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The map label for this gene is srlA [H]

Identifier: 16766062

GI number: 16766062

Start: 2889221

End: 2889742

Strand: Direct

Name: srlA [H]

Synonym: STM2750

Alternate gene names: 16766062

Gene position: 2889221-2889742 (Clockwise)

Preceding gene: 16766061

Following gene: 16766063

Centisome position: 59.48

GC content: 59.58

Gene sequence:

>522_bases
ATGTTTCTGGTCTCCCTGGCTGAAGGCTTTATCCACCTGTTCCAGGCCGCAGGCAAAATCTTTCTCGACATGATGACCGG
GCTTATCCCGATGCTCATCTGCCTGCTGCTGGCCATCAATTTCCTGATGAAGCTGGTCGGTACCGTCAGAATGGAGAAGG
TCGCTGCCCTGCTCGGCCGCTCGCGCATTCTCACCTACGGCGTGTTGCCGGTGCTCGGCTGGTTCTTTATGAGCAGCCCC
GGCGCGCTGACGCTCGGTAAGCTCTTACCTGAGAAGAGTAAACCCGGCTATGAAGATGCGCTCGGCACCACCGCCCATCC
CCTCACCAGCCTGTTTCCCCACGTAGTGCCATCAGAGCTGTTTGTCTGGCTCGGCGTGGCTGCGGGGGTTAAGGCACTCG
GTCTGCCCGTTACTTCACTGGCGCTGCGCTATATCGCCGCCGCCATGCTAATTGGCCTGATACGCGGGATTATCACCGAG
TACCTGTTCCTGCGGCTCAGCAGGCGGGGGAATGCGCCATGA

Upstream 100 bases:

>100_bases
TGAGTGGCAGGACGCATTAACCAACGACACCTGACAGGAGAGTTGTTTATGCACACCGAACCACAACCATGCACCATCGC
ACCACTCGCAGGAGGCCGCC

Downstream 100 bases:

>100_bases
TGATTTACTGCGCACGTATTACTGCCATCGGGCTGTTTGTCGCCGACGGCCTCACCGACAAGATGCTCATCACCTTCGAC
AGCAACGGGCCGAAGGACTG

Product: PTS system glucitol/sorbitol-specific enzyme II

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSRRGNAP

Sequences:

>Translated_173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSRRGNAP
>Mature_173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSRRGNAP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=154, Percent_Identity=40.2597402597403, Blast_Score=129, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18712; Mature: 18712

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSEL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
FVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSRRGNAP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGTVRMEKVAALLGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSEL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
FVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSRRGNAP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]