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The map label for this gene is rtn [H]

Identifier: 16765544

GI number: 16765544

Start: 2314556

End: 2316112

Strand: Direct

Name: rtn [H]

Synonym: STM2215

Alternate gene names: 16765544

Gene position: 2314556-2316112 (Clockwise)

Preceding gene: 16765543

Following gene: 16765545

Centisome position: 47.65

GC content: 51.89

Gene sequence:

>1557_bases
ATGCTAACACGCGACTCCTCTTCCGGTCGGAAAATCCTGCTTACCTGTATCATTACGGGGATAGCGGCAGCATTACTTAT
TGGTAGCCTGCAATTTTTCCTGTCGTGGCATAAACGGGATGTTAAATACAATACGCTCCTTTCTGATGTACAACATTACC
TGGCCAGCTATTTCGCCGACCTGAAAGCCACCACCGATATTCTTCAACCGTTGACGATCAACACCTGTCAGCAGGTTGGC
GCAGAACTCACCTCAAGAGCCGCTTTTAGCCTTAATGTCCGCGCCTTCTTATTGATTAAAGATAAAAAAGTGTTCTGCTC
TTCCGCCACTGGCGCCATGAATATGCCGCTTCAGCAACTGGTACCGGATATAGATATCCGCAAAGACGTTGCTATGGCGA
TTCTGCCCGGCACGCCAATGATGCCCAACAAACCGACAATGGTGATTTGGTATCGAAACCCATTATTAAATGACAGCGGC
GTATTCACATCGCTGAATATTAACCTGACGCCCTACTTACTCTATACCACGCGCCAGGATGATTTTAACGGCATCGCGCT
GATTGTCGGCAATACCGCTCTGTCGACCTTTTCTTCGCGTCTACTGACCGTCGCGGAGCTGCCGGGCACGCCATCACGAC
TGGCAACTATCAACGGCCTGCCGCTTAAAATACGGCTTTATGCCGATAGCTGGACCTACAATGACTTGTGGTATGCGTTG
ATGCTGGGCTGCATTAGCGGCATCGTAGCAGGGTTTATCTGTTACTTTATCTATGCCCTCCGGACGCGACCGGGCAAAGA
GATTTTAACGGCGATCAAACACGAGCAGTTTTATGTGGTTTATCAGCCCGTCGTCGATACTCGTACGCTGAGCGTCACCG
GGCTTGAAGTCTTACTGCGCTGGCGTCACCCTACGGCAGGCGAGATTCCGCCGGATGCCTTTATCCACTATGCCGAAGCG
CAGCAACTTATCGTACCGTTAACGCAGCATCTGTTCGAGCTGATCGCCCGCGACGCACCCACGCTACAGAAGGTGATGCC
CGTCGGTGCCAAATTTGGCATTAACATCGCGCCGGAACATCTGCACAGCGACAGTTTTAAAGAGGATATGCACCGGCTCA
GGGACGCCCTGCCCGCGCACCATTTTCATATCGTGCTGGAAATCACTGAACGCGATATGCTCCAGCAGTATGAAGCGGCC
AAACTGTTCGAATGGCTGCATTCCGCCGGGTTTGAAATCGCTATAGATGATTTCGGTACAGGCCATAGCGCCCTGATTTA
TCTGGAGCGATTTACTTTAGATTATCTGAAAATCGATCGCGGCTTTATCCAGGCGATCGGCACGGAAACCGTCACGTCTC
CGGTTCTGGATACCGTGCTGACGCTCTCCAGACGCCTGAATATGCTGACGGTGGCCGAGGGCGTTGAAACGCCGGAGCAG
GCCCGTTGGCTACGCGATCACGGTGTTAATTACTTGCAGGGGTACTGGATTAGTCGTCCTTTACCCCTAAAAGATTTCGT
GCTGTGGATGTCGGCGCCTTCTGTGCCTGAATGGTAG

Upstream 100 bases:

>100_bases
GCATCACAGAAAAGCATGACTATCCGGGGTAATCCAGGCTATAGTCTTATAAATCAACCAGTTTAACCGGCATCCGCCTT
TTCAGGTCACACCAGGAATT

Downstream 100 bases:

>100_bases
CCCCCTTACGGTTTTAACGGATTCACATCAGACGCAACGTCACTTATTATTCAGCGAAACGCCTGCCGGTTTGCAGCGGG
CAATACGATAAGGAAACCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYNTLLSDVQHYLASYFADLKATTDILQPLTINTCQQVG
AELTSRAAFSLNVRAFLLIKDKKVFCSSATGAMNMPLQQLVPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNDSG
VFTSLNINLTPYLLYTTRQDDFNGIALIVGNTALSTFSSRLLTVAELPGTPSRLATINGLPLKIRLYADSWTYNDLWYAL
MLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQFYVVYQPVVDTRTLSVTGLEVLLRWRHPTAGEIPPDAFIHYAEA
QQLIVPLTQHLFELIARDAPTLQKVMPVGAKFGINIAPEHLHSDSFKEDMHRLRDALPAHHFHIVLEITERDMLQQYEAA
KLFEWLHSAGFEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDTVLTLSRRLNMLTVAEGVETPEQ
ARWLRDHGVNYLQGYWISRPLPLKDFVLWMSAPSVPEW

Sequences:

>Translated_518_residues
MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYNTLLSDVQHYLASYFADLKATTDILQPLTINTCQQVG
AELTSRAAFSLNVRAFLLIKDKKVFCSSATGAMNMPLQQLVPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNDSG
VFTSLNINLTPYLLYTTRQDDFNGIALIVGNTALSTFSSRLLTVAELPGTPSRLATINGLPLKIRLYADSWTYNDLWYAL
MLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQFYVVYQPVVDTRTLSVTGLEVLLRWRHPTAGEIPPDAFIHYAEA
QQLIVPLTQHLFELIARDAPTLQKVMPVGAKFGINIAPEHLHSDSFKEDMHRLRDALPAHHFHIVLEITERDMLQQYEAA
KLFEWLHSAGFEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDTVLTLSRRLNMLTVAEGVETPEQ
ARWLRDHGVNYLQGYWISRPLPLKDFVLWMSAPSVPEW
>Mature_518_residues
MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYNTLLSDVQHYLASYFADLKATTDILQPLTINTCQQVG
AELTSRAAFSLNVRAFLLIKDKKVFCSSATGAMNMPLQQLVPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNDSG
VFTSLNINLTPYLLYTTRQDDFNGIALIVGNTALSTFSSRLLTVAELPGTPSRLATINGLPLKIRLYADSWTYNDLWYAL
MLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQFYVVYQPVVDTRTLSVTGLEVLLRWRHPTAGEIPPDAFIHYAEA
QQLIVPLTQHLFELIARDAPTLQKVMPVGAKFGINIAPEHLHSDSFKEDMHRLRDALPAHHFHIVLEITERDMLQQYEAA
KLFEWLHSAGFEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDTVLTLSRRLNMLTVAEGVETPEQ
ARWLRDHGVNYLQGYWISRPLPLKDFVLWMSAPSVPEW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=70.4633204633205, Blast_Score=803, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=523, Percent_Identity=30.019120458891, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI87081845, Length=446, Percent_Identity=30.2690582959641, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1786507, Length=241, Percent_Identity=36.5145228215768, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87081743, Length=270, Percent_Identity=32.5925925925926, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790496, Length=281, Percent_Identity=29.8932384341637, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1787541, Length=344, Percent_Identity=27.6162790697674, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081921, Length=249, Percent_Identity=30.9236947791165, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788849, Length=240, Percent_Identity=28.75, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI226510982, Length=244, Percent_Identity=29.9180327868852, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI87082096, Length=249, Percent_Identity=31.7269076305221, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787055, Length=243, Percent_Identity=29.6296296296296, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787410, Length=113, Percent_Identity=30.9734513274336, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58372; Mature: 58372

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYNTLLSDVQHYLASYFAD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKATTDILQPLTINTCQQVGAELTSRAAFSLNVRAFLLIKDKKVFCSSATGAMNMPLQQL
HHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECEEEEEEEECCEEEECCCCCCCCCCHHHH
VPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNDSGVFTSLNINLTPYLLYTTRQD
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCC
DFNGIALIVGNTALSTFSSRLLTVAELPGTPSRLATINGLPLKIRLYADSWTYNDLWYAL
CCCCEEEEECCHHHHHHHHHHEEEEECCCCCHHEEEECCCEEEEEEEECCCCCHHHHHHH
MLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQFYVVYQPVVDTRTLSVTGLEVLLR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHEE
WRHPTAGEIPPDAFIHYAEAQQLIVPLTQHLFELIARDAPTLQKVMPVGAKFGINIAPEH
ECCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHH
LHSDSFKEDMHRLRDALPAHHFHIVLEITERDMLQQYEAAKLFEWLHSAGFEIAIDDFGT
HCCCHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDTVLTLSRRLNMLTVAEGVETPEQ
CCEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHH
ARWLRDHGVNYLQGYWISRPLPLKDFVLWMSAPSVPEW
HHHHHHCCCCHHCCEECCCCCCHHHHHEEECCCCCCCC
>Mature Secondary Structure
MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYNTLLSDVQHYLASYFAD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LKATTDILQPLTINTCQQVGAELTSRAAFSLNVRAFLLIKDKKVFCSSATGAMNMPLQQL
HHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECEEEEEEEECCEEEECCCCCCCCCCHHHH
VPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNDSGVFTSLNINLTPYLLYTTRQD
CCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCC
DFNGIALIVGNTALSTFSSRLLTVAELPGTPSRLATINGLPLKIRLYADSWTYNDLWYAL
CCCCEEEEECCHHHHHHHHHHEEEEECCCCCHHEEEECCCEEEEEEEECCCCCHHHHHHH
MLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQFYVVYQPVVDTRTLSVTGLEVLLR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHEE
WRHPTAGEIPPDAFIHYAEAQQLIVPLTQHLFELIARDAPTLQKVMPVGAKFGINIAPEH
ECCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHH
LHSDSFKEDMHRLRDALPAHHFHIVLEITERDMLQQYEAAKLFEWLHSAGFEIAIDDFGT
HCCCHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFIQAIGTETVTSPVLDTVLTLSRRLNMLTVAEGVETPEQ
CCEEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHH
ARWLRDHGVNYLQGYWISRPLPLKDFVLWMSAPSVPEW
HHHHHHCCCCHHCCEECCCCCCHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]