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The map label for this gene is yehW [H]

Identifier: 16765492

GI number: 16765492

Start: 2257247

End: 2257978

Strand: Reverse

Name: yehW [H]

Synonym: STM2162

Alternate gene names: 16765492

Gene position: 2257978-2257247 (Counterclockwise)

Preceding gene: 16765493

Following gene: 16765489

Centisome position: 46.49

GC content: 59.56

Gene sequence:

>732_bases
GTGAAACGACTGTGTGATCCGCTTCTCTGGCTTATTGTTCTGTTCTTGCTTCTGCTGTTTGGATTGCCTTATAGCCAGCC
GTTCTTCGCCGCGCTGTTTCCCGATTTACCGCGCCCGGTCTACCAACAGGAGAGTTTTGCCGCCCTCGCGCTCGCCCATT
TCTGGTTGGTGGGCATCTCAAGTTTGTTTGCCGTCGTGGTGGGCGTCGGCGCAGGGATTGCGGTCACGCGAGAAAGTGGG
AAAGAGTTTCGTCCCCTGGTGGAGACTATCGCCGCCGTCGGGCAGACCTTTCCCCCGGTCGCGGTACTGGCGATCGCGGT
ACCCGTCATGGGTTTTGGTCAGCAACCGGCCATTATCGCCTTGATCCTGTATGGGGTGTTGCCCATCCTGCAGGCGACCC
TGGCCGGGCTGGGCGCGGTGCCTGCCAGCGTGATGAGCGTTGCCAGCGGTATGGGAATGAGCCGTCGCCAACAGTTGTAT
CAGGTTGAGCTGCCGCTGGCCGCGCCGGTGATTCTGGCGGGCATCCGAACCTCGGTGATTATCAATATTGGTACGGCGAC
CATCGCTTCAACGGTGGGGGCCAGTACGTTAGGCACGCCGATCATTATCGGGCTTAGCGGCTTTAATACGGCCTATGTTA
TCCAGGGGGCGCTGCTGGTGGCGCTGGCGGCGATCATTATCGATCGCCTGTTTGAAAGGCTGACGCGCGTGCTTACCCGG
CACGCAAAATAA

Upstream 100 bases:

>100_bases
TTTGTCGCCCGTCGGTGCGACGTCCTGCCGGTGGCGAATCAGCAGGGCGAGCCCTGCGGTACGCTCCATTTCCGCGATCT
GCTTTCGGAGACGTCCCCCC

Downstream 100 bases:

>100_bases
AACTGTAACCTGCCAGCATCACGCCGCCGATACCGCCAATAGCCATCAGCAGGAAAAGGGCGATCACCCCGATTTTCGCT
ACGCGCATTATGTACTCCTT

Product: ABC-type proline/glycine betaine transport system permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQESFAALALAHFWLVGISSLFAVVVGVGAGIAVTRESG
KEFRPLVETIAAVGQTFPPVAVLAIAVPVMGFGQQPAIIALILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLY
QVELPLAAPVILAGIRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIIDRLFERLTRVLTR
HAK

Sequences:

>Translated_243_residues
MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQESFAALALAHFWLVGISSLFAVVVGVGAGIAVTRESG
KEFRPLVETIAAVGQTFPPVAVLAIAVPVMGFGQQPAIIALILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLY
QVELPLAAPVILAGIRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIIDRLFERLTRVLTR
HAK
>Mature_243_residues
MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQESFAALALAHFWLVGISSLFAVVVGVGAGIAVTRESG
KEFRPLVETIAAVGQTFPPVAVLAIAVPVMGFGQQPAIIALILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLY
QVELPLAAPVILAGIRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIIDRLFERLTRVLTR
HAK

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=243, Percent_Identity=85.1851851851852, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1788451, Length=212, Percent_Identity=33.4905660377358, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789033, Length=176, Percent_Identity=30.6818181818182, Blast_Score=87, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25599; Mature: 25599

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQESFAALALAHFWLVGIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLFAVVVGVGAGIAVTRESGKEFRPLVETIAAVGQTFPPVAVLAIAVPVMGFGQQPAIIA
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
LILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLYQVELPLAAPVILAGIRTSVI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHE
INIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIIDRLFERLTRVLTR
EECCHHHHHHHHCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAK
CCC
>Mature Secondary Structure
MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQESFAALALAHFWLVGIS
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLFAVVVGVGAGIAVTRESGKEFRPLVETIAAVGQTFPPVAVLAIAVPVMGFGQQPAIIA
HHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
LILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLYQVELPLAAPVILAGIRTSVI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHE
INIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIIDRLFERLTRVLTR
EECCHHHHHHHHCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]