| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
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The map label for this gene is sopA [H]
Identifier: 16765396
GI number: 16765396
Start: 2141570
End: 2143918
Strand: Direct
Name: sopA [H]
Synonym: STM2066
Alternate gene names: 16765396
Gene position: 2141570-2143918 (Clockwise)
Preceding gene: 16765388
Following gene: 16765397
Centisome position: 44.09
GC content: 47.42
Gene sequence:
>2349_bases ATGAAGATATCATCAGGCGCAATTAATTTTTCTACTATTCCTAACCAGGTTAAAAAATTAATTACCTCTATTCGTGAACA TACGAAAAACGGGCTCACCTCAAAAATAACCAGTGTTAAAAACACGCATACATCTTTAAATGAAAAATTTAAAACAGGAA AGGACTCACCGATTGAGTTCGCGTTACCACAAAAAATAAAAGACTTCTTTCAGCCGAAAGATAAAAACACCTTAAACAAA ACATTGATTACTGTTAAAAATATTAAAGATACAAATAATGCAGGCAAGAAAAATATTTCAGCAGAAGATGTCTCAAAAAT GAATGCAGCATTCATGCGTAAGCATATTGCAAATCAAACATGTGATTATAATTACAGAATGACAGGTGCGGCCCCGCTCC CCGGTGGAGTCTCTGTATCAGCCAATAACAGGCCCACGGTTTCTGAAGGTAGAACACCACCAGTATCCCCCTCCCTCTCA CTTCAGGCTACCTCTTCCCCGTCATCACCTGCCGACTGGGCTAAGAAACTCACGGATGCAGTTTTACGACAGAAAGCCGG AGAAACCCTTACGGCCGCAGATCGCGATTTTTCAAACGCAGATTTCCGTAATATTACATTCAGCAAAATATTGCCCCCCA GCTTCATGGAGCGAGACGGCGATATTATTAAGGGGTTCAACTTTTCAAATTCAAAATTTACTTATTCTGATATATCTCAT TTACATTTTGACGAATGCCGATTCACTTATTCGACACTGAGTGATGTAGTCTGCAGTAATACGAAATTTAGTAATTCAGA CATGAATGAAGTGTTTTTACAGTATTCAATTACTACACAACAACAGCCCTCGTTTATTGATACAACATTAAAAAATACGC TTATACGTCACAAAGCCAACCTCTCTGGCGTTATTTTAAATGAACCGGATAATTCATCACCTCCGTCAGTGTCAGGGGGC GGAAATTTTATTCGTCTAGGTGATATCTGGCTGCAAATGCCACTCCTTTGGACTGAGAACGCTGTGGATGGATTTTTAAA TCATGAGCACAATAATGGTAAAAGTATTCTGATGACCATTGACAGCCTGCCCGATAAATACAGTCAGGAAAAAGTCCAGG CAATGGAAGACCTGGTTAAGTCATTGCGGGGTGGCCGCTTAACAGAGGCATGTATCCGGCCAGTTGAAAGTTCGCTGGTA AGCGTACTGGCCCACCCCCCCTATACGCAAAGTGCGCTTATCAGCGAGTGGCTCGGGCCTGTTCAGGAACGTTTTTTTGC CCACCAGTGCCAGACCTATAATGACGTTCCCCTGCCGGCTCCTGACACATATTATCAGCAGCGCATACTGCCTGTGTTGC TGGATTCGTTTGACAGGAACAGCGCCGCCATGACCACTCACAGCGGACTCTTTAATCAGGTGATTTTACACTGTATGACA GGCGTGGACTGCACTGATGGCACCCGCCAGAAAGCTGCAGCGCTTTATGAACAGTATCTTGCTCACCCGGCGGTGTCTCC CCACATCCATAATGGGCTCTTCGGCAATTATGATGGCAGCCCGGACTGGACAACCCGCGCTGCAGATAATTTCCTGCTGC TTTCCTCCCAAGATTCAGACACGGCGATGATGCTCTCCACTGACACGCTGTTAACAATGCTAAACCCTACTCCTGACACT GCATGGGACAACTTTTACCTGCTGCGAGCCGGAGAGAACGTTTCCACCGCGCAAATCTCTCCGGTAGAGTTATTCCGTCA TGACTTTCCGGTGTTTCTCGCCGCATTTAATCAGCAGGCCACGCAGCGACGCTTTGGGGAGCTGATTGATATCATCCTCA GCACTGAAGAGCACGGGGAGCTGAACCAGCAGTTTCTTGCCGCCACGAACCAGAAACATTCCACCGTGAAGTTGATTGAT GATGCCTCAGTGTCGCGTCTGGCCACCATTTTTGACCCCTTGCTTCCTGAAGGCAAACTCAGCCCGGCACACTACCAGCA CATCCTCAGTGCTTATCACCTGACGGACGCCACCCCACAGAAGCAGGCGGAAACCCTGTTCTGTCTCAGTACCGCATTCG CACGCTATTCCTCCAGCGCCATTTTCGGCACTGAGCATGACTCTCCGCCGGCCCTGAGAGGCTATGCGGAGGCGCTGATG CAGAAAGCCTGGGAGCTGTCTCCGGCGATATTCCCATCCAGCGAACAGTTTACCGAGTGGTCCGACCGTTTTCACGGCCT CCATGGCGCCTTTACCTGTACCAGCGTTGTGGCGGATAGTATGCAACGTCATGCCAGAAAATATTTCCCGAGTGTTCTGT CATCCATCCTGCCACTGGCCTGGGCGTAG
Upstream 100 bases:
>100_bases TGAATTGTGATCTCCATCGCCATACCGACATATGAAGCTTACTTTTAAGGCGTTAAAAATCCAGACCGTTTTTCCATAAT GATGTTGATAAGGAATTCTA
Downstream 100 bases:
>100_bases TCCAGCCTCAACCCGCATGGAATTAAGGGACACAGCGTTGTGTCCCTCTGTACATAGACCCGTTTTAGTCCATGCATTTT TTGAGATCCCGGCCAGATTG
Product: secreted effector protein
Products: NA
Alternate protein names: Salmonella outer protein A; Secreted effector protein SopA [H]
Number of amino acids: Translated: 782; Mature: 782
Protein sequence:
>782_residues MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKANLSGVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLV SVLAHPPYTQSALISEWLGPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLID DASVSRLATIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA
Sequences:
>Translated_782_residues MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKANLSGVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLV SVLAHPPYTQSALISEWLGPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLID DASVSRLATIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA >Mature_782_residues MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEFALPQKIKDFFQPKDKNTLNK TLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQTCDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLS LQATSSPSSPADWAKKLTDAVLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISH LHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKANLSGVILNEPDNSSPPSVSGG GNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTIDSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLV SVLAHPPYTQSALISEWLGPVQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT GVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSDTAMMLSTDTLLTMLNPTPDT AWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQATQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLID DASVSRLATIFDPLLPEGKLSPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM QKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLAWA
Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway [H]
COG id: COG1357
COG function: function code S; Uncharacterized low-complexity proteins
Gene ontology:
Cell location: Secreted. Host cell (By similarity). Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell (By similarity) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the SopA E3 ligase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
NA
Pfam domain/function: NA
EC number: NA
Molecular weight: Translated: 86783; Mature: 86783
Theoretical pI: Translated: 6.75; Mature: 6.75
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEF CCCCCCCEEHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEE ALPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQT ECHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC CDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDA CCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH VLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISH HHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHCCCCEEECCCCCCCEEEHHHHCH LHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKAN HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC LSGVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTI CCEEEEECCCCCCCCCCCCCCCEEEECHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEEE DSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLVSVLAHPPYTQSALISEWLGP CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH VQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC GVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSD CCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC TAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQA CEEEEECCHHEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH TQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLIDDASVSRLATIFDPLLPEGKL HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC SPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH QKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLA HHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC WA CC >Mature Secondary Structure MKISSGAINFSTIPNQVKKLITSIREHTKNGLTSKITSVKNTHTSLNEKFKTGKDSPIEF CCCCCCCEEHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEE ALPQKIKDFFQPKDKNTLNKTLITVKNIKDTNNAGKKNISAEDVSKMNAAFMRKHIANQT ECHHHHHHHHCCCCCCCHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC CDYNYRMTGAAPLPGGVSVSANNRPTVSEGRTPPVSPSLSLQATSSPSSPADWAKKLTDA CCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH VLRQKAGETLTAADRDFSNADFRNITFSKILPPSFMERDGDIIKGFNFSNSKFTYSDISH HHHHHCCCEEECCCCCCCCCCCCCCCHHHCCCHHHHHCCCCEEECCCCCCCEEEHHHHCH LHFDECRFTYSTLSDVVCSNTKFSNSDMNEVFLQYSITTQQQPSFIDTTLKNTLIRHKAN HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCC LSGVILNEPDNSSPPSVSGGGNFIRLGDIWLQMPLLWTENAVDGFLNHEHNNGKSILMTI CCEEEEECCCCCCCCCCCCCCCEEEECHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEEE DSLPDKYSQEKVQAMEDLVKSLRGGRLTEACIRPVESSLVSVLAHPPYTQSALISEWLGP CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH VQERFFAHQCQTYNDVPLPAPDTYYQQRILPVLLDSFDRNSAAMTTHSGLFNQVILHCMT HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHC GVDCTDGTRQKAAALYEQYLAHPAVSPHIHNGLFGNYDGSPDWTTRAADNFLLLSSQDSD CCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCHHCCCCEEEEECCCCC TAMMLSTDTLLTMLNPTPDTAWDNFYLLRAGENVSTAQISPVELFRHDFPVFLAAFNQQA CEEEEECCHHEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH TQRRFGELIDIILSTEEHGELNQQFLAATNQKHSTVKLIDDASVSRLATIFDPLLPEGKL HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCC SPAHYQHILSAYHLTDATPQKQAETLFCLSTAFARYSSSAIFGTEHDSPPALRGYAEALM CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHH QKAWELSPAIFPSSEQFTEWSDRFHGLHGAFTCTSVVADSMQRHARKYFPSVLSSILPLA HHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC WA CC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA