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The map label for this gene is pagO

Identifier: 16765203

GI number: 16765203

Start: 1959507

End: 1960421

Strand: Direct

Name: pagO

Synonym: STM1862

Alternate gene names: 16765203

Gene position: 1959507-1960421 (Clockwise)

Preceding gene: 39546329

Following gene: 16765204

Centisome position: 40.34

GC content: 41.2

Gene sequence:

>915_bases
ATGCGCAAGGTGTCGATATCTATATTATTCATGCTAGTTTCACTGACTTGGGGGACTACATGGTTGGCCATGCGAATTGC
CGTTGAAACTATCCCTCCAGTGTTTGCAACCGGAATGAGGTTTATGTTTGCAGCACCTTTTTTAATCATCATTGCATGGT
TAAGAAAAAAAACACTGTTGTTTCCTCCCGGACAACGATTATTCCAGTTTGTGATATGCATCTTTTATTTTTGCATTCCT
TTCTCACTAATGATTTATGGTGAAACCTATGTCAACTCTGGGCTTGCCGCCATTATCTTTGCGAATATGCCTGTGGCCGT
TTTGATAGCATCGGTTTTGTTTCTAAATGAAAAAGCGAAACTAATGCAGATCGCGGGCTTAACTATCGCAATCACTGCAT
TGACGGGGATACTTCTTGAAGAAACGAATACAAGTACAGAGAGTCACTGGCAGGGTATCACTGCGCTTATTTCTGCTGTG
TTAATCCATGCCATAATATATACACAATGTAAGAAAAGAAGTTGTACTGTCTCTGTTATCACATTTAATGCGCTCCCGTG
CCTTTTAGCTGGGTTGATACTTTCTGCGACAGGATGGTTTTTTGAAAGACCACAAGTATCAACCTTCTCAGTACACTCAA
TATTAGCTACCCTGTATCTCGGGGCTTTTGCCGGAGTTTTTGGTATCCTGTGCTACTTTGCGCTTCAGCAAAAGGCTAAT
GCCTTCCAGGCTTCGCTTGTATTTCTTATCTTTCCGCTGATTGCGGTAAGTCTGGAAGACTATATTTATGGATATGCTAT
TTCAACACACTCAATGCTGCTTATTATACCATTAGTTATCGGGATATTTCTTACTCTTGTCGCCAGAAATCTCCCTGTAA
CCAGCAGATGCCGGGATAACTCATCACAGAAATAA

Upstream 100 bases:

>100_bases
ATAGAGAAATTTTTATCTAAACATATAAAAAACACAGTGAAGAAAACGCTACTTTTTTCTAGCTAAAAAGCTAAATTAAT
TTTTTTACGGAGAGGATCTT

Downstream 100 bases:

>100_bases
TCGATTTATAATAACGCAAATAATTCCTGATGCCTTACTGAGCTCCGGCTAATGCGGGGTGGATAAGCTGGAATACAGAC
CCGGTAATACACAGCGATTA

Product: integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFAAPFLIIIAWLRKKTLLFPPGQRLFQFVICIFYFCIP
FSLMIYGETYVNSGLAAIIFANMPVAVLIASVLFLNEKAKLMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAV
LIHAIIYTQCKKRSCTVSVITFNALPCLLAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKAN
AFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLVIGIFLTLVARNLPVTSRCRDNSSQK

Sequences:

>Translated_304_residues
MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFAAPFLIIIAWLRKKTLLFPPGQRLFQFVICIFYFCIP
FSLMIYGETYVNSGLAAIIFANMPVAVLIASVLFLNEKAKLMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAV
LIHAIIYTQCKKRSCTVSVITFNALPCLLAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKAN
AFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLVIGIFLTLVARNLPVTSRCRDNSSQK
>Mature_304_residues
MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFAAPFLIIIAWLRKKTLLFPPGQRLFQFVICIFYFCIP
FSLMIYGETYVNSGLAAIIFANMPVAVLIASVLFLNEKAKLMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAV
LIHAIIYTQCKKRSCTVSVITFNALPCLLAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKAN
AFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLVIGIFLTLVARNLPVTSRCRDNSSQK

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAGO_SALTY (O30646)

Other databases:

- EMBL:   AF013775
- EMBL:   AE006468
- RefSeq:   NP_460818.1
- GeneID:   1253381
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1862
- NMPDR:   fig|99287.1.peg.1802
- HOGENOM:   HBG303466
- OMA:   WIAMKIA
- ProtClustDB:   CLSK862159
- BioCyc:   STYP99287:STM1862-MONOMER
- InterPro:   IPR000620

Pfam domain/function: PF00892 DUF6

EC number: NA

Molecular weight: Translated: 33623; Mature: 33623

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf544a34)-; HASH(0xdf8fe44)-; HASH(0xb8b7180)-; HASH(0xdf8d8dc)-; HASH(0xf451be4)-; HASH(0xf18345c)-; HASH(0xf548984)-; HASH(0xb203a98)-; HASH(0xeaa45b4)-; HASH(0xe932bd8)-;

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFAAPFLIIIAWLRKKTLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FPPGQRLFQFVICIFYFCIPFSLMIYGETYVNSGLAAIIFANMPVAVLIASVLFLNEKAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCHHHHHHHHHHHCCHHH
LMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAVLIHAIIYTQCKKRSCTVSVI
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TFNALPCLLAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKAN
EHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLVIGIFLTLVARNLPVTSRCRDN
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
SSQK
CCCH
>Mature Secondary Structure
MRKVSISILFMLVSLTWGTTWLAMRIAVETIPPVFATGMRFMFAAPFLIIIAWLRKKTLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FPPGQRLFQFVICIFYFCIPFSLMIYGETYVNSGLAAIIFANMPVAVLIASVLFLNEKAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHCCCCCHHHHHHHHHHHCCHHH
LMQIAGLTIAITALTGILLEETNTSTESHWQGITALISAVLIHAIIYTQCKKRSCTVSVI
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TFNALPCLLAGLILSATGWFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKAN
EHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQASLVFLIFPLIAVSLEDYIYGYAISTHSMLLIIPLVIGIFLTLVARNLPVTSRCRDN
HHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCC
SSQK
CCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9712687; 11677609