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The map label for this gene is aroE [H]

Identifier: 16764710

GI number: 16764710

Start: 1440420

End: 1441286

Strand: Reverse

Name: aroE [H]

Synonym: STM1359

Alternate gene names: 16764710

Gene position: 1441286-1440420 (Counterclockwise)

Preceding gene: 16764711

Following gene: 16764709

Centisome position: 29.67

GC content: 48.21

Gene sequence:

>867_bases
ATGGATGTTACCGCAAAATATGAATTAATTGGTCTTATGGCGTATCCTATCCGTCATAGCTTATCGCCCGAAATGCAAAA
CAAAGCGTTAGAAAAAGCGGGGCTACCGTATACCTATATGGCTTTCGAAGTGGATAACACGACGTTTGCCAGCGCCATTG
AAGGACTGAAAGCATTAAAAATGCGCGGTACGGGCGTCTCCATGCCAAACAAACAGCTCGCGTGTGAGTATGTCGATGAA
TTAACGCCAGCAGCAAAACTGGTTGGCGCTATCAACACCATTGTTAACGATGACGGCTATCTACGCGGCTACAACACGGA
TGGTACGGGCCATATTCGGGCAATTAAAGAAAGCGGTTTCGATATGCGGGGAAAAACCATGGTGCTGCTCGGCGCGGGAG
GCGCGGCTACCGCCATTGGCGCCCAGGCAGCTATTGAAGGCATTAAGGAAATTAAACTGTTTAACCGTAAAGATGACTTT
TTCGAAAAAGCGGTTGCCTTTGCGAAGCGGGTGAATGAAAACACTGATTGTGTCGTTACCGTCACCGATCTTGCCGATCA
GCACGCTTTTACTGAAGCGCTTGCCAGCGCAGATATTCTGACGAACGGCACCAAAGTTGGCATGAAACCATTGGAGAACG
AATCCCTGATCGGCGATGTTTCCCTGCTCCGCCCTGAATTGCTGGTCACCGAATGTGTTTATAATCCGCATATGACAAAG
TTATTGCAGCAGGCGCAACAAGCTGGTTGCAAAACAATTGATGGTTACGGCATGTTGTTATGGCAAGGAGCCGAACAGTT
TGAACTGTGGACAGGAAAAGCGTTTCCATTGGACTATGTAAAGCAGGTGATGGGATTCACAGCCTGA

Upstream 100 bases:

>100_bases
CGATGTCCGATTTGGCGAGCATTATTTCCAGTAAAAATGTTAACGATGCGCAACAGGCATGCGCCCTGCTCTGCACTGTC
CACTTATTAAGGAGTATAAA

Downstream 100 bases:

>100_bases
CCGGTAAAATTATAATTGCGACGAATGACAATGAAGGGTACCAAATGAAAACCGTAACTGTAAGAGATCTCGTGGTTGGC
GAAGGCGCGCCAAAGATCAT

Product: quinate/shikimate dehydrogenase

Products: NA

Alternate protein names: NAD-dependent shikimate 5-dehydrogenase 2 [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDE
LTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDF
FEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTK
LLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA

Sequences:

>Translated_288_residues
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDE
LTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDF
FEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTK
LLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
>Mature_288_residues
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDE
LTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDF
FEKAVAFAKRVNENTDCVVTVTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTK
LLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=288, Percent_Identity=90.9722222222222, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1789675, Length=272, Percent_Identity=27.5735294117647, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=278, Percent_Identity=28.4172661870504, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR022872
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.282 [H]

Molecular weight: Translated: 31337; Mature: 31337

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHH
MRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGF
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCC
DMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
VTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTK
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
LLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
HHHHHHHCCCCEECCCEEEEECCCCHHEEECCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALK
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHH
MRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGF
CCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCC
DMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKDDFFEKAVAFAKRVNENTDCVVT
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
VTDLADQHAFTEALASADILTNGTKVGMKPLENESLIGDVSLLRPELLVTECVYNPHMTK
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
LLQQAQQAGCKTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFTA
HHHHHHHCCCCEECCCEEEEECCCCHHEEECCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA