| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
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The map label for this gene is lysA [H]
Identifier: 16765687
GI number: 16765687
Start: 2471265
End: 2472662
Strand: Reverse
Name: lysA [H]
Synonym: STM2360
Alternate gene names: 16765687
Gene position: 2472662-2471265 (Counterclockwise)
Preceding gene: 16765689
Following gene: 16765686
Centisome position: 50.9
GC content: 49.79
Gene sequence:
>1398_bases ATGACTGACTCGATTATGCAGAATTACAACCAGCTACGTGAGCAGGTAATCAACGGCGATCGCCGTTTCCAGCACAAAGA CGGTCATTTGTGTTTTGAAGGGGTCGATCTGGACGCTCTGGCGCGCCAGTACCCCACGCCGTTCTATGTGTTTTCTGAGC CGGAGATTATTCGTAACATTCATGAAATCCAGCAGGCATTTGCGGCGCATAAAAATACCAAAACCTTCTTTGCGTCAAAA ACCTGCTCGGTCATGGGGGTGTTGAAAGCCATTCGTGACGCCGGAATTTGCGCGGAGGCAAACTCACAATATGAGGTTCG CAAGTGCCTGGAGATAGGCTTTCGCGGCGATCAGATCGTCTTCAACGGCGTGGTGAAAAAGCCTGCCGATCTGGAATATG CCATCGCCAACGATCTGTATCTTATTAATGTTGATAGCCTGTATGAGCTGGAACATATTGATGCCATCTCTCGCAAGCTG AAGAAAGTCGCCAATGTTTGCGTCCGCGTAGAACCGAATGTTCCCTCGGCGACGCATGCGGAACTGGTTACCGCTTTCCA TGCGAAGTCGGGTCTCGACCTGGAACAGGCGGAAGAAACCTGCCGCCGCATTCTGGCGATGCCTTATGTGCATTTGCGCG GCTTGCATATGCATGTGGGCGATCAGGTGCCGGAGTCAGAGCCTTTCGCAAAAGCGACTAAAGTGCTGGTGGATGAATCC CGTCGCCTGGAAGAGGTGCTTGGTATTAAATTTGATTTGATCAACGTGGGCGGCGGAATTCCGGTTCCCTATAAATATGA CGACGAGAATGGCGACCCGTTAAAAGATAATATGTATGCCGGTATTACCGCCCAGGATTTTGCCGATGCGGTCATTCGCG AAGTGCATAAATGGCGTACCGATGTGGAAATATGTATTGAACCGGGACGTAAAGTGACCGGGTCGGCGGCGGTTTTACTT ACGGAAGTCTCCTGCGAAAAACGTAAAACAAATTACGATCTTAACGGCAATGTGGAATGCCACGTTGAATGGAAATTTGT CGACGCTGGTTACAGCGTACTCTCTGACAGCCAGCATTTTGACTGGTTCTTTTATGTCTATAACGCCTCTCGCATGACGG CAGCGCACGACGCCTGGATAAAATTAGCCGGGCCGCTGTGTGATGGCGGAGATTATTTCCACATGGGAGTGAAAGGCGAA GAGTTTTTACTGCCGAAGGAGACTCATGTTGGCGATATTGTCGCATTTCTTGATGCCGGGGCATACACCATTGAAAGTCA AACCGTTTATAACAACCGTCCGCGCACGGGCGTGGTGATGATCGATAAAAATGGTGACACGCGTCTGATTCGTCGGGAAG ACAGTTACGAAGATATGGTCAAGTACGACATTTATTAA
Upstream 100 bases:
>100_bases ATAACTAATTGATTATTTTGATAAAAAATAGTGGCATGCCTTTTGCTTTATCCCTGTAAAGAATGCGGATTTTTACCATA AACATTAAGCAGAGGGCGTT
Downstream 100 bases:
>100_bases TACTGTTTTGGGCTTCAGTTTCATGCTGAAGCCCGTCGTCAGATGATAAGAAGAGGGCAGTGATGCCTGAATGCATAACA GGAGATGGCCATGAGTAACA
Product: diaminopimelate decarboxylase
Products: NA
Alternate protein names: DAP decarboxylase [H]
Number of amino acids: Translated: 465; Mature: 464
Protein sequence:
>465_residues MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASK TCSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKL KKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDES RRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLL TEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGE EFLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY
Sequences:
>Translated_465_residues MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASK TCSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKL KKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDES RRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLL TEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGE EFLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY >Mature_464_residues TDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASKT CSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKLK KVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDESR RLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLLT EVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGEE FLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY
Specific function: Lysine biosynthesis; last step. [C]
COG id: COG0019
COG function: function code E; Diaminopimelate decarboxylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]
Homologues:
Organism=Escherichia coli, GI1789203, Length=434, Percent_Identity=26.7281105990783, Blast_Score=104, Evalue=1e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009006 - InterPro: IPR002986 - InterPro: IPR022643 - InterPro: IPR022657 - InterPro: IPR022644 - InterPro: IPR022653 - InterPro: IPR000183 [H]
Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]
EC number: =4.1.1.20 [H]
Molecular weight: Translated: 52598; Mature: 52467
Theoretical pI: Translated: 5.25; Mature: 5.25
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNI CCCHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCHHHHHHHCCCCEEEECCCHHHHHH HEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIV HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCCCEEE FNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKLKKVANVCVRVEPNVPSATHA EECCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHH ELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDES HHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHH RRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRT HHHHHHHCCEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC DVEICIEPGRKVTGSAAVLLTEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHF CEEEEECCCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEEEEEECCHHHHCCCCCC DWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGEEFLLPKETHVGDIVAFLDAG EEEEEEEECCCCCCHHHCEEEEECCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHCCC AYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY CEEEECCEEECCCCCEEEEEEECCCCEEEEECCCCHHHHHEECCC >Mature Secondary Structure TDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNI CCHHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCHHHHHHHCCCCEEEECCCHHHHHH HEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIV HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCCCCCEEE FNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKLKKVANVCVRVEPNVPSATHA EECCCCCCCCCEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHH ELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDES HHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCCHHHHHHHHHHHH RRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRT HHHHHHHCCEEEEEECCCCCCCCEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCC DVEICIEPGRKVTGSAAVLLTEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHF CEEEEECCCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEEEEEECCHHHHCCCCCC DWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGEEFLLPKETHVGDIVAFLDAG EEEEEEEECCCCCCHHHCEEEEECCCCCCCCEEEECCCCCEEECCCCCCHHHHHHHHCCC AYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY CEEEECCEEECCCCCEEEEEEECCCCEEEEECCCCHHHHHEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]