Click here to switch to the map view.

The map label for this gene is yeaJ [H]

Identifier: 16764634

GI number: 16764634

Start: 1358285

End: 1359778

Strand: Reverse

Name: yeaJ [H]

Synonym: STM1283

Alternate gene names: 16764634

Gene position: 1359778-1358285 (Counterclockwise)

Preceding gene: 16764635

Following gene: 16764633

Centisome position: 27.99

GC content: 44.85

Gene sequence:

>1494_bases
ATGAATTTGCATCATAAAGCGCTCAGGCACTTTATCTCGGCAAGCGTCATCGTTTTGACATCGTCCTTCCTGATTTACGA
ACTTATTGCCAGCGACAGGGCAATGAATGCCTATATGCGTTATATCATGGAGAGAGCCGATTCGTCGTTTTTGTACGATA
AGTACCAGAATCAGAGCATCGCCGCACATTTGATGCGAACTTTTGAAGCGCCGGGAGACCCCGTCACCGCAGAAAAACAC
CGCGCGTTTTGCGACGCCTTTGAAGCTATTAACGGTACGCACGGTGTCAACCTGACCCGGCATAATTATCCGGCGCTACA
TGGTACTCTGCAAACCGCCGCTACACAGTGTACCGATAATCTTGATGACGCCCTTTTACTGCCTGCATTTGATCAGGCGG
TAAGCATCAACCGTTCGCAGGACGACCATAGTCACGGGCTGGGCACACTGGAGCTTAAATTCCGTTATTACGTTGATTTA
AATAAACATTATGTCTATTTCTATGATTTAATCAACTCACGGCGCTTCGCCATGCATCGTTGGACTTTTTTACAAAAAGG
CACAATGGGTATTAACAGAAAAGATATAGATAAACTTTTTACCGGCCGTACGGTTATTTCAAGTATCTACATGGATGATA
TTACTCAGGAAAACGTCATGAGTTTTTTAACGCCAGTCTATCTGGCGGGATCGTTAAAAGGCATCGTGATGGTGGATGTT
AACCAGGATAATTTAAAAAATATTTTTTATACCCAGGACCGTCCGCTGGTTTGGCGTTATCTTAACGTAACACTAAAGGA
TATGGACTCCGGAAAAGAAATTATTATTAATCAAAGCAAAAATAATCTGTTTCAATATGTGAATTATAGCCATGATATCC
CTGGTGGGCTGCGCGTTTCGTTGTCCCTTGATTTAACCTATTTCCTTGTCTCGTCCTGGAAAGCGCTGGCCTTTTACTTA
CTGGCAACGGCGCTCCTGCTTAATATGGTACGGATGCACTTTCGGCTTTATCGCAACGTCACACGCGAAAATATTAGCGA
TGCCATGACCGGGCTTTACAACCGTAAAATATTAACACCGGTGCTGGAACAGCGACTGCAACGCCTGGTCAATACCGGGA
CGCCGGTGACATTTGTCGCTATTGATTGCGATAGGTTAAAACTGATCAACGATACCCAGGGGCACCAGGAAGGCGACCGA
ATTATAACCCTGTTGGCGAAAGCGATTAAAACATCGATTCGTAAAAGCGATTACGCCATTCGCCTCGGCGGCGATGAGTT
CTGTATTATTCTTGTTGATTACGCGGCGGATTTGGCTATCCATCTGCCGGAGCGTATTATTCGTAACCTGCAAATTATCG
CACCGGATAAGACAGTCCATTTTTCTGCCGGGATTTATAATATGCAGCCCAATGATACGATTAATGATGCCTACCAGGCT
TCCGATGCGCAGCTCTATCTGAACAAACAACAAAAACAACATCGTTCATCATAG

Upstream 100 bases:

>100_bases
TTCCATAACATCAACACGTTTTATTTTTAAACAGTCTATTAGAGGAATTCTCATCGCTATGGTAAACTAACGCATCCGAC
TTTCAGGGCTGTAGTTCATC

Downstream 100 bases:

>100_bases
TGCTTCGCAGTAAATGTTCATATTGCACCAGGAGTGAGAAATGGCCGAAATGACTGAAGTCGCGAAGGGTGTCGCTACAC
ACCAACGTTTAGTGGCTTTA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIMERADSSFLYDKYQNQSIAAHLMRTFEAPGDPVTAEKH
RAFCDAFEAINGTHGVNLTRHNYPALHGTLQTAATQCTDNLDDALLLPAFDQAVSINRSQDDHSHGLGTLELKFRYYVDL
NKHYVYFYDLINSRRFAMHRWTFLQKGTMGINRKDIDKLFTGRTVISSIYMDDITQENVMSFLTPVYLAGSLKGIVMVDV
NQDNLKNIFYTQDRPLVWRYLNVTLKDMDSGKEIIINQSKNNLFQYVNYSHDIPGGLRVSLSLDLTYFLVSSWKALAFYL
LATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTPVLEQRLQRLVNTGTPVTFVAIDCDRLKLINDTQGHQEGDR
IITLLAKAIKTSIRKSDYAIRLGGDEFCIILVDYAADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQA
SDAQLYLNKQQKQHRSS

Sequences:

>Translated_497_residues
MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIMERADSSFLYDKYQNQSIAAHLMRTFEAPGDPVTAEKH
RAFCDAFEAINGTHGVNLTRHNYPALHGTLQTAATQCTDNLDDALLLPAFDQAVSINRSQDDHSHGLGTLELKFRYYVDL
NKHYVYFYDLINSRRFAMHRWTFLQKGTMGINRKDIDKLFTGRTVISSIYMDDITQENVMSFLTPVYLAGSLKGIVMVDV
NQDNLKNIFYTQDRPLVWRYLNVTLKDMDSGKEIIINQSKNNLFQYVNYSHDIPGGLRVSLSLDLTYFLVSSWKALAFYL
LATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTPVLEQRLQRLVNTGTPVTFVAIDCDRLKLINDTQGHQEGDR
IITLLAKAIKTSIRKSDYAIRLGGDEFCIILVDYAADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQA
SDAQLYLNKQQKQHRSS
>Mature_497_residues
MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIMERADSSFLYDKYQNQSIAAHLMRTFEAPGDPVTAEKH
RAFCDAFEAINGTHGVNLTRHNYPALHGTLQTAATQCTDNLDDALLLPAFDQAVSINRSQDDHSHGLGTLELKFRYYVDL
NKHYVYFYDLINSRRFAMHRWTFLQKGTMGINRKDIDKLFTGRTVISSIYMDDITQENVMSFLTPVYLAGSLKGIVMVDV
NQDNLKNIFYTQDRPLVWRYLNVTLKDMDSGKEIIINQSKNNLFQYVNYSHDIPGGLRVSLSLDLTYFLVSSWKALAFYL
LATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTPVLEQRLQRLVNTGTPVTFVAIDCDRLKLINDTQGHQEGDR
IITLLAKAIKTSIRKSDYAIRLGGDEFCIILVDYAADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQA
SDAQLYLNKQQKQHRSS

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87081974, Length=496, Percent_Identity=68.1451612903226, Blast_Score=723, Evalue=0.0,
Organism=Escherichia coli, GI145693134, Length=169, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082007, Length=219, Percent_Identity=30.1369863013699, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=30.0613496932515, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786584, Length=203, Percent_Identity=29.064039408867, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787262, Length=157, Percent_Identity=31.2101910828025, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788381, Length=127, Percent_Identity=33.8582677165354, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 56981; Mature: 56981

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIMERADSSFLYDKYQNQSI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCHH
AAHLMRTFEAPGDPVTAEKHRAFCDAFEAINGTHGVNLTRHNYPALHGTLQTAATQCTDN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
LDDALLLPAFDQAVSINRSQDDHSHGLGTLELKFRYYVDLNKHYVYFYDLINSRRFAMHR
CCCEEECCCCHHHHCCCCCCCCHHCCCEEEEEEEEEEEEECCCEEEEEEECCCCHHHHHH
WTFLQKGTMGINRKDIDKLFTGRTVISSIYMDDITQENVMSFLTPVYLAGSLKGIVMVDV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEC
NQDNLKNIFYTQDRPLVWRYLNVTLKDMDSGKEIIINQSKNNLFQYVNYSHDIPGGLRVS
CCCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCCHHHHCCCCCCCCCCEEEE
LSLDLTYFLVSSWKALAFYLLATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTP
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VLEQRLQRLVNTGTPVTFVAIDCDRLKLINDTQGHQEGDRIITLLAKAIKTSIRKSDYAI
HHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
RLGGDEFCIILVDYAADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQA
EECCCCEEEEEEECHHHHHHHCHHHHHCCCEEECCCCEEEEECCEEECCCCCCCCHHHCC
SDAQLYLNKQQKQHRSS
CCHHEEEEHHHHHCCCC
>Mature Secondary Structure
MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIMERADSSFLYDKYQNQSI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHCCCHH
AAHLMRTFEAPGDPVTAEKHRAFCDAFEAINGTHGVNLTRHNYPALHGTLQTAATQCTDN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCC
LDDALLLPAFDQAVSINRSQDDHSHGLGTLELKFRYYVDLNKHYVYFYDLINSRRFAMHR
CCCEEECCCCHHHHCCCCCCCCHHCCCEEEEEEEEEEEEECCCEEEEEEECCCCHHHHHH
WTFLQKGTMGINRKDIDKLFTGRTVISSIYMDDITQENVMSFLTPVYLAGSLKGIVMVDV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEC
NQDNLKNIFYTQDRPLVWRYLNVTLKDMDSGKEIIINQSKNNLFQYVNYSHDIPGGLRVS
CCCCCCCEEEECCCCEEEEEEEEEEECCCCCCEEEEECCCCCHHHHCCCCCCCCCCEEEE
LSLDLTYFLVSSWKALAFYLLATALLLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTP
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VLEQRLQRLVNTGTPVTFVAIDCDRLKLINDTQGHQEGDRIITLLAKAIKTSIRKSDYAI
HHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
RLGGDEFCIILVDYAADLAIHLPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQA
EECCCCEEEEEEECHHHHHHHCHHHHHCCCEEECCCCEEEEECCEEECCCCCCCCHHHCC
SDAQLYLNKQQKQHRSS
CCHHEEEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]