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The map label for this gene is ccmE [H]

Identifier: 16765578

GI number: 16765578

Start: 2350915

End: 2351394

Strand: Reverse

Name: ccmE [H]

Synonym: STM2250

Alternate gene names: 16765578

Gene position: 2351394-2350915 (Counterclockwise)

Preceding gene: 16765579

Following gene: 16765577

Centisome position: 48.41

GC content: 65.42

Gene sequence:

>480_bases
GTGAACCTGCGACGTAAAAACCGGCTATGGGTGGTCTGCGCGGTGCTGGCGGGCCTGGGGCTGACCACCGCCCTGGTCCT
GTACGCGCTGCGCGCGAATATCGACCTGTTCTATACCCCCGGCGAAATCCTCTACGGCAAGCGCGAGACGCAGCAGCTGC
CGGCGGCGGGCCAGCGCCTGCGCGTCGGCGGGATGGTGATGCCCGGCAGTGTCAGGCGCGACCCGGACTCGCTGAAGGTG
AACTTCAGTCTCTACGACGCCGAAGGGTCGGTGACGGTGAGCTATGAGGGGATACTGCCGGACCTGTTCCGCGAGGGGCA
GGGGGTGGTGGTGCAGGGCACCCTGGAGAAGGGCAACCACGTCCTGGCGCACGAGGTGCTGGCCAAACATGACGAGAACT
ACACCCCGCCGGAAGTGGAAAAGGCGATGCAGGAAAACCACCGCCGCCCGCAACGCGCTGATAAGGACACCTCATCATGA

Upstream 100 bases:

>100_bases
TGCACACGGTGCTGCAGCGCCGGGCCATTCTGCGCGGCGTGGCGCAGCAGCGGGCGCGCGAGGCGCGGATGCGTGCCGCA
CAGGCGCAACAGGAGGCCGC

Downstream 100 bases:

>100_bases
TGCCTGAATACGGCCACGCGCTGCTGTGCCTGGCGCTCGGCGTGGCGCTGCTGCTGTCCGTTTACCCGCTGTGGGGCGTG
GCGCGCGGTGACGCGCGGAT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1 [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRDPDSLKV
NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS

Sequences:

>Translated_159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRDPDSLKV
NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
>Mature_159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRDPDSLKV
NFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=159, Percent_Identity=83.0188679245283, Blast_Score=281, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 17688; Mature: 17688

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRL
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCHHEECCCHHHHCCCCCCEE
RVGGMVMPGSVRRDPDSLKVNFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNH
EECCEECCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHCCCCEEEEEECCCCCC
VLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRL
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCHHEECCCHHHHCCCCCCEE
RVGGMVMPGSVRRDPDSLKVNFSLYDAEGSVTVSYEGILPDLFREGQGVVVQGTLEKGNH
EECCEECCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCHHHHHCCCCEEEEEECCCCCC
VLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA