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The map label for this gene is pocR

Identifier: 16765366

GI number: 16765366

Start: 2114399

End: 2115310

Strand: Reverse

Name: pocR

Synonym: STM2036

Alternate gene names: 16765366

Gene position: 2115310-2114399 (Counterclockwise)

Preceding gene: 16765367

Following gene: 16765365

Centisome position: 43.55

GC content: 45.94

Gene sequence:

>912_bases
ATGATTTCTGCGAGCGCTCTGAACTCAGAACTCATTAATAAAATCGCACAGGATTTTGCACAAGCCACCGGTCTGGCGGT
TGTGGTTGTCAATATTCATGGTGATGAAATATCTGAGCTATTCAATTTCACGCCGTTTTGTCAGTTGATGCGGCAGCATC
CCCAGCATAGTACACGTTGTCGTATGAGCGATCGCTGCGGGGGACTGGAGGCATCGAAGTCCGATCAACCCTGTATTTAT
CGTTGTCATGCCGGTCTAACGGATTTTTCTATTCCGCTGGTAATCGCAGGGCATTTAGTTGGCTTTGTTTTATGCGGGCA
GGTTCGTTTAAGTAATGACGTGGAGCTGGTAAACATTCTTAATGTTGACGATCGCTGGCAGGCTGACCCTGAGCTCTTGA
ATGAATTTCGGAATGTGCCAGAGATGGACTATTCACGCGTTATCGCTTCCGCCGATCTTCTTAAACTGATTGTTGAGAAT
TGCCTGAAAAAACAGCTCAATTTCGTGGTTATCAAAGACAATCCGCAGCAATCGGAGGCAAATAAAACCACTCGTGGTCC
CACTCCGCATGACAGTAAAATGAAAAAAGCGCTTCGCTATATTGATGCGCATTTGTCCGACGATCTTCGTCTTGAGGATG
TCGCCTCACATGTCTATCTCAGCCCCTATTACTTCAGTAAGCTATTCAAGAAATATCAGGGAATCGGATTTAATGCGTGG
GTAAACCGCCAGAGAATGGTTAGCGCCAGAGAATTGCTTTGCCATAGTGACTGGAGTATTGCCAGTATTGCGCGTAATTT
AGGCTTTTCGCAAACCAGCTATTTTTGCAAAGTCTTCCGCCAGACCTATCAGGTTACGCCGCAGGCTTATCGCCAGCAGA
TAAATGAGAATTCTCATCCTCCATCGTTATGA

Upstream 100 bases:

>100_bases
TGTCATTGTACTTTTTATCAGGGCCAGGATAATGGTAATAAAAAGTGAATGTAAATAATGTGTTTTGTTTATAACAATAA
ATTAACTGAGGGGTTTTATC

Downstream 100 bases:

>100_bases
ATAGCAATATTTTGCTATTGCCGATTTTTGATAGTCTTTTGTATCTTAATCATTTCAGAAAGAAAATTTATCTGGTGTAA
CAATAAATTGTCATAGCGCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVEN
CLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAW
VNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSL

Sequences:

>Translated_303_residues
MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVEN
CLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAW
VNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSL
>Mature_303_residues
MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCIY
RCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVEN
CLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAW
VNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHPPSL

Specific function: Positive regulatory protein of pdu and cob operons

COG id: COG4936

COG function: function code TK; Predicted sensor domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790391, Length=99, Percent_Identity=39.3939393939394, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786251, Length=109, Percent_Identity=35.7798165137615, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790339, Length=101, Percent_Identity=30.6930693069307, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): POCR_SALTY (Q05587)

Other databases:

- EMBL:   AF026270
- EMBL:   AE006468
- EMBL:   L12006
- RefSeq:   NP_460981.1
- ProteinModelPortal:   Q05587
- SMR:   Q05587
- PRIDE:   Q05587
- GeneID:   1253557
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2036
- NMPDR:   fig|99287.1.peg.1961
- HOGENOM:   HBG417292
- OMA:   VNQQRMA
- ProtClustDB:   CLSK894248
- BioCyc:   STYP99287:STM2036-MONOMER
- GO:   GO:0005622
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR018771
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF10114 Hist_Kin_Sens; PF00165 HTH_AraC; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 34415; Mature: 34415

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRC
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCCHHHC
RMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNIL
CHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEEEEE
NVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSEA
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHC
NKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
VNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHP
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
PSL
CCC
>Mature Secondary Structure
MISASALNSELINKIAQDFAQATGLAVVVVNIHGDEISELFNFTPFCQLMRQHPQHSTRC
CCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHHCCCHHHHHHHHCCCCHHHC
RMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVGFVLCGQVRLSNDVELVNIL
CHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCEEEEEE
NVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVENCLKKQLNFVVIKDNPQQSEA
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHC
NKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASHVYLSPYYFSKLFKKYQGIGFNAW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCHHH
VNRQRMVSARELLCHSDWSIASIARNLGFSQTSYFCKVFRQTYQVTPQAYRQQINENSHP
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
PSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8071226; 9352910; 11677609; 8501034