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The map label for this gene is sufA [H]

Identifier: 16764719

GI number: 16764719

Start: 1452315

End: 1452683

Strand: Direct

Name: sufA [H]

Synonym: STM1369

Alternate gene names: 16764719

Gene position: 1452315-1452683 (Clockwise)

Preceding gene: 16764717

Following gene: 16764720

Centisome position: 29.9

GC content: 52.03

Gene sequence:

>369_bases
ATGGAATTGCATTCAGACACGTTTAACCCGGAGGACTTCCCCTGGCAAGGGCTGACGCTAACGCCAGCGGCGGCAGCGCA
CATACGTGAACTGGCAGAAAAGCAGCCGGGCATGTTGGGCGTGCGGTTAAGCGTAAAACAGACGGGATGTGCCGGATTTG
GCTATGTTCTGGATACCGTTCGGGAGCCGGATAAAGACGATCTGGTTTTTGAAGCCGAAGGCGCAAAGCTTTTCGCACCG
TTACAGGCGATGCCTTTTATTGACGGAACAGAAGTGGATTACGTACAGGAAGGGCTGAACCAGTTATTTAAATTTCATAA
CCCCAAAGCCCAGAATGAATGCGGCTGCGGCGAAAGTTTTGGGGTATAG

Upstream 100 bases:

>100_bases
ACCATTTGTTGGAAAGCCCCTGCGGTTAAGGGGTTGAAGTGATAATCATTATCACTAACATGCTGTTATATCCTGGTGAT
TTAGAACGCGAGGTAACTCT

Downstream 100 bases:

>100_bases
GCGGTACTATGTCTCGTAACACTGAAGCAACGGAAGAGGTCGGCATCTGGACAGGCGGACGCCTTAATTACAAAGAAGGA
TTTTTCACGCAACTACCCAC

Product: iron-sulfur cluster assembly scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MELHSDTFNPEDFPWQGLTLTPAAAAHIRELAEKQPGMLGVRLSVKQTGCAGFGYVLDTVREPDKDDLVFEAEGAKLFAP
LQAMPFIDGTEVDYVQEGLNQLFKFHNPKAQNECGCGESFGV

Sequences:

>Translated_122_residues
MELHSDTFNPEDFPWQGLTLTPAAAAHIRELAEKQPGMLGVRLSVKQTGCAGFGYVLDTVREPDKDDLVFEAEGAKLFAP
LQAMPFIDGTEVDYVQEGLNQLFKFHNPKAQNECGCGESFGV
>Mature_122_residues
MELHSDTFNPEDFPWQGLTLTPAAAAHIRELAEKQPGMLGVRLSVKQTGCAGFGYVLDTVREPDKDDLVFEAEGAKLFAP
LQAMPFIDGTEVDYVQEGLNQLFKFHNPKAQNECGCGESFGV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=107, Percent_Identity=39.2523364485981, Blast_Score=86, Evalue=8e-18,
Organism=Homo sapiens, GI160420328, Length=98, Percent_Identity=39.7959183673469, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787974, Length=122, Percent_Identity=84.4262295081967, Blast_Score=223, Evalue=2e-60,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=45.7142857142857, Blast_Score=107, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=36.7924528301887, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=36.7924528301887, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=39.622641509434, Blast_Score=83, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=41.5094339622642, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011298 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13390; Mature: 13390

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHSDTFNPEDFPWQGLTLTPAAAAHIRELAEKQPGMLGVRLSVKQTGCAGFGYVLDTV
CCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
REPDKDDLVFEAEGAKLFAPLQAMPFIDGTEVDYVQEGLNQLFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEECHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GV
CC
>Mature Secondary Structure
MELHSDTFNPEDFPWQGLTLTPAAAAHIRELAEKQPGMLGVRLSVKQTGCAGFGYVLDTV
CCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
REPDKDDLVFEAEGAKLFAPLQAMPFIDGTEVDYVQEGLNQLFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEECHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]