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The map label for this gene is eutE [H]

Identifier: 16765783

GI number: 16765783

Start: 2573397

End: 2574800

Strand: Reverse

Name: eutE [H]

Synonym: STM2463

Alternate gene names: 16765783

Gene position: 2574800-2573397 (Counterclockwise)

Preceding gene: 16765784

Following gene: 16765782

Centisome position: 53.01

GC content: 59.9

Gene sequence:

>1404_bases
ATGAATCAACAGGATATTGAACAGGTGGTGAAAGCGGTACTGCTGAAAATGAAAGACAGCAGCCAGCCGGCCAGTACTGT
TCATGAGATGGGCGTTTTTGCCTCCCTGGATGACGCAGTGGCGGCAGCAAAACGGGCCCAGCAGGGGCTGAAGAGCGTGG
CGATGCGCCAGCTTGCCATTCATGCCATTCGCGAAGCGGGCGAAAAACACGCCCGAGAATTAGCGGAACTTGCCGTCAGC
GAAACCGGCATGGGACGCGTTGACGATAAATTTGCCAAAAACGTGGCGCAGGCGCGCGGCACGCCGGGCGTCGAGTGTTT
ATCTCCGCAGGTGCTGACCGGCGATAACGGCCTGACGCTGATTGAAAATGCACCGTGGGGCGTGGTGGCCTCGGTCACGC
CGTCCACCAATCCGGCGGCGACGGTGATTAATAACGCCATCAGCCTGATTGCCGCAGGCAACAGCGTCGTGTTTGCCCCG
CATCCGGCGGCGAAAAAGGTCTCTCAGCGGGCAATCACTCTCCTCAATCAGGCGGTGGTCGCCGCCGGTGGTCCGGAAAA
TTTGCTGGTCACCGTGGCGAACCCGGATATCGAAACCGCCCAGCGGTTGTTCAAATATCCCGGTATTGGCCTGCTGGTGG
TGACTGGCGGCGAAGCGGTGGTGGACGCGGCGCGTAAACATACTAATAAACGCCTGATCGCCGCCGGTGCCGGCAATCCC
CCGGTGGTGGTGGATGAGACCGCCGACCTGCCGCGCGCTGCACAATCCATCGTCAAAGGCGCGTCGTTTGATAACAACAT
CATCTGTGCCGACGAAAAAGTGCTGATTGTGGTGGATAGCGTCGCCGACGAGCTGATGCGTCTGATGGAAGGTCAGCACG
CGGTGAAACTGACCGCCGCTCAGGCCGAACAGCTCCAGCCGGTGCTGCTGAAGAATATCGATGAACGCGGCAAAGGCACC
GTCAGCCGTGACTGGGTCGGTCGTGACGCGGGCAAGATCGCCGCAGCCATCGGCCTGAACGTCCCGGATCAAACGCGCCT
GCTGTTTGTGGAAACGCCCGCCAACCATCCGTTTGCCGTTACTGAAATGATGATGCCGGTACTGCCGGTGGTGCGGGTCG
CCAACGTCGAAGAAGCCATCGCCCTGGCGGTTCAGCTTGAAGGCGGTTGCCACCATACGGCGGCGATGCACTCGCGCAAT
ATCGACAACATGAACCAGATGGCGAACGCCATCGACACCAGCATTTTCGTCAAAAACGGGCCGTGCATTGCCGGGCTTGG
ATTGGGCGGAGAAGGCTGGACCACCATGACTATCACTACGCCAACCGGCGAAGGGGTGACCAGCGCGCGTACCTTTGTGC
GGCTGCGTCGATGCGTGCTGGTGGATGCGTTTCGCATTGTATAA

Upstream 100 bases:

>100_bases
ATCGCAGCGAATTATCACCGGTCGATCTGTGCGTCATTGGCATCGTCGATGAAGTGGTGGCTGGCGGGAAAGTGGTTTTC
CATAAATAGGATTGAACATC

Downstream 100 bases:

>100_bases
GGGATGACTCATGGCGCACGACGAACAACTCTGGCTCACCCCAAGACTGCAAAAAGCGGCGGCCCTGTGTAACCAGACGC
CCGCCGCCAGCGATACACCG

Product: aldehyde oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVS
ETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAP
HPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNP
PVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGT
VSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRN
IDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV

Sequences:

>Translated_467_residues
MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVS
ETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAP
HPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNP
PVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGT
VSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRN
IDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
>Mature_467_residues
MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVS
ETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAP
HPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNP
PVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGT
VSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRN
IDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV

Specific function: May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI153266822, Length=310, Percent_Identity=23.2258064516129, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788797, Length=467, Percent_Identity=94.0042826552463, Blast_Score=847, Evalue=0.0,
Organism=Escherichia coli, GI1787493, Length=385, Percent_Identity=34.2857142857143, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1787558, Length=414, Percent_Identity=26.0869565217391, Blast_Score=88, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323821, Length=317, Percent_Identity=23.0283911671924, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012408
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: NA

Molecular weight: Translated: 49174; Mature: 49174

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAIREAGEKHARELAELAVSETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHCCCEEEECCCCEEE
IENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAPHPAAKKVSQRAITLLNQAVV
EECCCCCEEEECCCCCCCHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHHHHHHHHHH
AAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNP
CCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCC
PVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAA
CEEEECCCCCHHHHHHHHCCCCCCCCEEECCCEEEEEEHHHHHHHHHHHCCCCEEEEEHH
QAEQLQPVLLKNIDERGKGTVSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAV
HHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHH
TEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRNIDNMNQMANAIDTSIFVKNG
HHHHHHHHHHHHHCCHHHEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCEEEEECC
PCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
CEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDAVAAAKRAQQGLKSVAMRQLAI
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAIREAGEKHARELAELAVSETGMGRVDDKFAKNVAQARGTPGVECLSPQVLTGDNGLTL
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHCCCEEEECCCCEEE
IENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAPHPAAKKVSQRAITLLNQAVV
EECCCCCEEEECCCCCCCHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHHHHHHHHHH
AAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGEAVVDAARKHTNKRLIAAGAGNP
CCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCC
PVVVDETADLPRAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAA
CEEEECCCCCHHHHHHHHCCCCCCCCEEECCCEEEEEEHHHHHHHHHHHCCCCEEEEEHH
QAEQLQPVLLKNIDERGKGTVSRDWVGRDAGKIAAAIGLNVPDQTRLLFVETPANHPFAV
HHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCEEEEEECCCCCCHHH
TEMMMPVLPVVRVANVEEAIALAVQLEGGCHHTAAMHSRNIDNMNQMANAIDTSIFVKNG
HHHHHHHHHHHHHCCHHHEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHCCEEEEECC
PCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
CEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]