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The map label for this gene is sopD

Identifier: 16766251

GI number: 16766251

Start: 3087148

End: 3088101

Strand: Direct

Name: sopD

Synonym: STM2945

Alternate gene names: 16766251

Gene position: 3087148-3088101 (Clockwise)

Preceding gene: 16766242

Following gene: 16766255

Centisome position: 63.56

GC content: 40.67

Gene sequence:

>954_bases
ATGCCAGTCACTTTAAGCTTCGGTAATCATCAAAATTATACGCTTAATGAAAGTCGGCTTGCTCATCTGTTAAGCGCAGA
TAAAGAAAAAGCAATCCATATGGGGGGTTGGGATAAAGTCCAGGATCATTTTAGAGCGGAAAAAAAGGACCATGCGCTGG
AAGTGTTACACTCCATCATTCACGGGCAGGGCCGTGGTGAACCTGGAGAGATGGAAGTTAACGTAGAGGATATAAATAAA
ATTTACGCCTTTAAACGGCTACAACATCTGGCCTGCCCGGCTCATCAAGATCTGTTTACTATCAAGATGGACGCTTCTCA
GACACAATTTTTACTTATGGTCGGCGACACGGTGATCAGCCAAAGCAATATTAAGGACATCCTTAATATATCAGATGATG
CAGTGATAGAATCTATGAGTAGAGAGGAGAGACAATTATTTTTACAAATATGTGAGGTGATTGGTTCGAAGATGACCTGG
CACCCGGAATTACTTCAGGAGTCGATTTCAACTCTACGAAAAGAAGTGACGGGAAATGCACAAATCAAAACGGCGGTTTA
TGAGATGATGCGTCCCGCAGAGGCTCCAGACCACCCGCTTGTCGAATGGCAGGACTCACTTACTGCAGATGAAAAATCAA
TGCTGGCCTGTATTAATGCCGGTAACTTTGAGCCTACGACTCAGTTTTGCAAAATAGGTTATCAGGAGGTACAAGGTGAA
GTCGCTTTTAGCATGATGCATCCGTGCATCTCCTATTTACTACATAGCTATTCACCGTTTTCAGAGTTTAAACCAACAAA
TTCTGGTTTTTTAAAAAAACTTAATCAGGATTATAACGACTATCATGCAAAAAAAATGTTTATTGATGTAATTCTTGAAA
AACTATATCTAACCCATGAACGTTCTTTGCACATTGGTAAAGATGGGTGCAGTCGTAATATATTACTGACATAA

Upstream 100 bases:

>100_bases
TCTCTCCTGTAGTAAACTTTATCTGTTTAATAAAAAAGAGAGAATTGAACGATATATTTTACTCCGGATATTGAATAATA
TAAATTTGAAGGAAAATATT

Downstream 100 bases:

>100_bases
AGATAGTCAGTAATATAACCAATTTAAAATCCGGCTGCCTGCCGGATTTTTCATAGCAGCAAGTATAATCATACCGCGTA
AGGACAATTACCCTTCATGC

Product: secreted effector protein

Products: NA

Alternate protein names: Salmonella outer protein D

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINK
IYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTW
HPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGE
VAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT

Sequences:

>Translated_317_residues
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINK
IYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTW
HPELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGE
VAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT
>Mature_316_residues
PVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKI
YAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWH
PELLQESISTLRKEVTGNAQIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGEV
AFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Contributes to replication in macrophages. Plays a role, cooperatively with sopB, in membrane fission and macropinosome formation during invasion

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm. Host cell membrane. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cell (Probable). Membrane-associated in transfected cells. Recruited to the bacterial invasion site, and

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sopD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SOPD_SALTY (P40722)

Other databases:

- EMBL:   M23007
- EMBL:   AE006468
- RefSeq:   NP_461866.1
- PRIDE:   P40722
- GeneID:   1254468
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2945
- NMPDR:   fig|99287.1.peg.2841
- HOGENOM:   HBG671701
- OMA:   RILNNIN
- ProtClustDB:   PRK15379
- BioCyc:   STYP99287:STM2945-MONOMER
- GO:   GO:0016020
- GO:   GO:0009405
- InterPro:   IPR022747
- ProDom:   PD040905

Pfam domain/function: PF11047 SopD

EC number: NA

Molecular weight: Translated: 36142; Mature: 36011

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSII
CCEEEECCCCCCCEECHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVIS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHH
QSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
VAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHE
HHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RSLHIGKDGCSRNILLT
CCEEECCCCCCCCCCCC
>Mature Secondary Structure 
PVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHFRAEKKDHALEVLHSII
CEEEECCCCCCCEECHHHHHHHHHCCHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
HGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIKMDASQTQFLLMVGDTVIS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCHHHH
QSNIKDILNISDDAVIESMSREERQLFLQICEVIGSKMTWHPELLQESISTLRKEVTGNA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QIKTAVYEMMRPAEAPDHPLVEWQDSLTADEKSMLACINAGNFEPTTQFCKIGYQEVQGE
HHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
VAFSMMHPCISYLLHSYSPFSEFKPTNSGFLKKLNQDYNDYHAKKMFIDVILEKLYLTHE
HHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
RSLHIGKDGCSRNILLT
CCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2670946; 11677609