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The map label for this gene is sppA [H]

Identifier: 16765926

GI number: 16765926

Start: 2752336

End: 2753832

Strand: Reverse

Name: sppA [H]

Synonym: STM2605

Alternate gene names: 16765926

Gene position: 2753832-2752336 (Counterclockwise)

Preceding gene: 16765927

Following gene: 16765925

Centisome position: 56.69

GC content: 56.58

Gene sequence:

>1497_bases
GTGCAACGTAATCTCTCGCACATCATCAGCCAGGCAACCAGTGCTCCGTTGCTGCTTGAACCCGCCTATGCGCGGGTTTT
CTTTTGCGCGCTGGGCAGGGAGTCAGGCATTAACAGCCTGCACATTCCCGGTAATAACGAAAGTCTGGATCAGTCGGATA
TGGCACTGGTCACAGGCGATTTTATGGCGACCGGAAAGCCGCAGGCACGTTTTTATCAGGTAGTGAACGGTATTGCGGTA
TTACCCGTGACCGGAACACTGGTTCATAAACTCGGCGGAATGCGTCCCTTTTCAGGGATGACCGGATATGACGGTGTCAC
TGCCCGGCTACAACAGGCGGTTTCAGATCCGGAGGTAAAAGGCATTCTGCTGGATATTGACAGTCCCGGCGGTCAGGCTG
CCGGGGCGTTTGACTGTGCTGACATGATTTACCGGATGCGCGAACAGAAACCTGTCTGGGCACTGGCAAATGAAACAGCC
TGTTCGGCGGCCATGTTGCTGGCGGCAGCCTGTTCGCACCGCCTTGTGACCCAGACGTCCAGAATGGGATCAATTGGTGT
GGTGATGGCGCATACCAGCTACGCCGAAAAACTGAAACAGGAAGGGATCGATATCACCCTTATCTATTCTGGCGCACACA
AGGCTGATCTGACGCCCAGCCAGAAATTACCGGAAAGTGTCTATGCCGACTACCAGCAGCGAATGGACGAGGCCAGAAAG
ATGTTTGCAGAAAAAGTGGCCCGGTACACGGGGTTGTCTGTCGATGCGGTAATGGCGACGGAGGCGGCAGTGTATGACGG
GCAGGCCATTATCACTACCGGACTGGCAGATGGAATGGTGAATGCTGCTGACGCCATCGGCGTGATGGCAGAAGCTATCA
ACAGTAACAAGACAGGAGGCACTATGCCTGAATTAAGTGCAGCTGACGCTGTCACGCAGGAAAACCAGCGCGTAATGGGA
ATTCTGGGTTGCCCGGAGGCCAGGGGGCATGAGGCACTGGCACAGATGCTGGCCGGGCAGCCGGGAATGAGCGTTGCTCA
GGCGAAGTCTATTCTGGCTGCCGCCGCGCCGGCGGACACGACCAGCACCGCTGACCGTATCCTTGCCCTGGAAGAAGCTG
GTGGTCGGGAAACACTCGCACAGACACTGGCGGCCATGCCAGAGATGACGGTGGAACAGGCCAGAACCATTCTGGCAGCA
TCGCCGATCGCTGCGGCAACGTCACTTCATGATGCCGTGATGGCGCTTGATGAGGCGAAAGGCCGTGAAGAGTTGGCGGA
AAAACTGGCTGTCATGCCTGGTATGACCACAGATCAGGCCCGTGACCTGCTGGCTGCCGCGCCGGACAAATCCGGTAATG
CGGGGCTGAGCATGAACAACGCATTTGATGCTTTCATGCAGTCTCATTCCCCGGGCCCCATATCCGGCGGCAAAGGCCAC
AGTAATGATACCGAAACGACGTTGTTGATGAGTATTCCCGGTACTTCAGCCACCTGA

Upstream 100 bases:

>100_bases
TCCGAAGAACGGCGGGCAGCCGGACTTTCGCGTCCGGTATGGATCACTGATACCTATCAACAACAGATCGCGGCGAGCCG
TCAGACGGAGGAGGAAAAGC

Downstream 100 bases:

>100_bases
TAAGGAGACAGTATGTCATTTACCACCACTATTGAGAAACGTGCGGATAACCGCATTTTCGCCGGTAACGATCCGGCACA
TACCGCAACGGGAGTCAGCG

Product: head-tail preconnector-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MQRNLSHIISQATSAPLLLEPAYARVFFCALGRESGINSLHIPGNNESLDQSDMALVTGDFMATGKPQARFYQVVNGIAV
LPVTGTLVHKLGGMRPFSGMTGYDGVTARLQQAVSDPEVKGILLDIDSPGGQAAGAFDCADMIYRMREQKPVWALANETA
CSAAMLLAAACSHRLVTQTSRMGSIGVVMAHTSYAEKLKQEGIDITLIYSGAHKADLTPSQKLPESVYADYQQRMDEARK
MFAEKVARYTGLSVDAVMATEAAVYDGQAIITTGLADGMVNAADAIGVMAEAINSNKTGGTMPELSAADAVTQENQRVMG
ILGCPEARGHEALAQMLAGQPGMSVAQAKSILAAAAPADTTSTADRILALEEAGGRETLAQTLAAMPEMTVEQARTILAA
SPIAAATSLHDAVMALDEAKGREELAEKLAVMPGMTTDQARDLLAAAPDKSGNAGLSMNNAFDAFMQSHSPGPISGGKGH
SNDTETTLLMSIPGTSAT

Sequences:

>Translated_498_residues
MQRNLSHIISQATSAPLLLEPAYARVFFCALGRESGINSLHIPGNNESLDQSDMALVTGDFMATGKPQARFYQVVNGIAV
LPVTGTLVHKLGGMRPFSGMTGYDGVTARLQQAVSDPEVKGILLDIDSPGGQAAGAFDCADMIYRMREQKPVWALANETA
CSAAMLLAAACSHRLVTQTSRMGSIGVVMAHTSYAEKLKQEGIDITLIYSGAHKADLTPSQKLPESVYADYQQRMDEARK
MFAEKVARYTGLSVDAVMATEAAVYDGQAIITTGLADGMVNAADAIGVMAEAINSNKTGGTMPELSAADAVTQENQRVMG
ILGCPEARGHEALAQMLAGQPGMSVAQAKSILAAAAPADTTSTADRILALEEAGGRETLAQTLAAMPEMTVEQARTILAA
SPIAAATSLHDAVMALDEAKGREELAEKLAVMPGMTTDQARDLLAAAPDKSGNAGLSMNNAFDAFMQSHSPGPISGGKGH
SNDTETTLLMSIPGTSAT
>Mature_498_residues
MQRNLSHIISQATSAPLLLEPAYARVFFCALGRESGINSLHIPGNNESLDQSDMALVTGDFMATGKPQARFYQVVNGIAV
LPVTGTLVHKLGGMRPFSGMTGYDGVTARLQQAVSDPEVKGILLDIDSPGGQAAGAFDCADMIYRMREQKPVWALANETA
CSAAMLLAAACSHRLVTQTSRMGSIGVVMAHTSYAEKLKQEGIDITLIYSGAHKADLTPSQKLPESVYADYQQRMDEARK
MFAEKVARYTGLSVDAVMATEAAVYDGQAIITTGLADGMVNAADAIGVMAEAINSNKTGGTMPELSAADAVTQENQRVMG
ILGCPEARGHEALAQMLAGQPGMSVAQAKSILAAAAPADTTSTADRILALEEAGGRETLAQTLAAMPEMTVEQARTILAA
SPIAAATSLHDAVMALDEAKGREELAEKLAVMPGMTTDQARDLLAAAPDKSGNAGLSMNNAFDAFMQSHSPGPISGGKGH
SNDTETTLLMSIPGTSAT

Specific function: Digestion of cleaved signal peptides. Required for efficient processing of precursors under conditions of hyper-secretion [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52023; Mature: 52023

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRNLSHIISQATSAPLLLEPAYARVFFCALGRESGINSLHIPGNNESLDQSDMALVTGD
CCCCHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEECC
FMATGKPQARFYQVVNGIAVLPVTGTLVHKLGGMRPFSGMTGYDGVTARLQQAVSDPEVK
HHCCCCCHHHHHHHHCCCEEEECHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GILLDIDSPGGQAAGAFDCADMIYRMREQKPVWALANETACSAAMLLAAACSHRLVTQTS
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RMGSIGVVMAHTSYAEKLKQEGIDITLIYSGAHKADLTPSQKLPESVYADYQQRMDEARK
CCCCCEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
MFAEKVARYTGLSVDAVMATEAAVYDGQAIITTGLADGMVNAADAIGVMAEAINSNKTGG
HHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHHHHHHHCCCCCCC
TMPELSAADAVTQENQRVMGILGCPEARGHEALAQMLAGQPGMSVAQAKSILAAAAPADT
CCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
TSTADRILALEEAGGRETLAQTLAAMPEMTVEQARTILAASPIAAATSLHDAVMALDEAK
CHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GREELAEKLAVMPGMTTDQARDLLAAAPDKSGNAGLSMNNAFDAFMQSHSPGPISGGKGH
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SNDTETTLLMSIPGTSAT
CCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MQRNLSHIISQATSAPLLLEPAYARVFFCALGRESGINSLHIPGNNESLDQSDMALVTGD
CCCCHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCEEEECC
FMATGKPQARFYQVVNGIAVLPVTGTLVHKLGGMRPFSGMTGYDGVTARLQQAVSDPEVK
HHCCCCCHHHHHHHHCCCEEEECHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GILLDIDSPGGQAAGAFDCADMIYRMREQKPVWALANETACSAAMLLAAACSHRLVTQTS
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHH
RMGSIGVVMAHTSYAEKLKQEGIDITLIYSGAHKADLTPSQKLPESVYADYQQRMDEARK
CCCCCEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHH
MFAEKVARYTGLSVDAVMATEAAVYDGQAIITTGLADGMVNAADAIGVMAEAINSNKTGG
HHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECHHHCHHHHHHHHHHHHHHHCCCCCCC
TMPELSAADAVTQENQRVMGILGCPEARGHEALAQMLAGQPGMSVAQAKSILAAAAPADT
CCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
TSTADRILALEEAGGRETLAQTLAAMPEMTVEQARTILAASPIAAATSLHDAVMALDEAK
CHHHHHEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GREELAEKLAVMPGMTTDQARDLLAAAPDKSGNAGLSMNNAFDAFMQSHSPGPISGGKGH
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
SNDTETTLLMSIPGTSAT
CCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10455123 [H]