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The map label for this gene is dppB [C]

Identifier: 16764608

GI number: 16764608

Start: 1340757

End: 1341731

Strand: Direct

Name: dppB [C]

Synonym: STM1256

Alternate gene names: 16764608

Gene position: 1340757-1341731 (Clockwise)

Preceding gene: 16764607

Following gene: 16764609

Centisome position: 27.6

GC content: 52.92

Gene sequence:

>975_bases
ATGAAATTGTTCTTCAGTCATTTTTTGCGGCTGATTATTCTGTTGGTGCTGGTGGCTGCCGGCACCTTCATTTTGCTTAG
CTTTTCGCCCGTTGATCCTATCCGTGCTTATATTGGCAACGATCTGCTCCATGTTCCGCCAGAACAATATGCGCGGATTG
CGGCGCGCTGGGGGCTTGACCAGCCGCTGTGGGAGCGTTTCGGTCACTGGTTTTGGCGTCTGCTCCAGGGCGACATGGGG
TATTCCATGCTGTTCAACATGCCTGTCGCCAGTGTGATCCGGGAACGTTTTGCGACGTCATTCGCGCTGCTGGCAGGCGC
CTGGCTATTGTCTGGTGTGCTGGGCGTGACATTGGGTTTTCTGGCCGGACGTTTTCTCCACCGTTGGCCGGATAAGATGA
TTTGCCGTATCAGCTACTTATTGTCATCGTTGCCCACTTTCTGGATAGCCATGTTGTTGCTGGCGCTGTTTGCCGTCCGC
TGGCCGGTATTACCTGTTTGTTGCGCCTGGGACCCCGGAAATAATGCAGGAACAGCTCTTTTATCGGAACGTTTACGCCA
TCTTGTGTTGCCGGTATGTGCGTTAAGTCTGTTGGGCATGGGGCAAATTGCGCTGCATACGCGAGAAAAAATAGCCAGTG
TAATGAAGAGCGAATTTATTCGTTTTGCGCGCGCTCAGGGGGATAAAGGATGGTCGCTGTTACGTCACCAGGTGTTACGT
CATGCGATTACCCCAGCACTCTGTTTACAGTTTGCTTCTCTGGGCGAACTGATGGGGGGAGCGTTACTGGCAGAAAAAGT
CTTTGCGTATCCGGGGCTGGGACAGGCCACTATCGATGCCGGCCTGCGTGGCGATGTCCCGCTACTCATGGGGATCGTTT
TATTCTGTACACTATTAGTGTTTGCCGGAAATACGATTTCAGCCTGGCTTGTGGTGGTGCTTAATCGATCGCTGGAGCGT
CCCGATGCTCTATAA

Upstream 100 bases:

>100_bases
TGGCCAACCCCTGTATTGATCTGGGAAAAGGCGCGCCAGAAATCCACGGTAGCTGGTCGGTGTTAAACAATCTTGATGAC
TGGACCTGGACCTGTCGGTG

Downstream 100 bases:

>100_bases
TCCTGCCCCGACGTTGTTTCGTCTGCTCCTCTCCGTTACCTGTCTGCTGTTTATTGCCGGATACGGTTATGCCACGTTGA
GCCAGCCGCCAGAGGTTAAT

Product: ABC transporter protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDMG
YSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVR
WPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVLR
HAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLER
PDAL

Sequences:

>Translated_324_residues
MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDMG
YSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVR
WPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVLR
HAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLER
PDAL
>Mature_324_residues
MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDMG
YSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVR
WPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVLR
HAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLER
PDAL

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=312, Percent_Identity=29.1666666666667, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787053, Length=324, Percent_Identity=29.0123456790123, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=27.0186335403727, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1787761, Length=308, Percent_Identity=31.4935064935065, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787497, Length=326, Percent_Identity=27.6073619631902, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=28.5714285714286, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788504, Length=276, Percent_Identity=26.4492753623188, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36008; Mature: 36008

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLD
CCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEECCHHHHHHHHHHCCCC
QPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGF
HHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVRWPVLPVCCAWDPGNNAGTAL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHH
LSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVLR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FAGNTISAWLVVVLNRSLERPDAL
HHCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLD
CCHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEECCHHHHHHHHHHCCCC
QPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFALLAGAWLLSGVLGVTLGF
HHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVRWPVLPVCCAWDPGNNAGTAL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCHHHHH
LSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSEFIRFARAQGDKGWSLLRHQVLR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HAITPALCLQFASLGELMGGALLAEKVFAYPGLGQATIDAGLRGDVPLLMGIVLFCTLLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FAGNTISAWLVVVLNRSLERPDAL
HHCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]