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The map label for this gene is orf408 [H]

Identifier: 16764732

GI number: 16764732

Start: 1464806

End: 1466032

Strand: Reverse

Name: orf408 [H]

Synonym: STM1382

Alternate gene names: 16764732

Gene position: 1466032-1464806 (Counterclockwise)

Preceding gene: 16764733

Following gene: 16764731

Centisome position: 30.18

GC content: 45.8

Gene sequence:

>1227_bases
ATGTTTAAAGAAGAAAGACGTCATGCCATCATTAATTTACTGATAAAGGATAATAGTGTTAGCGTCAGTAAACTTTCAGA
CCTTTATAAGGTTAGCCAGGAGACTATTCGTTCCGATCTACGCTATTTCCAGAAATCAGGTATGCTTCAGCGTTGCTATG
GCGGAGGGATTTTAAACCGTGACGCGCTGAGTAAGCTTATCACTGAAAATAAGATTGATATCTCCAGCACTATCGCCACG
CCAATCCATCAGGATGCAAAACTGCGCCGGGAAAACCCAAAAAAAGCAGGCAAGGTGTGTGTTTTAGGCTCATTCAATAT
TGATGTTTCAGCAACCGTGCCGTGGTTTCCACAAAGCGGAGAATCCATTCTGGCCAGTCAATTTGGATTCTATCCTGGAG
GTAAAGGAGCCAACCAGGCTTTAGCGGCAAACAACGCTGGCGCTGCGGCACATTTTATTTTTAAAGTGGGCAAAGATCAG
TTCAGCGCATTTGCTATGAATCATATTATTCAATCAGGCATCACCTCATACAGCGCGTATCAAACAGATAAAGCACCCAC
CGGTAGCGCATTGATCTATGTCTCCGCCGTGGATGGCGATAATATTATCGCCATCTACCCTGGCGCCAATATGATGCTCA
CCACGCAAGAGATTAATGAGCAACACCGTTATATCGCCGAGTCTGACGTTATGTTAATGCAGCTCGAAACGAACATTGAA
GCGTTGACTGAATTTATTCGTCTGGGCAAACAAGAAAATAAAATGATCATGCTGAACCCTGCCCCCTATACGAAACAGGT
GACGCATTTATTATCTGATATTGACATCATCACGCCGAATGAAACTGAAGCCTCTTTTTTATCCGGTGTAACCATTACTG
ATATTAATGATGCAAAAAAAGCCGGAAATATTATTCTGCAATCCGGGGTGAAAAAAGTCATCATTACCCTTGGCGCCCGT
GGCTCTCTGATCTGTGAGCACGCCCGCACGTTGTATATTCCTGCGTGGAGCGCCGTGGTAAAAGATGCCGCTGGGGCCGG
TGACGCTTTTAATGGCGCCTTAGCCGCCGCGCTGGCGCGACAAGCAGACATGGTCGCAGCCATTCAATATGCCTCCGCTT
TCGCTTCTCTGGCGGTGGAACAAGTCGGTGCGTCGAGTATGCCTCAGCACTTGCAGGTTTTACATCGAATGCGTACCCAA
TCTAATAAAGTCATTCACATTAATTAA

Upstream 100 bases:

>100_bases
TCATTTGGGGTTACTTCCGGTTGACCGCATAATCTGTGATTGAATTCACCGCATGACAACATTGCCATAAATACAATTCA
ACTCACTACCCGGAGGCAAT

Downstream 100 bases:

>100_bases
CAGGTGACATAATGAAAATTTTATTTATTGGCGAATCCTGGCACATTCATATGATTCACTCTAAAGGTTTTGATAGCTTT
ACATCGAGCAAATATGAAGA

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNRDALSKLITENKIDISSTIAT
PIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSGESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQ
FSAFAMNHIIQSGITSYSAYQTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIE
ALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKKAGNIILQSGVKKVIITLGAR
GSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALARQADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQ
SNKVIHIN

Sequences:

>Translated_408_residues
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNRDALSKLITENKIDISSTIAT
PIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSGESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQ
FSAFAMNHIIQSGITSYSAYQTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIE
ALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKKAGNIILQSGVKKVIITLGAR
GSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALARQADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQ
SNKVIHIN
>Mature_408_residues
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNRDALSKLITENKIDISSTIAT
PIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSGESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQ
FSAFAMNHIIQSGITSYSAYQTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIE
ALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKKAGNIILQSGVKKVIITLGAR
GSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALARQADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQ
SNKVIHIN

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=264, Percent_Identity=35.9848484848485, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI1790193, Length=309, Percent_Identity=35.5987055016181, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI87082343, Length=287, Percent_Identity=25.4355400696864, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081971, Length=276, Percent_Identity=24.2753623188406, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788491, Length=298, Percent_Identity=25.8389261744966, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=297, Percent_Identity=31.986531986532, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319884, Length=333, Percent_Identity=25.5255255255255, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI20128807, Length=305, Percent_Identity=32.4590163934426, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24583886, Length=272, Percent_Identity=30.8823529411765, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 44266; Mature: 44266

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNR
CCCHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCH
DALSKLITENKIDISSTIATPIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSG
HHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCCCC
ESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQFSAFAMNHIIQSGITSYSAY
CHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
QTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIE
CCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCHH
ALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKK
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCEEECCCCCCHHHHCCCEEECCCCHHH
AGNIILQSGVKKVIITLGARGSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALAR
HCCHHHHCCCCEEEEEECCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHH
QADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQSNKVIHIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MFKEERRHAIINLLIKDNSVSVSKLSDLYKVSQETIRSDLRYFQKSGMLQRCYGGGILNR
CCCHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCH
DALSKLITENKIDISSTIATPIHQDAKLRRENPKKAGKVCVLGSFNIDVSATVPWFPQSG
HHHHHHHHCCCCCCHHHHCCCCHHHHHHHHCCCCCCCCEEEEEECCEEEEEECCCCCCCC
ESILASQFGFYPGGKGANQALAANNAGAAAHFIFKVGKDQFSAFAMNHIIQSGITSYSAY
CHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCC
QTDKAPTGSALIYVSAVDGDNIIAIYPGANMMLTTQEINEQHRYIAESDVMLMQLETNIE
CCCCCCCCCEEEEEEEECCCCEEEEECCCCEEEEHHHHHHHHHHHHCCCEEEEEECCCHH
ALTEFIRLGKQENKMIMLNPAPYTKQVTHLLSDIDIITPNETEASFLSGVTITDINDAKK
HHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCEEECCCCCCHHHHCCCEEECCCCHHH
AGNIILQSGVKKVIITLGARGSLICEHARTLYIPAWSAVVKDAAGAGDAFNGALAAALAR
HCCHHHHCCCCEEEEEECCCCCEEECCCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHH
QADMVAAIQYASAFASLAVEQVGASSMPQHLQVLHRMRTQSNKVIHIN
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]