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The map label for this gene is asrB

Identifier: 16765869

GI number: 16765869

Start: 2687490

End: 2688308

Strand: Direct

Name: asrB

Synonym: STM2549

Alternate gene names: 16765869

Gene position: 2687490-2688308 (Clockwise)

Preceding gene: 16765868

Following gene: 16765870

Centisome position: 55.33

GC content: 55.56

Gene sequence:

>819_bases
ATGTCACATTGTTCCTGTCATGATAAACCGCAGCACAGTTTGCTGCCTGCGGCGTACCGCATCCTCAGTATTACTCGCCA
CACGCCGCTGGAGTGGAATTTCCGCGTGGCCGTCGATTTTCCCGCGCACTGGGGGCAATTTGTTGAGGTGTCGCTGCCGC
GCGTCGGCGAAGCGCCCATCTCCGTTTCCGACTACGGCGACGGCTGGATAGATCTGCTGATTCGTAATGTCGGAAAAGTG
ACCAGCGCCCTCTTTACGCTGAAAGAAGGCGACAACGTGTGGCTACGCGGCTGCTATGGCAATGGCTATCCGGTCGATAC
GCTGCGCCATAAGCCCTTACTGGTTGTCGCAGGCGGTACGGGCGTCGCGCCGGTGAAAGGCTTAATGCGCTATTTCGTTG
AGAATCCCCAGGAAATTGGTCAACTGGATATGATTCTCGGCTATAAAAATCGCGATTGCGTGCTGTACAAAGAAGAAATG
GCGACGTGGCGCGGCAAACATAATCTGGTACTCACGCTGGATGAAGGCGAGGCTGATGACCGTTACCAGATTGGCCGGGT
GACCGATCGGCTTGCCGACATGACGCTTAGCGATATCGACACTATGCAGGCCATCGTCGTTGGGCCGCCAATAATGATTA
CCTTTACCGTAAAAATGCTGCTGCAAAAAGGGCTCAAGCCGGAGCAAATCTGGGTGGACTACGAACGCCGGATGGCCTGC
TCCGTCGGGAAGTGCGGCCACTGCCGTATGGGCGAAGTGTATGTCTGCACCGACGGTCCGATATTTAACTACGCCGTCGC
GCAACGTTTTGCCGATTAA

Upstream 100 bases:

>100_bases
CCGCTGCGACGATCGCTGCCCGCAATACATCAAATTTTCTTTGATTATCAACAAAATGACCGCTGCCGTTCGGCAGGCGC
TGGCAGAGGAGGCATAACGC

Downstream 100 bases:

>100_bases
GGAGAACATCATGAGCATTGATATTGATATCATTAAAGCCCGTGCGAAAAACGAATATCGCCTGTCAAAAGTGCGCGGCG
AAGCCATGATCAGCGTCCGC

Product: anaerobic sulfite reductase subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKV
TSALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEM
ATWRGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMAC
SVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD

Sequences:

>Translated_272_residues
MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKV
TSALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEM
ATWRGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMAC
SVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD
>Mature_271_residues
SHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKVT
SALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEMA
TWRGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMACS
VGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASRB_SALTY (P26475)

Other databases:

- EMBL:   M57706
- EMBL:   AE006468
- PIR:   B38453
- RefSeq:   NP_461484.1
- ProteinModelPortal:   P26475
- SMR:   P26475
- PRIDE:   P26475
- GeneID:   1254071
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2549
- HOGENOM:   HBG730970
- OMA:   LERRMHC
- ProtClustDB:   PRK08221
- BioCyc:   MetaCyc:MONOMER-12545
- BioCyc:   STYP99287:STM2549-MONOMER
- GO:   GO:0005737
- GO:   GO:0006810
- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- InterPro:   IPR014260
- PIRSF:   PIRSF006816
- TIGRFAMs:   TIGR02911

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1; SSF63380 Riboflavin_synthase_like_b-brl

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30610; Mature: 30479

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS51384 FAD_FR

Important sites: BINDING 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCE
SVSDYGDGWIDLLIRNVGKVTSALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGT
EECCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCC
GVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEMATWRGKHNLVLTLDEGEADD
CCHHHHHHHHHHHCCHHHHCCEEEEEECCCCCEEEEHHHHHHHCCCCCEEEEECCCCCCC
RYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMAC
CEEHHHHHHHHHHCHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCHHHEEEEHHHHHHH
SVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD
CCCCCCCCCCCCEEEECCCCEEHHHHHHHHCC
>Mature Secondary Structure 
SHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHWGQFVEVSLPRVGEAPI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCE
SVSDYGDGWIDLLIRNVGKVTSALFTLKEGDNVWLRGCYGNGYPVDTLRHKPLLVVAGGT
EECCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEECCC
GVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEMATWRGKHNLVLTLDEGEADD
CCHHHHHHHHHHHCCHHHHCCEEEEEECCCCCEEEEHHHHHHHCCCCCEEEEECCCCCCC
RYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVKMLLQKGLKPEQIWVDYERRMAC
CEEHHHHHHHHHHCHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCHHHEEEEHHHHHHH
SVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD
CCCCCCCCCCCCEEEECCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1704886; 11677609