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The map label for this gene is yfhR

Identifier: 16765867

GI number: 16765867

Start: 2685383

End: 2686261

Strand: Direct

Name: yfhR

Synonym: STM2547

Alternate gene names: 16765867

Gene position: 2685383-2686261 (Clockwise)

Preceding gene: 16765866

Following gene: 16765868

Centisome position: 55.28

GC content: 51.99

Gene sequence:

>879_bases
ATGACCCTTCAACATACCCGACGCATCGTCAAATCCCTTTTTATTCTGTTTATCATTGTGGTCTGTATTTATCTGCTACC
CCGCGTAGCGATCAATGCCTTTTATTACCCGGACAATAAAGTCTATGGGCCAACCCCTGCCGAAGCTGAATCCATTACCT
TTACCGCCAAAGATGGCACGCATCTGCACGGCTGGTTTATTCCCACTGCTTTCGGCAGGCCGGAAAACGCCGTCGCGACG
GTGATTCATGTCCATGGCAACGCCGGAAATATGTCGGCGCACTGGCCGTTAGTCAGTTGGCTGCCAGAACGCAACGTAAA
CCTGTTTATGTTTGATTACCGTGGTTTTGGCGAATCTGAGGGCACCCCATCACAAGAGGGGCTACTGGACGATACGAAAA
GCGCGATAGATTATGTGCGGCATCGCGCCGACGTTAACCCCGAGCGCCTGGTACTGCTGGGGCAGAGCCTGGGCGGCAAT
AATGTACTGGCCGCCGTAGGCCACTGCGTAGGCTGCGCAAATATGCGCTACGCCGACCAGGCGGGCATACGTGCGATTAT
CCTTGACTCAACGTTTTTATCCTATTCCTCCATCGCCAACCAGATGATCCCGGGCAGCGGCTATTTGCTTGATGACCGCT
ATAGCGCGGATCGCAATATTGCCAGCGTCAGCCCCATTCCGGTATTGATTCTTCATGGCACGGCAGACCATGTTATTCCC
TGGCAGGACAGTGAGAAATTGTATGCCCTCGCCCGGGAGCCCAAACAAAAAATCTTCATTCCTGACGGCGATCACATTGA
TGCTTTTTCCGGACGTTATGCAAACCTTTACCGTGATGCAATGATTAAATTTATTCAGACCGCGCTATCCGCTAAATAG

Upstream 100 bases:

>100_bases
GCGTTTTTCCTAAACACAGCCTCATCGCTTTACTTGCCTGCATGTTTTTGTACGATCGCTCCCTGCTCCGCTATTGGCAT
AAAGCGGCAAGGAAGCGAAC

Downstream 100 bases:

>100_bases
CGCGACGCTGTATATATGCATATTTTATGATTAAGAATATATTTATTATACCGATAGTAAAAACCATTTTTTCCCGTTAG
CGAAGGCGGTGGATTAGCGC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGPTPAEAESITFTAKDGTHLHGWFIPTAFGRPENAVAT
VIHVHGNAGNMSAHWPLVSWLPERNVNLFMFDYRGFGESEGTPSQEGLLDDTKSAIDYVRHRADVNPERLVLLGQSLGGN
NVLAAVGHCVGCANMRYADQAGIRAIILDSTFLSYSSIANQMIPGSGYLLDDRYSADRNIASVSPIPVLILHGTADHVIP
WQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANLYRDAMIKFIQTALSAK

Sequences:

>Translated_292_residues
MTLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGPTPAEAESITFTAKDGTHLHGWFIPTAFGRPENAVAT
VIHVHGNAGNMSAHWPLVSWLPERNVNLFMFDYRGFGESEGTPSQEGLLDDTKSAIDYVRHRADVNPERLVLLGQSLGGN
NVLAAVGHCVGCANMRYADQAGIRAIILDSTFLSYSSIANQMIPGSGYLLDDRYSADRNIASVSPIPVLILHGTADHVIP
WQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANLYRDAMIKFIQTALSAK
>Mature_291_residues
TLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGPTPAEAESITFTAKDGTHLHGWFIPTAFGRPENAVATV
IHVHGNAGNMSAHWPLVSWLPERNVNLFMFDYRGFGESEGTPSQEGLLDDTKSAIDYVRHRADVNPERLVLLGQSLGGNN
VLAAVGHCVGCANMRYADQAGIRAIILDSTFLSYSSIANQMIPGSGYLLDDRYSADRNIASVSPIPVLILHGTADHVIPW
QDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANLYRDAMIKFIQTALSAK

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine esterase family

Homologues:

Organism=Homo sapiens, GI49355781, Length=274, Percent_Identity=30.6569343065693, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI71051600, Length=226, Percent_Identity=30.0884955752212, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI109689718, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI24308097, Length=198, Percent_Identity=29.7979797979798, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71051602, Length=199, Percent_Identity=30.1507537688442, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI151301175, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI194306564, Length=218, Percent_Identity=28.4403669724771, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI32451492, Length=209, Percent_Identity=29.1866028708134, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI194306562, Length=218, Percent_Identity=28.4403669724771, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32528310, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI226510965, Length=292, Percent_Identity=66.4383561643836, Blast_Score=419, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI71988362, Length=194, Percent_Identity=25.7731958762887, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=280, Percent_Identity=26.4285714285714, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17137566, Length=282, Percent_Identity=28.0141843971631, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281362521, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281362519, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571878, Length=264, Percent_Identity=25.3787878787879, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFHR_SALTY (Q8ZN39)

Other databases:

- EMBL:   AE006468
- RefSeq:   NP_461482.1
- ProteinModelPortal:   Q8ZN39
- GeneID:   1254069
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2547
- HOGENOM:   HBG527688
- OMA:   IRYTGDS
- ProtClustDB:   CLSK880424
- BioCyc:   STYP99287:STM2547-MONOMER
- InterPro:   IPR001375

Pfam domain/function: PF00326 Peptidase_S9

EC number: NA

Molecular weight: Translated: 32364; Mature: 32233

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf92499c)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGPTPAEAESITFTAKDGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCC
HLHGWFIPTAFGRPENAVATVIHVHGNAGNMSAHWPLVSWLPERNVNLFMFDYRGFGESE
EEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHECCCCCCCEEEEEECCCCCCCC
GTPSQEGLLDDTKSAIDYVRHRADVNPERLVLLGQSLGGNNVLAAVGHCVGCANMRYADQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCC
AGIRAIILDSTFLSYSSIANQMIPGSGYLLDDRYSADRNIASVSPIPVLILHGTADHVIP
CCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEC
WQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANLYRDAMIKFIQTALSAK
CCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGPTPAEAESITFTAKDGT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEEECCCC
HLHGWFIPTAFGRPENAVATVIHVHGNAGNMSAHWPLVSWLPERNVNLFMFDYRGFGESE
EEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCHHECCCCCCCEEEEEECCCCCCCC
GTPSQEGLLDDTKSAIDYVRHRADVNPERLVLLGQSLGGNNVLAAVGHCVGCANMRYADQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCC
AGIRAIILDSTFLSYSSIANQMIPGSGYLLDDRYSADRNIASVSPIPVLILHGTADHVIP
CCCEEEEECCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCEEC
WQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANLYRDAMIKFIQTALSAK
CCCCCHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677609