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The map label for this gene is fadH [H]

Identifier: 16766518

GI number: 16766518

Start: 3386255

End: 3388273

Strand: Direct

Name: fadH [H]

Synonym: STM3219

Alternate gene names: 16766518

Gene position: 3386255-3388273 (Clockwise)

Preceding gene: 161353584

Following gene: 16766520

Centisome position: 69.71

GC content: 58.69

Gene sequence:

>2019_bases
ATGAGCTACCCGTCGCTGTTCGCCCCGCTCGATCTGGGCTTTACTACTCTCAGAAACCGTGTGCTGATGGGATCGATGCA
CACGGGTCTGGAGGAACATCCTGATGGCGCTGAGCGCCTGGCGGCATTTTATGCCGAGCGCGCGCGACACGGCGTAGCGT
TAATCGTCACCGGCGGTATTGCGCCCGTTCCCTCCGGGGTCGTGATGACCGGCGGCGCGATGCTGAACGATGCCAGCCAG
TTAACGCCTCACCGCGTGGTGACCGATGCCGTACATGCGCAAGGCGGTAAAATCGCGCTGCAAATTCTGCACACCGGGCG
TTACAGCTATCAGCCGCACCTGGTCGCGCCGTCGGCAATTCAGGCGCCAATCAACCGCTTTATGCCGCATGAACTGACGC
ATGATGAAATCTTGCAGTTAATCGACGACTTCGCGCATTGCGCGCAACTGGCGCGGGAAGCAGGCTACGACGGCGTAGAG
GTGATGGGATCAGAGGGCTATCTGATTAATGAATTTCTCACGCGGCGAACTAACCATCGCGATGACGAATGGGGCGGCGA
CTATGCCAGCCGTATGCGCTTCGCGGTTGAGGTAGTACGCGCGGTACGCCAGCGGGTAGGGAACGACTTTATTATTATCT
ATCGCCTGTCGATGCTCGATCTGGTGGAAAATGGCGGCACGTTCGACGAAACGGTACAACTGGCGCAAGCCATTGAAGCC
GCAGGCGCAAGCCTAATTAATACCGGCATTGGCTGGCATGAGGCGCGAATCCCGACCATCGCCACGCCAGTACCGCGTGG
CGCCTTTAGCTGGGTGACGCGGAAACTCAAAGGTCATGTGTCGGTTCCGCTGATCGCGACCAATCGCATTAACGATCCGC
AGGTCGCCGAGACGATCCTGACGCGCGGCGATGCCGATATGGTGTCGATGGCGCGTCCCTTCCTTGCCGATGCCGAATTC
CTGACTAAAGCGCAATCCGGACGCGCAGATGAGATCAACACCTGTATCGGCTGTAATCAGGCCTGTCTGGATCGGATCTT
CATCGGCAAAGTGACCTCCTGTCTGGTGAACCCGCGCGCCTGTCACGAAACCCACATGCCGATAACGCCGGCCATACGCA
AAAAGAACCTGGCCGTTGTCGGCGCAGGCCCGGCGGGGCTGGCTTTCGCGATTAACGCCGCGTCGCGCGGCCATCATGTC
ACGCTGTTTGACGCTCAGAGTGAAATTGGCGGTCAGTTTACTATCGCCAGGCAGATCCCGGGTAAAGAGGAGTTTTACGA
AACGCTGCGCTACTACCGTCGAATGATCGATGTTACTGGCGTTACGCTGAAACTGAACCAACGGGTGAACGCAGAGGATC
TTCAGCCGTTTGACGAAGCGATCCTCGCTTGTGGAATAGTACCGCGCCGCCCGCCGATAGACGGTATCGATCATCCAAAA
GCATTGACCTACCTGGAGGTATTGCGCGATAAGGCGCCGGTTGGTAAGCGAGTGGCGATCATCGGCTGCGGCGGGATCGG
TTTTGACACGGCCATGTATCTGAGCCAGCACGGCGAATCCACCAGCCAAAATATTGCTGAATTTTGTACGGAATGGGGAA
TTGATACCAGCCTGCAACAGGCAGGCGGTCTGCGCCCGGAAGGCCCGCGCCTGGCACGTAGTCCACGGCAAATCGTCATG
CTGCAACGCAAAACCAGCAAGCCGGGCGAAGGGTTAGGTAAAACCACCGGCTGGATCCATCGCGCGACGTTACTGGCGCG
CGGCGTGAAGATGATCCCGGCGGTCAGTTACCAGAAGATCGACGACGACGGATTACATCTCTTGATCGGCGGCGAACCGC
AGTTGCTGGAAGTGGATCATGTGGTGATCTGCGCCGGACAGGAACCTCGCCGCGAGCTGGCGGACCCGTTACGCGCCGCA
GGTAAAACGGTACATCTTATCGGCGGATGCGATGTCGCGATGGAGCTGGATGCCCGACGGGCGATTGCCCAGGGCACCCG
ACTGGCACTGGAGATTTAA

Upstream 100 bases:

>100_bases
ATCACAATCACCACATTCCCCTTTTCCCTTTTACCTCGCGACGGCTACAGTAGTAACTCATCCGACCACATAACAATAAT
TTTACATACTGGATACGCTT

Downstream 100 bases:

>100_bases
CGACTTTGCCTGATGGCGCTACGCTTATCGGGCTTACGCCGTCATACCGGTTTTATAGGCCGGTATGACGCTTGAGCGCC
TTATCGACGGCGTCCCTGCT

Product: 2,4-dieonyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MSYPSLFAPLDLGFTTLRNRVLMGSMHTGLEEHPDGAERLAAFYAERARHGVALIVTGGIAPVPSGVVMTGGAMLNDASQ
LTPHRVVTDAVHAQGGKIALQILHTGRYSYQPHLVAPSAIQAPINRFMPHELTHDEILQLIDDFAHCAQLAREAGYDGVE
VMGSEGYLINEFLTRRTNHRDDEWGGDYASRMRFAVEVVRAVRQRVGNDFIIIYRLSMLDLVENGGTFDETVQLAQAIEA
AGASLINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSVPLIATNRINDPQVAETILTRGDADMVSMARPFLADAEF
LTKAQSGRADEINTCIGCNQACLDRIFIGKVTSCLVNPRACHETHMPITPAIRKKNLAVVGAGPAGLAFAINAASRGHHV
TLFDAQSEIGGQFTIARQIPGKEEFYETLRYYRRMIDVTGVTLKLNQRVNAEDLQPFDEAILACGIVPRRPPIDGIDHPK
ALTYLEVLRDKAPVGKRVAIIGCGGIGFDTAMYLSQHGESTSQNIAEFCTEWGIDTSLQQAGGLRPEGPRLARSPRQIVM
LQRKTSKPGEGLGKTTGWIHRATLLARGVKMIPAVSYQKIDDDGLHLLIGGEPQLLEVDHVVICAGQEPRRELADPLRAA
GKTVHLIGGCDVAMELDARRAIAQGTRLALEI

Sequences:

>Translated_672_residues
MSYPSLFAPLDLGFTTLRNRVLMGSMHTGLEEHPDGAERLAAFYAERARHGVALIVTGGIAPVPSGVVMTGGAMLNDASQ
LTPHRVVTDAVHAQGGKIALQILHTGRYSYQPHLVAPSAIQAPINRFMPHELTHDEILQLIDDFAHCAQLAREAGYDGVE
VMGSEGYLINEFLTRRTNHRDDEWGGDYASRMRFAVEVVRAVRQRVGNDFIIIYRLSMLDLVENGGTFDETVQLAQAIEA
AGASLINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSVPLIATNRINDPQVAETILTRGDADMVSMARPFLADAEF
LTKAQSGRADEINTCIGCNQACLDRIFIGKVTSCLVNPRACHETHMPITPAIRKKNLAVVGAGPAGLAFAINAASRGHHV
TLFDAQSEIGGQFTIARQIPGKEEFYETLRYYRRMIDVTGVTLKLNQRVNAEDLQPFDEAILACGIVPRRPPIDGIDHPK
ALTYLEVLRDKAPVGKRVAIIGCGGIGFDTAMYLSQHGESTSQNIAEFCTEWGIDTSLQQAGGLRPEGPRLARSPRQIVM
LQRKTSKPGEGLGKTTGWIHRATLLARGVKMIPAVSYQKIDDDGLHLLIGGEPQLLEVDHVVICAGQEPRRELADPLRAA
GKTVHLIGGCDVAMELDARRAIAQGTRLALEI
>Mature_671_residues
SYPSLFAPLDLGFTTLRNRVLMGSMHTGLEEHPDGAERLAAFYAERARHGVALIVTGGIAPVPSGVVMTGGAMLNDASQL
TPHRVVTDAVHAQGGKIALQILHTGRYSYQPHLVAPSAIQAPINRFMPHELTHDEILQLIDDFAHCAQLAREAGYDGVEV
MGSEGYLINEFLTRRTNHRDDEWGGDYASRMRFAVEVVRAVRQRVGNDFIIIYRLSMLDLVENGGTFDETVQLAQAIEAA
GASLINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSVPLIATNRINDPQVAETILTRGDADMVSMARPFLADAEFL
TKAQSGRADEINTCIGCNQACLDRIFIGKVTSCLVNPRACHETHMPITPAIRKKNLAVVGAGPAGLAFAINAASRGHHVT
LFDAQSEIGGQFTIARQIPGKEEFYETLRYYRRMIDVTGVTLKLNQRVNAEDLQPFDEAILACGIVPRRPPIDGIDHPKA
LTYLEVLRDKAPVGKRVAIIGCGGIGFDTAMYLSQHGESTSQNIAEFCTEWGIDTSLQQAGGLRPEGPRLARSPRQIVML
QRKTSKPGEGLGKTTGWIHRATLLARGVKMIPAVSYQKIDDDGLHLLIGGEPQLLEVDHVVICAGQEPRRELADPLRAAG
KTVHLIGGCDVAMELDARRAIAQGTRLALEI

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=672, Percent_Identity=85.7142857142857, Blast_Score=1202, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=358, Percent_Identity=29.8882681564246, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17559802, Length=223, Percent_Identity=27.3542600896861, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=217, Percent_Identity=26.7281105990783, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564188, Length=228, Percent_Identity=24.5614035087719, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559804, Length=220, Percent_Identity=24.0909090909091, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540738, Length=254, Percent_Identity=23.2283464566929, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=236, Percent_Identity=24.5762711864407, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=29.7777777777778, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321973, Length=223, Percent_Identity=27.8026905829596, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73131; Mature: 73000

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYPSLFAPLDLGFTTLRNRVLMGSMHTGLEEHPDGAERLAAFYAERARHGVALIVTGGI
CCCCCCCCCHHCCHHHHHHHHEECHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
APVPSGVVMTGGAMLNDASQLTPHRVVTDAVHAQGGKIALQILHTGRYSYQPHLVAPSAI
CCCCCCEEEECCHHCCCHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEECCHHH
QAPINRFMPHELTHDEILQLIDDFAHCAQLAREAGYDGVEVMGSEGYLINEFLTRRTNHR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
DDEWGGDYASRMRFAVEVVRAVRQRVGNDFIIIYRLSMLDLVENGGTFDETVQLAQAIEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHH
AGASLINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSVPLIATNRINDPQVAETIL
HCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
TRGDADMVSMARPFLADAEFLTKAQSGRADEINTCIGCNQACLDRIFIGKVTSCLVNPRA
HCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHH
CHETHMPITPAIRKKNLAVVGAGPAGLAFAINAASRGHHVTLFDAQSEIGGQFTIARQIP
HCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCHHCCCEEEEEECCC
GKEEFYETLRYYRRMIDVTGVTLKLNQRVNAEDLQPFDEAILACGIVPRRPPIDGIDHPK
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCH
ALTYLEVLRDKAPVGKRVAIIGCGGIGFDTAMYLSQHGESTSQNIAEFCTEWGIDTSLQQ
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
AGGLRPEGPRLARSPRQIVMLQRKTSKPGEGLGKTTGWIHRATLLARGVKMIPAVSYQKI
HCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCEEC
DDDGLHLLIGGEPQLLEVDHVVICAGQEPRRELADPLRAAGKTVHLIGGCDVAMELDARR
CCCCEEEEECCCCCEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHH
AIAQGTRLALEI
HHHCCCEEEEEC
>Mature Secondary Structure 
SYPSLFAPLDLGFTTLRNRVLMGSMHTGLEEHPDGAERLAAFYAERARHGVALIVTGGI
CCCCCCCCHHCCHHHHHHHHEECHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCC
APVPSGVVMTGGAMLNDASQLTPHRVVTDAVHAQGGKIALQILHTGRYSYQPHLVAPSAI
CCCCCCEEEECCHHCCCHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEECCHHH
QAPINRFMPHELTHDEILQLIDDFAHCAQLAREAGYDGVEVMGSEGYLINEFLTRRTNHR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCCC
DDEWGGDYASRMRFAVEVVRAVRQRVGNDFIIIYRLSMLDLVENGGTFDETVQLAQAIEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHH
AGASLINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSVPLIATNRINDPQVAETIL
HCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHH
TRGDADMVSMARPFLADAEFLTKAQSGRADEINTCIGCNQACLDRIFIGKVTSCLVNPRA
HCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCHH
CHETHMPITPAIRKKNLAVVGAGPAGLAFAINAASRGHHVTLFDAQSEIGGQFTIARQIP
HCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCEEEEEECCHHCCCEEEEEECCC
GKEEFYETLRYYRRMIDVTGVTLKLNQRVNAEDLQPFDEAILACGIVPRRPPIDGIDHPK
CHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCCCCH
ALTYLEVLRDKAPVGKRVAIIGCGGIGFDTAMYLSQHGESTSQNIAEFCTEWGIDTSLQQ
HHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHH
AGGLRPEGPRLARSPRQIVMLQRKTSKPGEGLGKTTGWIHRATLLARGVKMIPAVSYQKI
HCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCCCEEC
DDDGLHLLIGGEPQLLEVDHVVICAGQEPRRELADPLRAAGKTVHLIGGCDVAMELDARR
CCCCEEEEECCCCCEEEECEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHH
AIAQGTRLALEI
HHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]