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The map label for this gene is pbpG [H]

Identifier: 16765498

GI number: 16765498

Start: 2265525

End: 2266472

Strand: Reverse

Name: pbpG [H]

Synonym: STM2168

Alternate gene names: 16765498

Gene position: 2266472-2265525 (Counterclockwise)

Preceding gene: 16765499

Following gene: 16765496

Centisome position: 46.66

GC content: 53.9

Gene sequence:

>948_bases
ATGCTGAAATTCCGAGCTTCATTCCTGAGCCTTGCTCTGATGTTGGCCGTACCTTTTGCCCCGCAGGCTGTGGCGAAAAC
GGCAGCGACAACCGCGGCGTCTCAACCTGAGATTGCCTCCGGTAGCGCAATGATTGTTGATCTCAACACCAATAAAGTGA
TCTATTCGAACCACCCGGATCTGGTGCGTCCGATTGCCTCGATAACCAAATTAATGACAGCGATGGTCGTGCTCGACGCG
CGATTGCCGCTGGATGAAATACTGAAGGTCGATATCAGCCAGACGCCGGAAATGAAAGGGGTTTACTCCCGCGTGCGCCT
GAACAGCGAAATTAGCCGCAAAAATATGTTGCTGCTGGCGTTGATGTCATCCGAAAACCGTGCGGCGGCAAGCCTGGCGC
ACTATTATCCTGGCGGTTATAACGCATTTATTAAAGCGATGAATGCGAAGGCGAAAGCGCTGGGCATGACGCATACCCGC
TTCGTTGAGCCTACGGGGCTGTCGATTCATAACGTCTCGACCGCGCGGGATTTAACAAAATTGCTGATTGCCACGAAGCA
ATACCCGCTGATTGGCCAGCTAAGCACCACGCGCGAAGACATGGCGACATTCTCGCATCCGGCGTATACGCTGCCGTTTC
GCAATACCAACCATTTGGTCTACCGTGATAACTGGAATATCCAGTTAACGAAAACCGGATTTACCAATGCGGCGGGGCAT
TGCCTGGTGATGCGTACCGTGATCAATAACAAACCGGTCGCGCTGGTGGTCATGGACGCGTTCGGCAAATATACCCACTT
TGCGGACGCCAGCCGCCTGCGTACATGGATTGAAACCGGTAAAGTCATGCCCGTTCCGGCTGCCGCGCTGAGCTATAAAA
AGCAAAAAGCCGCGCAAATGGCGGCAGCCAGCGCCAGTGCCGGAGCGCAAACCGCACAGAACGATTAA

Upstream 100 bases:

>100_bases
ACGCTGGCGTGCCGCTATGATGCCACTGCTAGCTTGAGTATAATCTTAGCTCAGGCGGTGTGCGTTACGACGCGCGTGAA
TCATTATCAGAAATCTCATC

Downstream 100 bases:

>100_bases
GTCGCCGCAGGCCCGGCAGGCATCGCGCCGCCGGGCTTCACGGTAAACCGCACGGTGTTAATGCGTTTCGTCGGGCGTAT
TTTCCTGCCAGAATTTCCGC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MLKFRASFLSLALMLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDA
RLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTR
FVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
CLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND

Sequences:

>Translated_315_residues
MLKFRASFLSLALMLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDA
RLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTR
FVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
CLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND
>Mature_315_residues
MLKFRASFLSLALMLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASITKLMTAMVVLDA
RLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTR
FVEPTGLSIHNVSTARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
CLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAASASAGAQTAQND

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=292, Percent_Identity=93.8356164383562, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1787062, Length=269, Percent_Identity=28.6245353159851, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082022, Length=273, Percent_Identity=27.1062271062271, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786851, Length=287, Percent_Identity=25.7839721254355, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 34288; Mature: 34288

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFRASFLSLALMLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPD
CCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCH
LVRPIASITKLMTAMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCHHCCCCEEEEE
LMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVSTARDLTK
EECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHH
LLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
HHHHHCCCCCEECCCCCHHHHHHHCCCCEEECCCCCCEEEEECCCEEEEEECCCCCCCCC
CLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQM
EEEEEEHHCCCCEEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAASASAGAQTAQND
HHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKFRASFLSLALMLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSNHPD
CCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEECCCCH
LVRPIASITKLMTAMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKNMLLLA
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCHHCCCCEEEEE
LMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVSTARDLTK
EECCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCHHEEECCCCCEEECCHHHHHHHH
LLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTKTGFTNAAGH
HHHHHCCCCCEECCCCCHHHHHHHCCCCEEECCCCCCEEEEECCCEEEEEECCCCCCCCC
CLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQM
EEEEEEHHCCCCEEEEEEECCCCHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AAASASAGAQTAQND
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]