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The map label for this gene is nucA [H]

Identifier: 16764681

GI number: 16764681

Start: 1408531

End: 1409385

Strand: Direct

Name: nucA [H]

Synonym: STM1330

Alternate gene names: 16764681

Gene position: 1408531-1409385 (Clockwise)

Preceding gene: 16764680

Following gene: 16764684

Centisome position: 29.0

GC content: 51.35

Gene sequence:

>855_bases
GTGAACAAGACCATTAATTTGCTAAAATTACTGCCCGTAGTATTATTAAGCGCATGTACTACATCGTATCCTCCCCAGGA
TACAACATCGGCACCCGAGTTACCCCATCGTAACGTACTCGTTCAGCAACCTGATAACTGTAGCGTTGGCTGTCCTCAAG
GAGGAAGCCAACAAACAATCTATCGCCATGTCTATACGCTCAATAATAATAGCGTCACGAAATTTGCCAACTGGGTTGCC
TATAGCGTGACAAAAACCAGCCAGGCAAGCGGTCGCCCGCGGAACTGGGCGCAGGACCCCGATTTACCGCCCTCGGATAC
GTTGGCCCCTTCCGCCTATAAAAATGCCCATACGCTATTAAAAGTCGACAGGGGGCACCAGGCGCCGTTGGCAGGATTGG
GCGGCGTATCGGACTGGCCGTCGTTAAATTATTTATCGAATATTACGCCGCAGAAATCCGCCCTGAATCAGGGAGCATGG
GCTGCACTGGAAAACCGGGTGCGCGAACTTGCCAAACAGGCTGATGTATCTGTAGTGCACGTAGTGACCGGCCCCCTTTT
TGAGCGGCATATCGCCACATTGCCAGAAGATGCGACGGTAGAAATTCCCAGCGGGTACTGGAAGGTTTTATTCACCGGAA
TGGCGCCGTCAAAAAGTGAAGGAAATTACGCTGCATTTATTATGGATCAGAATACGCCCCGTTCGGCGAATTTTTGCGAC
TATCAGGTTACCGTGGAGGCTATCGAACATAAAGCGAAGCCAGTGCTGACGCTGTGGTCTGCTTTGCCTGAAGCGGTAGC
CAGCGAGGTGAAAACGACAAAGGGGAGTCTGGCGCAGAAGTTAGGTTGTCGATGA

Upstream 100 bases:

>100_bases
TGTTGTCTTTAATGATGAGAATATCTAACGGCTGTCAGGGTAATATAACCAAATTATTGCTATCTGAATTATTAGGGCAG
TTATTATTAAGGAAGAAAAA

Downstream 100 bases:

>100_bases
GAAGCGCTATACGGCGCGTAGAAAGATAACGGAGAAACCCTGTCAAGGGTCTTGATTTGCTATAGAGTGATGCAATCTCC
CTTTTTTTAGTGTTACCATC

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: Endonuclease [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSVTKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHTLLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGMAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKAKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR

Sequences:

>Translated_284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSVTKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHTLLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGMAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKAKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
>Mature_284_residues
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTIYRHVYTLNNNSVTKFANWVA
YSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHTLLKVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAW
AALENRVRELAKQADVSVVHVVTGPLFERHIATLPEDATVEIPSGYWKVLFTGMAPSKSEGNYAAFIMDQNTPRSANFCD
YQVTVEAIEHKAKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR

Specific function: Catalyzes the hydrolysis of both DNA and RNA, double- or single-stranded, at the 3'position of the phosphodiester bond to produce 5'-phosphorylated mono-, di-, tri- and tetranucleotides. DNA is a slightly better substrate than RNA [H]

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: =3.1.30.2 [H]

Molecular weight: Translated: 30862; Mature: 30862

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
YRHVYTLNNNSVTKFANWVAYSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHTLL
EEEEEEECCCCHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEE
KVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAWAALENRVRELAKQADVSVVH
EECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
VVTGPLFERHIATLPEDATVEIPSGYWKVLFTGMAPSKSEGNYAAFIMDQNTPRSANFCD
EECCHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
YQVTVEAIEHKAKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTINLLKLLPVVLLSACTTSYPPQDTTSAPELPHRNVLVQQPDNCSVGCPQGGSQQTI
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEE
YRHVYTLNNNSVTKFANWVAYSVTKTSQASGRPRNWAQDPDLPPSDTLAPSAYKNAHTLL
EEEEEEECCCCHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEE
KVDRGHQAPLAGLGGVSDWPSLNYLSNITPQKSALNQGAWAALENRVRELAKQADVSVVH
EECCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEE
VVTGPLFERHIATLPEDATVEIPSGYWKVLFTGMAPSKSEGNYAAFIMDQNTPRSANFCD
EECCHHHHHHHHCCCCCCEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCC
YQVTVEAIEHKAKPVLTLWSALPEAVASEVKTTKGSLAQKLGCR
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3319779; 8373817; 2665765; 8078761; 7804150; 8758988; 7664065; 9257723 [H]