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The map label for this gene is hcaT [H]

Identifier: 16765874

GI number: 16765874

Start: 2692346

End: 2693485

Strand: Reverse

Name: hcaT [H]

Synonym: STM2554

Alternate gene names: 16765874

Gene position: 2693485-2692346 (Counterclockwise)

Preceding gene: 16765875

Following gene: 16765872

Centisome position: 55.45

GC content: 58.25

Gene sequence:

>1140_bases
ATGGCATTGCATTCCACGCGCTGGCTGGCGCTCAGTTATTTCACCTACTTCTTTAGTTACGGTATTTTTCTGCCCTTCTG
GAGCGTCTGGCTCAAAGGTCTTGGGCTAACGCCGGAAACCATCGGTCTTCTGCTGGGCGTGGGTCTGGTCGCGCGTTTTC
TCGGTAGTCTGCTCATTGCGCCTCGCGTAAGCGATCCTTCGCGGTTGATCTCCGCGCTGCGCGTCCTGGCATTGCTGACG
CTGGTATTTGCGCTGGCATTTTGGGCAGGAACGCATGTCGCGTGGCTAATGGTGGTGATGGTTGGGTTTAACCTCTTCTT
TTCGCCACTGGTGCCGCTGACCGATGCGCTGGCCAATACCTGGCAAAAGCAAATTACCCTGGACTATGGTCGGGTGCGGC
TGTGGGGGTCCATCGCCTTCGTGATAGGGTCGGCGCTGACCGGTAAGCTGGTGAGTTTATACGATTACCAGGCGATTCTG
GCGCTACTGACGCTCGGCGTCGCCTCGATGTTGCTGGGTATGTTGTTACGTCCCAGCGTGCCGCCGCAAGGGGAAAGCCG
TCAGCAGGAGAGCGCAGGCTGGCCCGCCTGGCGTACGCTGGTGGCACAAAGTTGGCGTTTTCTCGCCTGCGTCTGTTTGC
TGCAAGGGGCGCACGCCGCCTACTACGGTTTTAGCGCCATCTACTGGCAGGGGGCTGGCTATTCAGCATCGGCGGTCGGC
TATTTATGGTCGTTGGGCGTGGTGGCGGAAGTGATCATTTTCGCCCTGAGTAAAAAGCTATTCCGCCGGTTTAGCGCCCG
CGACTTGCTGTTGCTTTCCGCTGTGTGCGGCGTGGTACGCTGGGGACTGATGGGCTGGAGTACGGCGTTGCCGTGGCTGA
TTGTGATACAAATCCTGCACTGTGGCACGTTTACCGTTTGCCATCTGGCCGCCATGCGCTATATCGCTGCGCGTCAGGGA
AGCGAGGTGATTCGTTTGCAGGCCGTCTATTCCGCTGTGGCGATGGGCGGCAGTATCGCGATTATGACGGTATTTGCCGG
TTTTCTGTATCAACATCTGGGCGGCGGCGTATTCTGGATTATGGCGCTGGTGGCATTGCCCGCTATCTTCCTTCGGCCCA
AAGTGGTTGCCGCGTCATGA

Upstream 100 bases:

>100_bases
CGTTGCCGTTTGAACTTCTCCCTCCGCCTGTTAACCTTATGTTACCCTTGCCAGCGCAACCGTTTACCGCCAGACTATCG
CCTCCAAACGGGAGGGAATC

Downstream 100 bases:

>100_bases
TTCCAGGATCTTGCGGATCTGCTGCTGTTGGTGCTCTGTGAGGGCGCGATCCGCATGAATTAACGGCGGTGAGAAGAGCG
GTAGCGGCGTGGCGTAAGGG

Product: 3-phenylpropionic acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLLLGVGLVARFLGSLLIAPRVSDPSRLISALRVLALLT
LVFALAFWAGTHVAWLMVVMVGFNLFFSPLVPLTDALANTWQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAIL
ALLTLGVASMLLGMLLRPSVPPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAHAAYYGFSAIYWQGAGYSASAVG
YLWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVCGVVRWGLMGWSTALPWLIVIQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLGGGVFWIMALVALPAIFLRPKVVAAS

Sequences:

>Translated_379_residues
MALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLLLGVGLVARFLGSLLIAPRVSDPSRLISALRVLALLT
LVFALAFWAGTHVAWLMVVMVGFNLFFSPLVPLTDALANTWQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAIL
ALLTLGVASMLLGMLLRPSVPPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAHAAYYGFSAIYWQGAGYSASAVG
YLWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVCGVVRWGLMGWSTALPWLIVIQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLGGGVFWIMALVALPAIFLRPKVVAAS
>Mature_378_residues
ALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLLLGVGLVARFLGSLLIAPRVSDPSRLISALRVLALLTL
VFALAFWAGTHVAWLMVVMVGFNLFFSPLVPLTDALANTWQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAILA
LLTLGVASMLLGMLLRPSVPPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAHAAYYGFSAIYWQGAGYSASAVGY
LWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVCGVVRWGLMGWSTALPWLIVIQILHCGTFTVCHLAAMRYIAARQGS
EVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLGGGVFWIMALVALPAIFLRPKVVAAS

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=376, Percent_Identity=88.031914893617, Blast_Score=646, Evalue=0.0,
Organism=Escherichia coli, GI1788415, Length=335, Percent_Identity=25.6716417910448, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 41457; Mature: 41326

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
ALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLLLGVGLVARFLGSLLIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
PRVSDPSRLISALRVLALLTLVFALAFWAGTHVAWLMVVMVGFNLFFSPLVPLTDALANT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAILALLTLGVASMLLGMLLRPSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAHAAYYGFSAIYWQGAGYSASAVG
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHEECCCCCCHHHHH
YLWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVCGVVRWGLMGWSTALPWLIVIQILH
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQHLGGGVFWI
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHH
MALVALPAIFLRPKVVAAS
HHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]