTCACATCTCTCAAATCGCGGATAAACGTGTAGAGAAAGTGACCGACTATCTGCA GATGGGTCAGGAAGTCCCGGTTAAGGTTCTGGAAGTTGACCGCCAGGGCCGTGTACGTCTGAGCATTAAAGAAGCAACCG AGCAGTCTCAACCTGCGGCTGCGCCGGAAGCTCCGGCGAGCGAACAGGCCGAGTAA
Upstream 100 bases:
>100_bases ATATCAGGGTTAGGGTTGTCATTAGTCGCGAGGATGCGCAGAAGATCGGGTATTAACGACGGCGCGTATTATGCCGTCAA AAATTGGAAAGGATATTATT
Downstream 100 bases:
>100_bases GGTAGCCTTTTGCCCTCCGCAGTGCGGAGGGCTTTAGACCTGGCTGGACGCCTTGTTGAGCCACCGGGGAACAGGACGTT CATTCAATCGTTGTCTTCGG
Product: polynucleotide phosphorylase/polyadenylase
Products: NA
Alternate protein names: Polynucleotide phosphorylase; PNPase [H]
Number of amino acids: Translated: 711; Mature: 711
Protein sequence:
>711_residues MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRR EGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVND ALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGRE KDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRRE IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKI STDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVA IGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE
Sequences:
>Translated_711_residues MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRR EGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVND ALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGRE KDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRRE IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKI STDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVA IGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE >Mature_711_residues MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRR EGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVND ALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGRE KDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRRE IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKI STDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVA IGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE
Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction [H]
COG id: COG1185
COG function: function code J; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 S1 motif domain [H]
Homologues:
Organism=Homo sapiens, GI188528628, Length=707, Percent_Identity=39.8868458274399, Blast_Score=456, Evalue=1e-128, Organism=Escherichia coli, GI145693187, Length=697, Percent_Identity=97.2740315638451, Blast_Score=1376, Evalue=0.0, Organism=Caenorhabditis elegans, GI115534063, Length=713, Percent_Identity=32.9593267882188, Blast_Score=343, Evalue=2e-94, Organism=Caenorhabditis elegans, GI17535281, Length=80, Percent_Identity=46.25, Blast_Score=72, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6320850, Length=107, Percent_Identity=32.7102803738318, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI281362905, Length=708, Percent_Identity=37.8531073446328, Blast_Score=457, Evalue=1e-128, Organism=Drosophila melanogaster, GI24651641, Length=708, Percent_Identity=37.8531073446328, Blast_Score=457, Evalue=1e-128, Organism=Drosophila melanogaster, GI24651643, Length=708, Percent_Identity=37.8531073446328, Blast_Score=457, Evalue=1e-128, Organism=Drosophila melanogaster, GI161079377, Length=654, Percent_Identity=37.4617737003058, Blast_Score=416, Evalue=1e-116,
Paralogues:
None
Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001247 - InterPro: IPR015847 - InterPro: IPR004087 - InterPro: IPR009019 - InterPro: IPR004088 - InterPro: IPR018111 - InterPro: IPR012340 - InterPro: IPR016027 - InterPro: IPR012162 - InterPro: IPR015848 - InterPro: IPR003029 - InterPro: IPR020568 - InterPro: IPR022967 [H]
Pfam domain/function: PF00013 KH_1; PF03726 PNPase; PF01138 RNase_PH; PF03725 RNase_PH_C; PF00575 S1 [H]
EC number: =2.7.7.8 [H]
Molecular weight: Translated: 77040; Mature: 77040
Theoretical pI: Translated: 4.79; Mature: 4.79
Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLT CCCHHHHHHHCCCEEEEEECCCHHHHCEEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE VNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSV EECCHHEEECCCCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEC NPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVA CCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCEEECCCHHHHHHCCCCEEEE GTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVND CCCEEEEEEECHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH ALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAI HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH EKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTAR HHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCC DAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDK HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCCCCCHHHCCEEEECCCCCC FPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD CCCHHHHHHHHHHCCCCHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHCCCCCEEEEEH ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQA HCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHH INAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAAT HCCCCCCHHHHCCCEEEEEECHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEEEC DGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVE CCCHHHHHHHHHHHHHHHEEEEEEECCEEEEEEECCEEEEECCCCCCCEEHHHHHHHHHH KVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE HHHHHHHCCCCCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLT CCCHHHHHHHCCCEEEEEECCCHHHHCEEEEEEEECCCEEEEEEECCCCCCCCCCCEEEE VNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPLFPEGFVNEVQVIATVVSV EECCHHEEECCCCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEEC NPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVA CCCCCCCEEEEECCCCEEEECCCCCCCCCCCEEEEEECCCEEECCCHHHHHHCCCCEEEE GTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQAINDLVKEAGKPRWDWQPEAVND CCCEEEEEEECHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH ALNARVAALAESRLSDAYRITDKQERYAQVDVIKSETIEQLIAEDETLDANELGEILHAI HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH EKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTAR HHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCC DAQVLDELMGERTDSFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLAVMPDMDK HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHCCCCCCHHHCCEEEECCCCCC FPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD CCCHHHHHHHHHHCCCCHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHCCCCCEEEEEH ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQA HCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCEEEEHHHHHHH INAPRGDISEFAPRIHTIKISTDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAAT HCCCCCCHHHHCCCEEEEEECHHHHHHHHCCCCHHHHHHHHCCCCEEEECCCCEEEEEEC DGEKAKYAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVE CCCHHHHHHHHHHHHHHHEEEEEEECCEEEEEEECCEEEEECCCCCCCEEHHHHHHHHHH KVTDYLQMGQEVPVKVLEVDRQGRVRLSIKEATEQSQPAAAPEAPASEQAE HHHHHHHCCCCCCEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA