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The map label for this gene is ycgR

Identifier: 16765139

GI number: 16765139

Start: 1897268

End: 1898002

Strand: Direct

Name: ycgR

Synonym: STM1798

Alternate gene names: 16765139

Gene position: 1897268-1898002 (Clockwise)

Preceding gene: 16765137

Following gene: 16765141

Centisome position: 39.06

GC content: 52.65

Gene sequence:

>735_bases
GTGAGTGGTTACAATGAGCAGTTCCTGAAAAAAAATCCATTAGCGATATTAGGCGTGCTACGGGATTTAAATAAAAATCA
GGTTCCACTGCGTATTTCATGGGCGCATGGTCAATTCATCAGTAAAATTTTGGCGGTAGACCCGGAAAAACTCATCGTGG
ATTACGGCAGCCAGGAATACGAAAATAGCGCCGTATTACGTGCCGGGCAGGTAGCCATTATCGCAGAAACGCAGGGCGCA
AAAGTCGAGTTCACGTTGCCGCAACTCGTTACAGGCGAATATCAGCGGCTGCCGGCCTTTATCACGCCCCTGCCGTCGTC
ACTGTGGTTTGTCCAGCGCCGGGAGTATTTTCGCATTGGCGCGCCGCTGTATCCGCCTTATTACGGCGTCACCACGCTAC
CGGACACCCGTACGTTACGTTTTCGCCTGTTTGATCTTTCCCTGGGCGGCATGGGCGCGCTACTGGAATCCGCCATCCCC
GACGGACTAATCGAAGGCGCACGCTTTTCGCAGGTTGAACTGAACATGGGGCAATGGGGGATTTTTCACGTTGACGCCCA
GCTTATCTCCATCAGCGAGCGTAAGGTGATTGATGGGAAAAATGAAACGATCACCACTCCCCGCCTGAGCTTTCGTTTCC
TTAACGTTAGCCCGGCGGTGGAGCGGGAGTTGCAGCGGATTATTTTTTCGCTTGAGCGCGAGGCCCGAGAAAGAGCGAAT
AAAGTGCGAGAATAA

Upstream 100 bases:

>100_bases
TGATTTATCTCGCGGACATAAAAATTTATTTATCGCTATTAAGTTCTTTCTACCGATGCCGATAACCCAACGATAGTCTG
CGTATCAGGGGTTATTTCGT

Downstream 100 bases:

>100_bases
TCTTCACGCTAAACTACATGGCGTCCAGCGCCTGCTGAAGCTTCCAGATATAGCGCGGCGCCTGCGGCGCGGGATGATTA
TCAACAACATGTTCAAAAAA

Product: inner membrane protein

Products: NA

Alternate protein names: Cyclic di-GMP binding protein YcgR

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEYENSAVLRAGQVAIIAETQGA
KVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIP
DGLIEGARFSQVELNMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERAN
KVRE

Sequences:

>Translated_244_residues
MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEYENSAVLRAGQVAIIAETQGA
KVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIP
DGLIEGARFSQVELNMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERAN
KVRE
>Mature_243_residues
SGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEYENSAVLRAGQVAIIAETQGAK
VEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPD
GLIEGARFSQVELNMGQWGIFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERANK
VRE

Specific function: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Overexpression of this gene decreases swimming and swarming motility; those cells that are motile turn predominantly counterc

COG id: COG5581

COG function: function code M; Predicted glycosyltransferase

Gene ontology:

Cell location: Bacterial flagellum basal body. Note=Localization lost in FliM mutants E-155 or E-160

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI1787443, Length=244, Percent_Identity=72.5409836065574, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCGR_SALTY (Q8ZP19)

Other databases:

- EMBL:   AE006468
- RefSeq:   NP_460754.1
- ProteinModelPortal:   Q8ZP19
- SMR:   Q8ZP19
- PRIDE:   Q8ZP19
- GeneID:   1253317
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1798
- NMPDR:   fig|99287.1.peg.1739
- HOGENOM:   HBG436770
- OMA:   AGLHEGM
- ProtClustDB:   CLSK2301992
- BioCyc:   STYP99287:STM1798-MONOMER
- HAMAP:   MF_01457
- InterPro:   IPR009875
- InterPro:   IPR009926

Pfam domain/function: PF07238 PilZ; PF07317 YcgR

EC number: NA

Molecular weight: Translated: 27668; Mature: 27537

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEY
CCCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCHHEEEECCCCCC
ENSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIG
CCCCEEEECCEEEEEECCCCEEEEECHHHHCCCHHHCCCEECCCCCHHHHHHHHCEEEEC
APLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVELNMGQWG
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHCCCCEEEEEECCCCCE
IFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERAN
EEEECEEEEEECCCEEECCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
KVRE
HCCC
>Mature Secondary Structure 
SGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKILAVDPEKLIVDYGSQEY
CCCCCHHHHCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHCCCHHEEEECCCCCC
ENSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFITPLPSSLWFVQRREYFRIG
CCCCEEEECCEEEEEECCCCEEEEECHHHHCCCHHHCCCEECCCCCHHHHHHHHCEEEEC
APLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIPDGLIEGARFSQVELNMGQWG
CCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHCCCCEEEEEECCCCCE
IFHVDAQLISISERKVIDGKNETITTPRLSFRFLNVSPAVERELQRIIFSLEREARERAN
EEEECEEEEEECCCEEECCCCCEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
KVRE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609