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The map label for this gene is cheM

Identifier: 16765261

GI number: 16765261

Start: 2014756

End: 2016417

Strand: Reverse

Name: cheM

Synonym: STM1919

Alternate gene names: 16765261

Gene position: 2016417-2014756 (Counterclockwise)

Preceding gene: 16765262

Following gene: 16765260

Centisome position: 41.51

GC content: 55.54

Gene sequence:

>1662_bases
ATGTTTAACCGTATCCGCGTTGTCACAATGCTGATGATGGTGCTGGGGGTTTTCGCACTGCTACAGCTTGTTTCCGGTGG
TTTGCTGTTTTCTTCATTACAGCATAACCAGCAAGGTTTTGTTATTTCTAACGAATTACGTCAGCAACAAAGCGAACTCA
CGTCGACATGGGACTTAATGCTGCAAACGCGCATTAACCTGAGCCGCTCCGCCGCACGCATGATGATGGACGCTTCTAAC
CAGCAGAGCAGCGCCAAAACGGATTTACTCCAGAATGCAAAAACGACTCTCGCACAGGCGGCGGCGCACTACGCCAATTT
CAAAAATATGACGCCATTGCCAGCGATGGCGGAGGCCAGCGCGAACGTCGATGAAAAATATCAGCGCTATCAGGCCGCAT
TAGCCGAACTTATTCAGTTTCTGGACAATGGCAATATGGATGCCTACTTCGCCCAGCCAACCCAGGGAATGCAAAACGCG
TTGGGCGAGGCGCTGGGCAATTACGCCCGGGTGAGCGAAAACCTGTACCGCCAGACATTTGATCAAAGTGCTCATGACTA
CCGTTTTGCGCAATGGCAACTGGGGGTTCTTGCGGTCGTGCTGGTGCTGATTTTGATGGTGGTTTGGTTCGGCATTCGTC
ATGCCCTGCTTAACCCATTAGCGCGAGTGATTACTCATATCCGTGAAATTGCCAGCGGCGATCTGACGAAAACGCTCACC
GTCTCAGGACGTAATGAAATTGGCGAACTGGCGGGAACGGTTGAACATATGCAACGCTCGCTGATTGACACCGTAACGCA
GGTTCGTGAAGGTTCGGATGCGATTTATTCCGGCACCAGTGAAATTGCCGCCGGTAATACCGACCTCTCTTCCCGTACCG
AACAGCAGGCCTCCGCTCTGGAGGAGACGGCTGCCAGCATGGAACAACTGACGGCCACCGTGAAGCAAAACGCCGATAAC
GCCCGCCAGGCTTCGCAACTGGCGCAAAGCGCCTCCGAGACCGCGCGTCATGGCGGCAAAGTGGTCGACGGCGTAGTAAA
CACTATGCACGAAATTGCCGACAGTTCGAAAAAAATCGCTGACATTATCAGCGTTATCGACGGTATTGCCTTCCAGACTA
ACATTCTGGCGCTGAACGCGGCGGTAGAAGCGGCGCGCGCGGGAGAGCAGGGGCGCGGTTTTGCGGTCGTGGCAGGCGAG
GTGCGTAATCTGGCCAGCCGCAGCGCCCAGGCGGCGAAAGAAATAAAAGCGTTGATTGAAGATTCCGTCTCGCGTGTCGA
TACCGGTTCTGTGCTGGTGGAAAGCGCCGGGGAAACCATGACTGACATCGTCAATGCCGTTACGCGCGTCACGGATATCA
TGGGCGAAATCGCCTCCGCCTCGGATGAGCAAAGCCGGGGTATCGATCAGGTCGCTTTGGCCGTTTCCGAAATGGATCGC
GTAACGCAACAGAACGCCTCGCTGGTTCAGGAATCCGCAGCGGCCGCCGCCGCGCTGGAAGAGCAGGCCAGCCGTCTGAC
CCAGGCGGTATCGGCTTTCCGCCTGGCATCGCGACCGCTGGCGGTAAATAAACCTGAGATGCGTTTGTCAGTGAACGCTC
AGTCCGGCAATACGCCGCAGTCATTAGCCGCCAGGGATGATGCGAACTGGGAAACCTTCTGA

Upstream 100 bases:

>100_bases
CAATGTCGTCTTCCGGAACAGCGTATTTCCTTTTTGCAAAAGTAAAGTTATCACCGCAGGTGCCGATAACGTTGATAACT
CGTTATCAGGAAGGTGCCTT

Downstream 100 bases:

>100_bases
TCGACGTGCGCTGTCGGTTATCGATTAATTTGCGAACCCGCCGATACCTTTCGTCTGGTTCGCATAGATAAAAGCAAAAA
ATGTGTAATACGGGAAGCAT

Product: methyl accepting chemotaxis protein II

Products: NA

Alternate protein names: MCP-II; Aspartate chemoreceptor protein

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASN
QQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNA
LGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLT
VSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADN
ARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQSLAARDDANWETF

Sequences:

>Translated_553_residues
MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASN
QQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNA
LGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLT
VSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADN
ARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQSLAARDDANWETF
>Mature_553_residues
MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASN
QQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNA
LGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLT
VSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADN
ARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQSLAARDDANWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI1788195, Length=554, Percent_Identity=79.0613718411552, Blast_Score=822, Evalue=0.0,
Organism=Escherichia coli, GI2367378, Length=557, Percent_Identity=59.245960502693, Blast_Score=574, Evalue=1e-165,
Organism=Escherichia coli, GI1788194, Length=523, Percent_Identity=48.1835564053537, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1787690, Length=542, Percent_Identity=46.1254612546125, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1789453, Length=347, Percent_Identity=39.4812680115274, Blast_Score=222, Evalue=6e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MCP2_SALTY (P02941)

Other databases:

- EMBL:   J01809
- EMBL:   AE006468
- PIR:   A03441
- RefSeq:   NP_460876.1
- PDB:   1JMW
- PDB:   1LIH
- PDB:   1VLS
- PDB:   1VLT
- PDB:   1WAS
- PDB:   1WAT
- PDB:   2LIG
- PDBsum:   1JMW
- PDBsum:   1LIH
- PDBsum:   1VLS
- PDBsum:   1VLT
- PDBsum:   1WAS
- PDBsum:   1WAT
- PDBsum:   2LIG
- ProteinModelPortal:   P02941
- PRIDE:   P02941
- GeneID:   1253440
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1919
- NMPDR:   fig|99287.1.peg.1859
- HOGENOM:   HBG752668
- OMA:   MDAYFAQ
- ProtClustDB:   PRK15048
- BioCyc:   STYP99287:STM1919-MONOMER
- GO:   GO:0006935
- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660
- Gene3D:   G3DSA:1.20.120.30
- PRINTS:   PR00260
- SMART:   SM00304
- SMART:   SM00283
- SMART:   SM00319

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH; SSF47170 Chemotax_Me-accpt_rcpt_lig-bd

EC number: NA

Molecular weight: Translated: 59615; Mature: 59615

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00538 CHEMOTAXIS_TRANSDUC_1; PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf745a34)-; HASH(0xeccd194)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLM
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
LQTRINLSRSAARMMMDASNQQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHC
ANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNALGEALGNYARVSENLYRQTF
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLT
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASAL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHH
EETAASMEQLTATVKQNADNARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
DSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
HHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHH
SLAARDDANWETF
HHHHCCCCCCCCH
>Mature Secondary Structure
MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISNELRQQQSELTSTWDLM
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHH
LQTRINLSRSAARMMMDASNQQSSAKTDLLQNAKTTLAQAAAHYANFKNMTPLPAMAEAS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHC
ANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNALGEALGNYARVSENLYRQTF
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLNPLARVITHIREIASGDLTKTLT
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VSGRNEIGELAGTVEHMQRSLIDTVTQVREGSDAIYSGTSEIAAGNTDLSSRTEQQASAL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCHHHHHHHHHHHH
EETAASMEQLTATVKQNADNARQASQLAQSASETARHGGKVVDGVVNTMHEIADSSKKIA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
DSVSRVDTGSVLVESAGETMTDIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDR
HHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHH
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLASRPLAVNKPEMRLSVNAQSGNTPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHH
SLAARDDANWETF
HHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6302843; 11677609; 1660187; 8486661; 8831788