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The map label for this gene is flhB

Identifier: 16765256

GI number: 16765256

Start: 2010283

End: 2011434

Strand: Reverse

Name: flhB

Synonym: STM1914

Alternate gene names: 16765256

Gene position: 2011434-2010283 (Counterclockwise)

Preceding gene: 16765257

Following gene: 16765255

Centisome position: 41.41

GC content: 55.9

Gene sequence:

>1152_bases
GTGGCAGAAGAGAGCGACGACGACAAAACAGAAGCCCCCACACCCCACCGACTTGAAAAAGCGCGGGAAGAAGGGCAGAT
CCCCCGTTCCAGAGAACTGACCTCACTGCTGATATTGCTGGTGGGCGTTTGTATTATTTGGTTCGGCGGCGAGTCGTTAG
CGCGGCAGCTGGCGGGAATGCTCTCAGCAGGCCTGCACTTCGATCACCGTATGGTGAACGATCCTAACCTGATCCTGGGG
CAGATAATTTTGCTGATTAAAGCGGCGATGATGGCACTGCTACCGCTCATCGCGGGCGTGGTGCTGGTGGCGCTTATCTC
GCCGGTTATGCTTGGCGGCCTGATTTTTAGCGGTAAGTCGCTACAGCCAAAATTTTCTAAATTAAACCCGCTGCCGGGAA
TTAAGCGCATGTTTTCGGCGCAGACCGGCGCGGAATTGCTAAAAGCGGTGTTGAAATCCACGCTGGTCGGCTGCGTTACC
GGCTTTTATCTCTGGCATCACTGGCCGCAAATGATGCGCCTGATGGCGGAGTCGCCGATCGTCGCAATGGGGAATGCGCT
GGATCTGGTTGGACTCTGCGCGTTACTGGTGGTACTGGGCGTGATTCCGATGGTGGGATTTGACGTGTTTTTCCAGATCT
TTAGCCACCTGAAAAAATTACGCATGTCGCGGCAGGACATTCGCGACGAATTTAAAGAGAGCGAAGGCGATCCGCATGTT
AAGGGCAAAATTCGCCAGATGCAACGCGCCGCCGCGCAGCGCCGCATGATGGAAGATGTGCCGAAAGCGGACGTCATTGT
CACTAACCCGACGCACTATTCCGTGGCGCTGCAGTATGACGAAAACAAAATGAGCGCGCCGAAAGTGGTCGCGAAGGGGG
CTGGATTAATAGCGCTGCGCATTCGCGAGATCGGCGCTGAACATCGGGTTCCCACTTTAGAAGCGCCGCCGCTGGCGCGG
GCATTATATCGCCACGCCGAAATCGGTCAGCAAATTCCCGGGCAGTTATATGCTGCCGTTGCGGAAGTGTTGGCCTGGGT
CTGGCAGCTTAAACGCTGGCGGCTTGCGGGCGGGCAACGTCCTCCACAACCTGAGAACCTTCCGGTGCCAGAAGCGCTGG
ATTTTATGAACGAGAAGAATACTGATGGCTAA

Upstream 100 bases:

>100_bases
TAACGCCATAAACCCCGCCTTTTTTACCGCTTACTCTGCCTATTGGCGTAAAGCGGTTCTGGCATCATTCTCTCTTATCA
ATCTATCCAGGGTTTGCTGC

Downstream 100 bases:

>100_bases
TCTGGTCGCGATGCTGCGCCTGCCCAGCAACCTGAAATCGACGCAATGGCAAATTCTTGCCGGGCCGATCCTCATTCTGC
TGATTTTGTCGATGATGGTG

Product: flagellar biosynthesis protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MAEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGMLSAGLHFDHRMVNDPNLILG
QIILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVT
GFYLWHHWPQMMRLMAESPIVAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHV
KGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALRIREIGAEHRVPTLEAPPLAR
ALYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQRPPQPENLPVPEALDFMNEKNTDG

Sequences:

>Translated_383_residues
MAEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGMLSAGLHFDHRMVNDPNLILG
QIILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVT
GFYLWHHWPQMMRLMAESPIVAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHV
KGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALRIREIGAEHRVPTLEAPPLAR
ALYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQRPPQPENLPVPEALDFMNEKNTDG
>Mature_382_residues
AEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGMLSAGLHFDHRMVNDPNLILGQ
IILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVTG
FYLWHHWPQMMRLMAESPIVAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHVK
GKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALRIREIGAEHRVPTLEAPPLARA
LYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQRPPQPENLPVPEALDFMNEKNTDG

Specific function: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family

Homologues:

Organism=Escherichia coli, GI1788188, Length=381, Percent_Identity=90.5511811023622, Blast_Score=657, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLHB_SALTY (P40727)

Other databases:

- EMBL:   D32203
- EMBL:   AE006468
- EMBL:   M16691
- PIR:   A55546
- RefSeq:   NP_460871.1
- ProteinModelPortal:   P40727
- SMR:   P40727
- GeneID:   1253435
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1914
- NMPDR:   fig|99287.1.peg.1854
- HOGENOM:   HBG529770
- OMA:   VYQLRRF
- ProtClustDB:   PRK05702
- BioCyc:   STYP99287:STM1914-MONOMER
- InterPro:   IPR006136
- InterPro:   IPR006135
- PRINTS:   PR00950
- TIGRFAMs:   TIGR00328

Pfam domain/function: PF01312 Bac_export_2

EC number: NA

Molecular weight: Translated: 42356; Mature: 42224

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb7af4c4)-; HASH(0xb908624)-; HASH(0xf25537c)-; HASH(0xf20a804)-; HASH(0xb8ce69c)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGM
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSAGLHFDHRMVNDPNLILGQIILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKS
HHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVTGFYLWHHWPQMMRLMAESPI
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALR
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCCCCHHHH
IREIGAEHRVPTLEAPPLARALYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQR
HHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPQPENLPVPEALDFMNEKNTDG
CCCCCCCCCHHHHHHHCCCCCCH
>Mature Secondary Structure 
AEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGM
CCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LSAGLHFDHRMVNDPNLILGQIILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKS
HHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVTGFYLWHHWPQMMRLMAESPI
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
KGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALR
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCCCCHHHH
IREIGAEHRVPTLEAPPLARALYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQR
HHHHCHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPQPENLPVPEALDFMNEKNTDG
CCCCCCCCCHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002587; 11677609; 3298217