Click here to switch to the map view.

The map label for this gene is sapA

Identifier: 16765035

GI number: 16765035

Start: 1783678

End: 1785327

Strand: Direct

Name: sapA

Synonym: STM1692

Alternate gene names: 16765035

Gene position: 1783678-1785327 (Clockwise)

Preceding gene: 16765034

Following gene: 16765036

Centisome position: 36.72

GC content: 54.12

Gene sequence:

>1650_bases
ATGCGCCTGGTTTTATCGTCTCTGATCGTGATAGCGGGTCTACTAAGTAGTCAGGCTACGGCTGCGACTGCGCCCGAACA
AACTGCGAGTGCAGATATTCGCGATAGCGGCTTTGTGTATTGTGTCAGCGGGCAGGTCAACACCTTTAATCCGCAAAAAG
CGAGCAGCGGCCTCATCGTCGATACCCTGGCCGCCCAGTTATATGATCGCCTGTTGGATGTCGATCCCTATACTTATCGT
TTAGTCCCAGAGCTGGCAGAAAGCTGGGAAGTGCTGGATAACGGGGCAACGTACCGTTTTCACCTGCGCCGCGACGTTTC
CTTTCAAAAAACCGCCTGGTTTACGCCGACCCGAAAACTCAATGCTGATGATGTCGTCTTTACCTTTCAGCGGATTTTCG
ATCGTCGACATCCGTGGCATAACATCAACGGCAGTAGCTTCCCCTACTTTGATAGCCTACAGTTCGCCGACAATGTAAAA
AGCGTGCGTAAGCTGGACAATAACACCGTTGAGTTTCGCCTGACGCAGCCAGACGCCTCCTTTTTATGGCATCTGGCTAC
ACACTACGCTTCCGTCATGTCCGCTGAGTACGCCGCGCAGCTTAGCCGAAAAGATCGTCAGGAACTGCTAGACCGCCAAC
CGGTCGGTACCGGGCCTTTCCAGCTTTCGGAGTACCGTGCCGGGCAGTTTATTCGTCTCCAGCGCCACGATGGGTTTTGG
CGCGGCAAACCGCTGATGCCGCAAGTGGTGGTGGATTTAGGCTCCGGCGGTACCGGGCGTTTATCGAAATTACTGACCGG
TGAATGCGATGTTCTGGCCTGGCCCGCCGCCAGCCAGCTAACTATTTTACGCGACGATCCGCGTTTACGTCTGACGTTGC
GCCCGGGGATGAATATCGCCTATCTGGCCTTTAACACCGATAAGCCGCCGTTGAATAATCCCGCAGTGCGCCATGCGCTG
GCCTTATCGATCAACAACCAGCGCCTGATGCAGTCGATTTATTACGGCACGGCGGAAACCGCAGCCTCCATTTTACCGAG
AGCCTCATGGGCTTACGATAACGATGCCAAAATTACGGAGTACAATCCGCAAAAATCGCGCGAACAGCTAAAAGCGCTGG
GCATTGAGAATCTTACGCTGCATCTCTGGGTGCCGACCAGTTCTCAGGCCTGGAACCCAAGTCCGCTAAAAACGGCGGAG
CTTATTCAGGCGGATATGGCGCAGGTTGGCGTAAAAGTGGTCATTGTGCCGGTTGAAGGTCGTTTTCAGGAGGCGCGCCT
GATGGATATGAATCACGATCTGACCTTATCCGGCTGGGCCACGGACAGCAACGATCCGGATAGCTTTTTCAGACCGCTGT
TAAGCTGTGCGGCCATCAATTCGCAAACCAATTTCGCCCACTGGTGTAACCCTGAATTTGACAGCGTGCTGCGTAAGGCA
CTGTCGTCGCAGCAGTTGGCTTCGCGCATAGAAGCGTATGAGGAAGCGCAGAATATCCTGGAGAAAGAGCTGCCGATACT
GCCGCTGGCATCATCACTACGCCTGCAGGCTTACCGCTACGATATTAAAGGGCTGGTGTTAAGCCCGTTCGGCAATGCGT
CTTTTGCCGGCGTCTCCCGCGAAAAACACGAAGAGGTGAAAAAACCATGA

Upstream 100 bases:

>100_bases
GCTAATTGACGACATTTACGCCAGTTATCCACCGACATTTTTACGTGGCGGGCCGAAGTGCGATACACTTTGCAAATTGA
ACTTCAAAAACTTAACTATT

Downstream 100 bases:

>100_bases
TTATCTTCACCCTGCGTCGGTTATTGCTGTTGCTGGTGACGCTCTTCTTCCTGACCTTTATCGGCTTTAGCCTGAGCTAT
TTTACGCCGCATGCGCCGCT

Product: peptide transport protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSGQVNTFNPQKASSGLIVDTLAAQLYDRLLDVDPYTYR
LVPELAESWEVLDNGATYRFHLRRDVSFQKTAWFTPTRKLNADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVK
SVRKLDNNTVEFRLTQPDASFLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTGPFQLSEYRAGQFIRLQRHDGFW
RGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLTILRDDPRLRLTLRPGMNIAYLAFNTDKPPLNNPAVRHAL
ALSINNQRLMQSIYYGTAETAASILPRASWAYDNDAKITEYNPQKSREQLKALGIENLTLHLWVPTSSQAWNPSPLKTAE
LIQADMAQVGVKVVIVPVEGRFQEARLMDMNHDLTLSGWATDSNDPDSFFRPLLSCAAINSQTNFAHWCNPEFDSVLRKA
LSSQQLASRIEAYEEAQNILEKELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVSREKHEEVKKP

Sequences:

>Translated_549_residues
MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSGQVNTFNPQKASSGLIVDTLAAQLYDRLLDVDPYTYR
LVPELAESWEVLDNGATYRFHLRRDVSFQKTAWFTPTRKLNADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVK
SVRKLDNNTVEFRLTQPDASFLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTGPFQLSEYRAGQFIRLQRHDGFW
RGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLTILRDDPRLRLTLRPGMNIAYLAFNTDKPPLNNPAVRHAL
ALSINNQRLMQSIYYGTAETAASILPRASWAYDNDAKITEYNPQKSREQLKALGIENLTLHLWVPTSSQAWNPSPLKTAE
LIQADMAQVGVKVVIVPVEGRFQEARLMDMNHDLTLSGWATDSNDPDSFFRPLLSCAAINSQTNFAHWCNPEFDSVLRKA
LSSQQLASRIEAYEEAQNILEKELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVSREKHEEVKKP
>Mature_549_residues
MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSGQVNTFNPQKASSGLIVDTLAAQLYDRLLDVDPYTYR
LVPELAESWEVLDNGATYRFHLRRDVSFQKTAWFTPTRKLNADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVK
SVRKLDNNTVEFRLTQPDASFLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTGPFQLSEYRAGQFIRLQRHDGFW
RGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLTILRDDPRLRLTLRPGMNIAYLAFNTDKPPLNNPAVRHAL
ALSINNQRLMQSIYYGTAETAASILPRASWAYDNDAKITEYNPQKSREQLKALGIENLTLHLWVPTSSQAWNPSPLKTAE
LIQADMAQVGVKVVIVPVEGRFQEARLMDMNHDLTLSGWATDSNDPDSFFRPLLSCAAINSQTNFAHWCNPEFDSVLRKA
LSSQQLASRIEAYEEAQNILEKELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVSREKHEEVKKP

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family

Homologues:

Organism=Escherichia coli, GI1787551, Length=549, Percent_Identity=90.1639344262295, Blast_Score=1006, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=515, Percent_Identity=36.504854368932, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1787052, Length=547, Percent_Identity=27.0566727605119, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1787762, Length=490, Percent_Identity=23.8775510204082, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=23.7903225806452, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787495, Length=549, Percent_Identity=24.2258652094718, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789397, Length=535, Percent_Identity=24.2990654205607, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=24.5810055865922, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SAPA_SALTY (P36634)

Other databases:

- EMBL:   X74212
- EMBL:   AE006468
- PIR:   S39585
- RefSeq:   NP_460650.1
- ProteinModelPortal:   P36634
- SMR:   P36634
- PRIDE:   P36634
- GeneID:   1253210
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1692
- NMPDR:   fig|99287.1.peg.1637
- HOGENOM:   HBG688042
- OMA:   PFLLNEY
- ProtClustDB:   PRK15109
- BioCyc:   STYP99287:STM1692-MONOMER
- InterPro:   IPR000914

Pfam domain/function: PF00496 SBP_bac_5

EC number: NA

Molecular weight: Translated: 61651; Mature: 61651

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSGQVNTFNPQKASSGLIV
CHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHH
DTLAAQLYDRLLDVDPYTYRLVPELAESWEVLDNGATYRFHLRRDVSFQKTAWFTPTRKL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCC
NADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVKSVRKLDNNTVEFRLTQPDAS
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHH
FLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTGPFQLSEYRAGQFIRLQRHDGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCC
RGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLTILRDDPRLRLTLRPGMNIA
CCCCCCHHHEEECCCCCCHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEEEECCCCCEE
YLAFNTDKPPLNNPAVRHALALSINNQRLMQSIYYGTAETAASILPRASWAYDNDAKITE
EEEEECCCCCCCCHHHHEEEEEEECHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEE
YNPQKSREQLKALGIENLTLHLWVPTSSQAWNPSPLKTAELIQADMAQVGVKVVIVPVEG
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCC
RFQEARLMDMNHDLTLSGWATDSNDPDSFFRPLLSCAAINSQTNFAHWCNPEFDSVLRKA
CCCHHHEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LSSQQLASRIEAYEEAQNILEKELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVSR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEEEECEEEECCCCCCCCCCCCH
EKHEEVKKP
HHHHHHCCC
>Mature Secondary Structure
MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSGQVNTFNPQKASSGLIV
CHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHH
DTLAAQLYDRLLDVDPYTYRLVPELAESWEVLDNGATYRFHLRRDVSFQKTAWFTPTRKL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEECCCCCC
NADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVKSVRKLDNNTVEFRLTQPDAS
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHH
FLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTGPFQLSEYRAGQFIRLQRHDGFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEEECCCCCC
RGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAASQLTILRDDPRLRLTLRPGMNIA
CCCCCCHHHEEECCCCCCHHHHHHHCCCCCEEECCCCCCEEEEECCCEEEEEECCCCCEE
YLAFNTDKPPLNNPAVRHALALSINNQRLMQSIYYGTAETAASILPRASWAYDNDAKITE
EEEEECCCCCCCCHHHHEEEEEEECHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEE
YNPQKSREQLKALGIENLTLHLWVPTSSQAWNPSPLKTAELIQADMAQVGVKVVIVPVEG
CCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECCC
RFQEARLMDMNHDLTLSGWATDSNDPDSFFRPLLSCAAINSQTNFAHWCNPEFDSVLRKA
CCCHHHEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LSSQQLASRIEAYEEAQNILEKELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVSR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEEEEECEEEECCCCCCCCCCCCH
EKHEEVKKP
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8223423; 11677609