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The map label for this gene is recE [H]

Identifier: 16765212

GI number: 16765212

Start: 1966514

End: 1967008

Strand: Direct

Name: recE [H]

Synonym: STM1870

Alternate gene names: 16765212

Gene position: 1966514-1967008 (Clockwise)

Preceding gene: 16765209

Following gene: 16765218

Centisome position: 40.48

GC content: 52.32

Gene sequence:

>495_bases
GTGGAACAGGACACAACTGAACATCATCCGGACCCACAGCCGCTGGAGAATGAACCACCTGTAAGCCAGACAGAAGCAGG
CTACCAGAAAATACGGGCAGAACTGCACGAAGCACGTAAAAACATTCCACCCAAAAACCCGGTTGATGTTGGTAAACAAC
TGGCAGCCGCGCGCGGTGAATATGTCGAAGACATCAGCGACCCGAACGATCCGAGGTGGGTTCATAACAATTACAGCGCC
TCAAATCAGGGTGAAAAAGAAGAAGTGGTGCCGGAGGGAAAACAACCAGCAGCAGAGCCGGAGGCTGTCACCAGAAACGC
GGACGGGACTTTCGATGTATCAGCGCTATTCCTGCCCCCCTCAAACCAGACCGAAAAAACGGAAGCCAGAACAGAAAGAG
ATGGAGAAACGCCGAAAGAGAGCAACCAGCAGGAAACGGCTGGCGATACAGGACAGGAAATTACAACGGACGGTGGATCA
GGTACAACTTCATAG

Upstream 100 bases:

>100_bases
CAAATGTCTGCGGGATATTGAGGCAGGGAGATTTCAGTGTGATGAAGAAAAACAGCAACCGACAGGCGAACTGGCAGATG
AACCAGCAACGCCTGAAGCA

Downstream 100 bases:

>100_bases
CGCAAAACCACACGCCAGTGGCGCTTATTGAAAAACTAAAAGGAACGGACTCATTCACTGTGTCCGCATGGATTGATCGC
TATGAGGTTTTATTACAGCG

Product: RecE-like protein

Products: 5'-Phosphomononucleotides [C]

Alternate protein names: Exodeoxyribonuclease VIII; EXO VIII [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MEQDTTEHHPDPQPLENEPPVSQTEAGYQKIRAELHEARKNIPPKNPVDVGKQLAAARGEYVEDISDPNDPRWVHNNYSA
SNQGEKEEVVPEGKQPAAEPEAVTRNADGTFDVSALFLPPSNQTEKTEARTERDGETPKESNQQETAGDTGQEITTDGGS
GTTS

Sequences:

>Translated_164_residues
MEQDTTEHHPDPQPLENEPPVSQTEAGYQKIRAELHEARKNIPPKNPVDVGKQLAAARGEYVEDISDPNDPRWVHNNYSA
SNQGEKEEVVPEGKQPAAEPEAVTRNADGTFDVSALFLPPSNQTEKTEARTERDGETPKESNQQETAGDTGQEITTDGGS
GTTS
>Mature_164_residues
MEQDTTEHHPDPQPLENEPPVSQTEAGYQKIRAELHEARKNIPPKNPVDVGKQLAAARGEYVEDISDPNDPRWVHNNYSA
SNQGEKEEVVPEGKQPAAEPEAVTRNADGTFDVSALFLPPSNQTEKTEARTERDGETPKESNQQETAGDTGQEITTDGGS
GTTS

Specific function: Is involved in the recE pathway of recombination. Has a strong preference for linear duplex substrate DNA and appears to be unable to initiate degradation from single-stranded breaks in DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787612, Length=100, Percent_Identity=56, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010584 [H]

Pfam domain/function: PF06630 Exonuc_VIII [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 17888; Mature: 17888

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQDTTEHHPDPQPLENEPPVSQTEAGYQKIRAELHEARKNIPPKNPVDVGKQLAAARGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YVEDISDPNDPRWVHNNYSASNQGEKEEVVPEGKQPAAEPEAVTRNADGTFDVSALFLPP
HHHHCCCCCCCCEECCCCCCCCCCCCHHCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECC
SNQTEKTEARTERDGETPKESNQQETAGDTGQEITTDGGSGTTS
CCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MEQDTTEHHPDPQPLENEPPVSQTEAGYQKIRAELHEARKNIPPKNPVDVGKQLAAARGE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
YVEDISDPNDPRWVHNNYSASNQGEKEEVVPEGKQPAAEPEAVTRNADGTFDVSALFLPP
HHHHCCCCCCCCEECCCCCCCCCCCCHHCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECC
SNQTEKTEARTERDGETPKESNQQETAGDTGQEITTDGGSGTTS
CCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Double-Stranded DNA [C]

Specific reaction: Degradation Of Double-Stranded DNA. It Acts Progressively In A 5' To 3' Direction, Releasing 5'-Phosphomononucleotides. [C]

General reaction: Hydrolase; Acting on ester bonds; Exodeoxyribonucleases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2649487; 2199308; 8244937 [H]