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The map label for this gene is iroE [H]

Identifier: 16766088

GI number: 16766088

Start: 2922612

End: 2923547

Strand: Direct

Name: iroE [H]

Synonym: STM2776

Alternate gene names: 16766088

Gene position: 2922612-2923547 (Clockwise)

Preceding gene: 16766087

Following gene: 16766092

Centisome position: 60.17

GC content: 53.31

Gene sequence:

>936_bases
ATGTATGGTCGCCAGTACCACAACAAGCGCTATCGCATGGCGCTATTTTTAGTGAGTTTTTGTTTTAGCGCGCTGAGTTA
TGCGCAGCCGGATATGCAGCCATTAGGGCCGAATATCGCTGATAAAGGTTCGGGATATTACCATTTCAGGGTCAATGACT
TTCAATCTGCCGATGGCGCAAGACATTACCGGGTATGGACCGCTATCCCCAATAAAGCCGCCCCGCCGTCGGGTTATCCT
GTCTTATATATGCTGGACGGCAACGCAGTGATGGACAGACTGCCGGAGACGCTGCTCAAACAGCTGGCAGACCACTCGCC
GCCGGTGATTGTAGCGATTGGCTATCAGACTAACCTGCCGTTTGATCTTAACGGCAGAGCTTATGACTATACGCCGGCGC
CGGGAATCGATCGCGATGACAGTGAAAATAACCCGCGTTTTCATCGTAAAACCGGCGGCGGGCCAGCGTTCCGCCAGCTA
CTGGAGAGACATATCGCGCCGCAGGTGGAACAAGGAATAACCATCAACTCCGAACGGCGCGGGGTATGGGGACATTCTTA
TGGCGGCCTGTTCGTTTTAGACTCCTGGCTGTCGTCATCCTTCTTTCATATCTATTACAGCGCCAGCCCGTCACTCAGCA
GGGATAACTTTGTCCTGTTGAATCGCCTTACGACAGTGAAGCCGTCGCTGTTCTGCCATAAAAAACTCATCATAATGGAA
GGTTCAGCGTCGAATGGGGATAGCAGGCAACGCCAGATGGCCGAGCTCCTACAAAAAGTTCAGGAGACCGTGAGAACGCT
TGAGAACAACGGCGTTAACGCGGCCCTGCAGCATTACCCGGGCCTGGGCCACGGGCCCATGTTTAACGCCTCTTTTCGCA
GTGCATTGCTGGATATCAGTCGCGAACCGGCAAGCCAAAAACCACGCTGCCATTAA

Upstream 100 bases:

>100_bases
ACCGGCGGTCACGATTATGCCTGGTGGCGCGGCGCGCTGATTGACGGATTACGTCTACTGCCCCGATAAAACTTCACCTG
CCAAAAAGGAATAACATCCG

Downstream 100 bases:

>100_bases
CCCGCCGCCAGAATATGCCCGCCAGCGGCGGGCATAATCCATCAAAACGAGGCCGTCACACCGGCATAATAAGCCCGCCC
CGGTTCGTTATAGGTATTTG

Product: hydrolase

Products: NA

Alternate protein names: Bacillibactin trilactone hydrolase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MYGRQYHNKRYRMALFLVSFCFSALSYAQPDMQPLGPNIADKGSGYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGYP
VLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLPFDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQL
LERHIAPQVEQGITINSERRGVWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFVLLNRLTTVKPSLFCHKKLIIME
GSASNGDSRQRQMAELLQKVQETVRTLENNGVNAALQHYPGLGHGPMFNASFRSALLDISREPASQKPRCH

Sequences:

>Translated_311_residues
MYGRQYHNKRYRMALFLVSFCFSALSYAQPDMQPLGPNIADKGSGYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGYP
VLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLPFDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQL
LERHIAPQVEQGITINSERRGVWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFVLLNRLTTVKPSLFCHKKLIIME
GSASNGDSRQRQMAELLQKVQETVRTLENNGVNAALQHYPGLGHGPMFNASFRSALLDISREPASQKPRCH
>Mature_311_residues
MYGRQYHNKRYRMALFLVSFCFSALSYAQPDMQPLGPNIADKGSGYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGYP
VLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLPFDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQL
LERHIAPQVEQGITINSERRGVWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFVLLNRLTTVKPSLFCHKKLIIME
GSASNGDSRQRQMAELLQKVQETVRTLENNGVNAALQHYPGLGHGPMFNASFRSALLDISREPASQKPRCH

Specific function: Catalyzes the hydrolysis of the trilactone cycle of ferri-bacillibactin (ferri-BB) complex, leading to the formation of bacillibactin monomers and to cytosolic iron release, thus making iron available for metabolic use. Can also hydrolyze bacillibactin (B

COG id: COG2819

COG function: function code R; Predicted hydrolase of the alpha/beta superfamily

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 34995; Mature: 34995

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGRQYHNKRYRMALFLVSFCFSALSYAQPDMQPLGPNIADKGSGYYHFRVNDFQSADGA
CCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
RHYRVWTAIPNKAAPPSGYPVLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLP
EEEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
FDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQLLERHIAPQVEQGITINSERR
EECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHCCCEECCCCC
GVWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFVLLNRLTTVKPSLFCHKKLIIME
CCCCCCCCCCEEEEHHHCCCEEEEEEECCCCCCCCCEEEEEHHHHCCCHHHCCEEEEEEE
GSASNGDSRQRQMAELLQKVQETVRTLENNGVNAALQHYPGLGHGPMFNASFRSALLDIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
REPASQKPRCH
CCCCCCCCCCC
>Mature Secondary Structure
MYGRQYHNKRYRMALFLVSFCFSALSYAQPDMQPLGPNIADKGSGYYHFRVNDFQSADGA
CCCCHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
RHYRVWTAIPNKAAPPSGYPVLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLP
EEEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
FDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQLLERHIAPQVEQGITINSERR
EECCCCEEECCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHCCCHHHCCCEECCCCC
GVWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFVLLNRLTTVKPSLFCHKKLIIME
CCCCCCCCCCEEEEHHHCCCEEEEEEECCCCCCCCCEEEEEHHHHCCCHHHCCEEEEEEE
GSASNGDSRQRQMAELLQKVQETVRTLENNGVNAALQHYPGLGHGPMFNASFRSALLDIS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
REPASQKPRCH
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]