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The map label for this gene is yeeJ [C]

Identifier: 16765012

GI number: 16765012

Start: 1761200

End: 1763182

Strand: Reverse

Name: yeeJ [C]

Synonym: STM1669

Alternate gene names: 16765012

Gene position: 1763182-1761200 (Counterclockwise)

Preceding gene: 16765013

Following gene: 16765011

Centisome position: 36.3

GC content: 51.54

Gene sequence:

>1983_bases
GTGGTTTTTTCTAAAAAACCCATTACTAAATATATAACCTGGGCCATTGTTACCAGTCAGATTCCACTGCCGGTCATTGC
TGATAGCGATAATGAAATTCAGTCGTGGATTGCGGGGACGGCATCGTCTATTTCTCCGCATCTGCAGGAGGGGACGCTGG
AGGATTATGCCAAAGGAAAAATAAAGGCGTTACCAGGGCAGGCCGCTAATCATCTGGTGAACGAGGGGATAAAGAGCGCT
TTTCCGGAGATTATTTTCCGTGGTGGCGTCAATCTTGAAGATGGCGCGAAATATCGCTCATCAGAGTTCGATATGTTTAT
TCCCGTCCAGGAAACAACATCGTCTTTACTCTTTGGTCAGCTTGGCTTTCGCGACCACGACAACAGCAGTTTCGATGGCC
GCACCTATGTTAACGTTGGTATGGGTTACCGCCAGGAGGTCAATGGATGGCTGCTCGGCGTCAATACGTTTCTGGATGCC
GACATCCGTTATTCCCACTTGCGTGGCGGCATTGGCGGGGAAGTCTATAAAGACAGTCTGGCCTTTTCCGGCAACTATTA
TTTCCCTCTCACCGGCTGGAAAATGTCAGCAGCGCATGAATTACATGATGAGCGTCCGGCATATGGCTTTGATCTGCGAA
CAAAAGGCACGCTCCCCGATTTTCCCTGGTTCAGTGGAGAGCTGACATATGAACAGTATTACGGGGATAAAGTTGATCTA
TTGGGTAACGGTACATTAAGCCGGAATCCCCGCGCCGCAGGTGCGGCTCTGGTCTGGAATCCTGTCCCCTTGCTTGAGGT
CAGAGCAGGATATCGGGACGCCGGTAACGGCGGCTCGCAGGCAGAGGGCGGTCTGAGAGTCAATTATTCCTTCGGTACGC
CGTTACATGAACAGCTTGATTACCGCAACGTTGGGGCGCCGTCGAATACGACTAACCGGCGTGCCTTTGTTGATCGTAAT
TACGATATCGTCATGGCGTATCGGGAGCAGGCCAGCAAAATCCGCATTACGGCAATGCCGGTGTCAGGCCTGTCCGGGAC
GCTGGTGACATTAATGGCGACGGTAGATAGCCGTTACCCGGTTGAGAAGGTTGAGTGGTCGGGTGATGCGGAGCTTCTCG
CCGGACTCCAGCTTCAGGGGAGTCTGGGCAGCGGCCTTATCCTTCCACAACTTCCGCTGACGGCGACCGACGGTCAGGAG
TATAGCCTTTATTTAACGGTGACTGACAGCCGGGGTACTCGCGTGACCTCCGAGCGTATCCCGGTAAGGGTGACACAGGA
TGAGACCAGTTTCCGTTCCTGGATAAATGTTATCAATGACGATGTTCAGGTTGAGGACGGCAACTTTGTCATCAATACGC
CGCTTCCTGCCGGAGAAGAGGGGAAGGTTATTGAGTGGCACTACGTGCGCGAGCGTTCTGAAGAGGAGTGGGCGTCGCTC
AAACCACGTCATATTAAGTATCAATCAGATACGCCGGGTCTGGCATTTAAAGCGCTCGGTGGTACAGAGCGTGACGGCCA
TTGGGTTGAACGGGTTCTGGTGACCCATATCGGCGATGATGCCCGCTCGCTCAAATTACATATTGAAGCAAGCGGACCAG
ACGATAAACATCCGGTGAAGGGTACCGTACTACTACAAGCGCAGTCAGACAGTATTGCGCAGAAGGTCACTTCTGTGGAG
GTGCTTTTTACGCCGGGTACTGAAGAGGCCAACGGAAGCGTTACTGCGCCAGTCGTCGGAACAGAAATGCGAGCCAGAAC
GCTTTGTGTAAATAACACGGACTGTACTGATGCGTTTAATTATCAGTGGGAAATCTCGGATGAAATGAAATCCTGGCAAT
CCGTACCGGGTGCGACAAAGGCCACCTGGCTTCTTCCTTATAGTCTTAATGGGGAATCGCTTCAGAATAAATATATCCGC
GTCAGAATTATTTCTGATAAGGGAAATGCTAAGGGTAATACCGCAACCTCTGATGCGAATTAA

Upstream 100 bases:

>100_bases
AGAATAAACGCGCTATCCGTCGCTGATGGTTATCGCCAAATAAACATCTTATTTAAATACTCCCTCTGCCAGGCAGGGGG
ATATAGCAGGAGACAATACA

Downstream 100 bases:

>100_bases
TGTTTTAAAAAGGATCAACAGTGCGTATGTCGAAACATAATCTTATTATCTATAGCCTGCTTCTGGCGGCTGCGCCGATA
AGCGTCTTGGCGGATTCGTC

Product: invasin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGIKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDNSSFDGRTYVNVGMGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKMSAAHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRITAMPVSGLSGTLVTLMATVDSRYPVEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVINTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTPGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN

Sequences:

>Translated_660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGIKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDNSSFDGRTYVNVGMGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKMSAAHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRITAMPVSGLSGTLVTLMATVDSRYPVEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVINTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTPGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN
>Mature_660_residues
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGKIKALPGQAANHLVNEGIKSA
FPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQLGFRDHDNSSFDGRTYVNVGMGYRQEVNGWLLGVNTFLDA
DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKMSAAHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRN
YDIVMAYREQASKIRITAMPVSGLSGTLVTLMATVDSRYPVEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQE
YSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFVINTPLPAGEEGKVIEWHYVRERSEEEWASL
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVE
VLFTPGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIR
VRIISDKGNAKGNTATSDAN

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=273, Percent_Identity=36.6300366300366, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI145693120, Length=376, Percent_Identity=30.0531914893617, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 72732; Mature: 72732

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGK
CCCCCCCHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCHHCCCHHHCCCHHHHHCCC
IKALPGQAANHLVNEGIKSAFPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQ
EEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHC
LGFRDHDNSSFDGRTYVNVGMGYRQEVNGWLLGVNTFLDADIRYSHLRGGIGGEVYKDSL
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEHHHCCCCCCCEECCCE
AFSGNYYFPLTGWKMSAAHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
EECCCEEEEECCCEEHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEHHHHCCCEEEE
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLD
EECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
YRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKIRITAMPVSGLSGTLVTLMATVDSRYP
CCCCCCCCCCCCCEEEEECCCEEEEEEECCCCEEEEEEEECCCCCCHHHEEEEHHCCCCC
VEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQEYSLYLTVTDSRGTRVTSERI
CCEEECCCCHHEEEEEEEECCCCCCEEECCCCEEECCCCEEEEEEEEECCCCCEEECCCC
PVRVTQDETSFRSWINVINDDVQVEDGNFVINTPLPAGEEGKVIEWHYVRERSEEEWASL
CEEEECCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCEEEEEEHHCCCHHHHHCC
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVK
CCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
GTVLLQAQSDSIAQKVTSVEVLFTPGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFN
EEEEEEECCCHHHHHHEEEEEEECCCCCCCCCCEEECEECCCCEEEEEEECCCCCCCCCC
YQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN
EEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSISPHLQEGTLEDYAKGK
CCCCCCCHHHHEEEEEEECCCCEEEEECCCHHHHHHHHCCCHHCCCHHHCCCHHHHHCCC
IKALPGQAANHLVNEGIKSAFPEIIFRGGVNLEDGAKYRSSEFDMFIPVQETTSSLLFGQ
EEECCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHC
LGFRDHDNSSFDGRTYVNVGMGYRQEVNGWLLGVNTFLDADIRYSHLRGGIGGEVYKDSL
CCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEHHHCCCCCCCEECCCE
AFSGNYYFPLTGWKMSAAHELHDERPAYGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDL
EECCCEEEEECCCEEHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEHHHHCCCEEEE
LGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLD
EECCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHCC
YRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKIRITAMPVSGLSGTLVTLMATVDSRYP
CCCCCCCCCCCCCEEEEECCCEEEEEEECCCCEEEEEEEECCCCCCHHHEEEEHHCCCCC
VEKVEWSGDAELLAGLQLQGSLGSGLILPQLPLTATDGQEYSLYLTVTDSRGTRVTSERI
CCEEECCCCHHEEEEEEEECCCCCCEEECCCCEEECCCCEEEEEEEEECCCCCEEECCCC
PVRVTQDETSFRSWINVINDDVQVEDGNFVINTPLPAGEEGKVIEWHYVRERSEEEWASL
CEEEECCCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCCCCEEEEEEHHCCCHHHHHCC
KPRHIKYQSDTPGLAFKALGGTERDGHWVERVLVTHIGDDARSLKLHIEASGPDDKHPVK
CCCEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCC
GTVLLQAQSDSIAQKVTSVEVLFTPGTEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFN
EEEEEEECCCHHHHHHEEEEEEECCCCCCCCCCEEECEECCCCEEEEEEECCCCCCCCCC
YQWEISDEMKSWQSVPGATKATWLLPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN
EEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]