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The map label for this gene is dmsB [H]

Identifier: 16765849

GI number: 16765849

Start: 2662287

End: 2662916

Strand: Reverse

Name: dmsB [H]

Synonym: STM2529

Alternate gene names: 16765849

Gene position: 2662916-2662287 (Counterclockwise)

Preceding gene: 16765850

Following gene: 16765848

Centisome position: 54.82

GC content: 53.97

Gene sequence:

>630_bases
ATGAGTCAGTTTACACATTACCCGCCGGTGAGCGATAAACAACTGGGATTTTTCATCGACTCCTCACGCTGCTCCGGTTG
TAAAGCCTGCCAGGTGGCCTGCAAAGACAAAAACAATCTGGAAGTAGGCCGTCGTTTCCGCCGCGTCTATGAAGTCAAGG
GCGGAAGTTTCATCCCGACCGGGCAGGGTGGGGTCAGCAATAACGTATTTGCTTATACGCTTTCCATTTCCTGCAACCAC
TGTGCGGACCCTGTCTGCACCAAAAATTGCCCGACTACCGCTATGCATAAACGCCCGGGTGACGGCATTGTGCGCGTTGA
TACCGACAAATGCGTCGGCTGTGGCTATTGCGCCTGGTCCTGCCCTTATGGCGCGCCGCAGCTTAACGAGCAGACCGGCC
AAATGTCTAAGTGCGACATGTGCGTTGATTTACTGGCGAAAGGTGAACCGCCCGTCTGTGTTGCGACCTGTCCGCTGGAG
GCCATCAAGTTTGGTCCGATTGATGAACTGCGCGCGAAGTACGGTAGCGTATGCGACGTTAACGGGCTGCCAGATTCATC
CATAACCAAACCTAATCTGGTTGTCAAAGCGCATCAGGGCGCAGAAAAAGAGGGTAAACGCCATGCATGA

Upstream 100 bases:

>100_bases
TTGATAAAGGCGGCTGTGCGAACGTCCTCAGCTCGGCCCGTATTACCGCGCTGGCGAAGGGAAATTCACATCAAACCATG
CTGGTGGAGGTGGCTAAAGC

Downstream 100 bases:

>100_bases
GTTACCGCTGCTGATTTTTACGCTCTGTTTGCAAGGGTCCGTGGGCGTGACAGTGTGGCTGGCGTTGGGCCGCCAGTACG
CCGTAGAGGGACGCGTGCCT

Product: anaerobic dimethylsulfoxide reductase

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MSQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGGVSNNVFAYTLSISCNH
CADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLE
AIKFGPIDELRAKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRHA

Sequences:

>Translated_209_residues
MSQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGGVSNNVFAYTLSISCNH
CADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLE
AIKFGPIDELRAKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRHA
>Mature_208_residues
SQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPTGQGGVSNNVFAYTLSISCNHC
ADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEA
IKFGPIDELRAKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRHA

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=192, Percent_Identity=56.25, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1787872, Length=192, Percent_Identity=54.6875, Blast_Score=215, Evalue=1e-57,
Organism=Escherichia coli, GI1787749, Length=165, Percent_Identity=36.3636363636364, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790326, Length=167, Percent_Identity=34.1317365269461, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI1789370, Length=184, Percent_Identity=35.3260869565217, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI226510944, Length=151, Percent_Identity=39.7350993377483, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI2367345, Length=161, Percent_Identity=34.1614906832298, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787478, Length=155, Percent_Identity=30.3225806451613, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787740, Length=94, Percent_Identity=40.4255319148936, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787963, Length=145, Percent_Identity=30.3448275862069, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI87082179, Length=159, Percent_Identity=27.0440251572327, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87082180, Length=149, Percent_Identity=28.1879194630872, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367245, Length=165, Percent_Identity=25.4545454545455, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788811, Length=155, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22534; Mature: 22403

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
10.0 %Cys+Met (Translated Protein)
8.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPT
CCCCCCCCCCCCCCEEEEEECCCCCCCHHHHEEECCCCCHHHHHHHHHHHHCCCCEECCC
GQGGVSNNVFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWS
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCCCCCCCCEECC
CPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAKYGSVCDV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHHHHCCEEEC
NGLPDSSITKPNLVVKAHQGAEKEGKRHA
CCCCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVKGGSFIPT
CCCCCCCCCCCCCEEEEEECCCCCCCHHHHEEECCCCCHHHHHHHHHHHHCCCCEECCC
GQGGVSNNVFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDGIVRVDTDKCVGCGYCAWS
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCCCCCCCCEECC
CPYGAPQLNEQTGQMSKCDMCVDLLAKGEPPVCVATCPLEAIKFGPIDELRAKYGSVCDV
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCHHHHHHHHCCEEEC
NGLPDSSITKPNLVVKAHQGAEKEGKRHA
CCCCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]